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Nasopharyngeal Flora in the First Three Years of Life in Normal and Otitis-Prone Children
Abstract
Nasopharyngeal carriage of the three major middle ear pathogens ( Streptococcus pneumoniae, nontypeable Hemophilus influenzae, and Moraxella catarrhalis) was evaluated prospectively in a group of 110 children followed up for the first 3 years of life. The findings suggested that nasopharyngeal carriage of middle ear pathogens increases significantly during respiratory illness among the general population of young children; however, otitis-prone children demonstrated a tendency to carry nontypeable H influenzae at an unusually high rate even during health. This propensity to carry nontypeable H influenzae might explain why nontypeable H influenzae is a major cause of recurrent or chronic otitis media.
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Citations
Cited by
Relationship between Nasopharyngeal Colonization and the Development of Otitis Media in Children
Faden, H., Duffy, L., Wasielewski, R., Wolf, J., Krystofik, D., Tung, Y., & Pediatrics, T. (1997) · The Journal of Infectious Diseases · doi:10.1086/516477 · Cited by 502
Self-citationKILPI, T., HERVA, E., KAIJALAINEN, T., SYRJÄNEN, R., & TAKALA, A. K. (2001) · The Pediatric Infectious Disease Journal · doi:10.1097/00006454-200107000-00004 · Cited by 299
Respiratory viruses predisposing to bacterial infections: role of neuraminidase.
PELTOLA, V. T., & MCCULLERS, J. A. (2004) · Pediatric Infectious Disease Journal · doi:10.1097/01.inf.0000108197.81270.35 · Cited by 290
Faden, H., Harabuchi, Y., Hong, J. J., & Pediatrics, T. (1994) · Journal of Infectious Diseases · doi:10.1093/infdis/169.6.1312 · Cited by 175
Self-citationDeMuri, G. P., Gern, J. E., Eickhoff, J. C., Lynch, S. V., & Wald, E. R. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/cix941 · Cited by 136
Metadata
- Authors
- Faden, H., Brodsky, L., Waz, M. J., Stanievich, J., Bernstein, J. M., & Ogra, P. L.
- Venue
- Annals of Otology, Rhinology & Laryngology
- Publisher
- SAGE Publications
- Published
- 1991-08
- Volume
- 100
- Issue
- 8
- Pages
- 612-615
- ISSN
- 0003-4894 (ISSN-L)
- 1943-572X
- OpenAlex
- W2007851903
- Cited by
- 200
- References
- 0
- FWCI
- 4.63
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Nasopharyngeal Flora in the First Three Years of Life in Normal and Otitis-Prone Children. https://app.cochat.ai/papers/10.1177/000348949110000802
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- Faden, H., Brodsky, L., Waz, M. J., Stanievich, J., Bernstein, J. M., & Ogra, P. L. (1991). Nasopharyngeal Flora in the First Three Years of Life in Normal and Otitis-Prone Children. Annals of Otology, Rhinology & Laryngology. https://doi.org/10.1177/000348949110000802
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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