A Quantitative Assessment of the Efficacy of Surgical and N95 Masks to Filter Influenza Virus in Patients with Acute Influenza Infection
Abstract
We assessed the in vivo efficacy of surgical and N95 (respirator) masks to filter reverse transcription-polymerase chain reaction (RT-PCR)-detectable virus when worn correctly by patients with laboratory-confirmed acute influenza. Of 26 patients with a clinical diagnosis of influenza, 19 had the diagnosis confirmed by RT-PCR, and 9 went on to complete the study. Surgical and N95 masks were equally effective in preventing the spread of PCR-detectable influenza.
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The efficacy of surgical masks and N95 filtering facepiece respirators was found to be similar in preventing the spread of influenza virus from patients.
“The efficacy of SMs and N95 FFRs was found to be similar in preventing the spread of influenza virus from patients.”
SMs were found to be as effective as N95 FFRs against aerosol particles similar to the size of infectious aerosols.
“However, SMs were found to be as effective as N95 FFRs against aerosol particles similar to the size of infectious aerosols. (17,19,20)”
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- Authors
- Johnson, D. F., Druce, J. D., Birch, C., & Grayson, M. L.
- Affiliations
- Austin Hospital (AU)
- Victorian Infectious Diseases Reference Laboratory (AU)
- The University of Melbourne (AU)
- Corresponding author
- Grayson, M. L.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-07-15
- Volume
- 49
- Issue
- 2
- Pages
- 275-277
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2160453697
- Cited by
- 211
- References
- 10
- Citations by year
- 2025: 6 · 2024: 5 · 2023: 20 · 2022: 21 · 2021: 37 · 2020: 51 · 2019: 1 · 2018: 4 · 2017: 3 · 2016: 6 · 2015: 4 · 2014: 6 · 2013: 12 · 2012: 4
- FWCI
- 9.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Infection Control and Ventilation
- Health Sciences › Medicine › Epidemiology › Influenza Virus Research Studies
- Health Sciences › Medicine › Infectious Diseases › Infection Control in Healthcare
- Keywords
- influenza virus, surgical masks, N95 respirators, respiratory protection, airborne transmission, viral load, respiratory droplets, infection control
- MeSH terms
- Adult, Aged, Aged, 80 and over, Humans, Influenza, Human, Middle Aged, Orthomyxoviridae, Respiratory Protective Devices, RNA, Viral, Reverse Transcriptase Polymerase Chain Reaction, Young Adult
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