Disposable blood potassium sensors based on screen-printed thick film electrodes
Abstract
A sensor based on the screen-printing technique for the rapid blood potassium test was developed. The sensor consists of a thick film potassium ion-selective electrode and a reference electrode. Poly(3,4-ethylenedioxythiophene) (PEDOT) doped with poly(styrenesulfonate) (PSS) was screen-printed on carbon electrodes as an internal solid contact layer for both ion-selective and reference electrodes. PVC membranes with and without selective ionphore valinomycin were coated on the PEDOT/PSS layer to form potassium ion-selective and reference electrodes, respectively. The potentiometric response characters were evaluated. The response time of the sensor was 15 s when less than 15 µL of sample was applied. The sensitivity of the potassium sensor was around 60 mV per decade, while the potentiometric log selectivity coefficients were −3.43 and −3.48 for Na + and Ca 2+ , respectively.
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The K+ sensor demonstrated a smaller and faster response compared to current standard of care (e.g., clinical laboratory electrolyte analyzer) and required a smaller blood sample volume.
“The sensor demonstrated a smaller and faster response compared to current standard of care (e.g., clinical laboratory electrolyte analyzer) and required a smaller blood sample volume.”
From Wearable sensors for monitoring the physiological and biochemical profile of the athlete (2019) · cites this paper as [43]
Xu et al. devised a low-cost method to mass produce disposable portable sensors for point of care testing of K+ from blood serum.
“Xu et al.43 devised a low-cost method to mass produce disposable portable sensors for point of care testing of K+ from blood serum.”
From Wearable sensors for monitoring the physiological and biochemical profile of the athlete (2019) · cites this paper as [43]
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Wearable sensors for monitoring the physiological and biochemical profile of the athlete
Seshadri, D. R., Li, R. T., Voos, J. E., Rowbottom, J. R., Alfes, C. M., Zorman, C. A., & Drummond, C. K. (2019) · npj Digital Medicine · doi:10.1038/s41746-019-0150-9 · Cited by 537 · see citing works
- Authors
- Xu, H., Yang, X., Wang, Y., Zheng, J., Luo, Z., & Li, G.
- Affiliations
- State Key Laboratory of Industrial Control Technology (CN)
- Zhejiang University (CN)
- Zhejiang Sci-Tech University (CN)
- Royal Holloway University of London (GB)
- Venue
- Measurement Science and Technology
- Publisher
- IOP Publishing
- Published
- 2010-04-13
- Volume
- 21
- Issue
- 5
- Pages
- 055802
- ISSN
- 0957-0233 (ISSN-L)
- 1361-6501
- OpenAlex
- W2059222337
- Cited by
- 14
- References
- 24
- Citations by year
- 2021: 1 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 1 · 2013: 1 · 2012: 2
- FWCI
- 0.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Measurement Science and Technology (publishedVersion)
- Topics
- Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Physical Sciences › Materials Science › Polymers and Plastics › Conducting polymers and applications
- Keywords
- disposable sensors, screen-printed electrodes, thick-film electrodes, ion-selective electrodes, reference electrode, PEDOT:PSS, valinomycin, PVC membrane, potentiometric sensors, carbon electrodes
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