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Luminescent nanomaterials for biological labelling
Open accessAbstract
The use of labelling or staining agents has greatly assisted the study of complex biological interactions in the field of biology. In particular, fluorescent labelling of biomolecules has been demonstrated as an indispensable tool in many biological studies. Types of fluorescent labelling agents that are commonly used include conventional classes of organic fluorophores such as fluorescein and cyanine dyes, as well as newer types of inorganic nanoparticles such as QDs, and novel fluorescent latex/silica nanobeads. The newer classes of fluorescent labels are gaining increasing popularity in place of their predecessors due to their better optical properties such as possessing an enhanced photostability and a larger Stokes shift over conventional organic fluorophores, for example. This paper gives an overview of the recent advances on these luminescent nanomaterials with emphases on their optical characteristics that are crucial in fluorescence microscopy, both advantages and limitations in their usage as well as challenges they face, and puts forward the future direction of fluorescent labels in the area of biolabelling.
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Cites
Perspectives on the Physical Chemistry of Semiconductor Nanocrystals
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Cited by
Ultra-small fluorescent metal nanoclusters: Synthesis and biological applications
Shang, L., Dong, S., & Nienhaus, G. U. (2011) · Nano Today · doi:10.1016/j.nantod.2011.06.004 · Cited by 1,502
Biological applications of quantum dots
Jamieson, T., Bakhshi, R., Petrova, D., Pocock, R., Imani, M., & Seifalian, A. M. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.014 · Cited by 1,107
Burns, A., Ow, H., & Wiesner, U. (2006) · Chem. Soc. Rev. · doi:10.1039/b600562b · Cited by 849
Li, Z., & Zhang, Y. (2006) · Angewandte Chemie International Edition · doi:10.1002/anie.200602975 · Cited by 484
Self-citationWater-soluble quantum dots for biomedical applications
Yu, W. W., Chang, E., Drezek, R., & Colvin, V. L. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.07.160 · Cited by 435
Metadata
- Authors
- Wang, F., Tan, W. B., Zhang, Y., Fan, X., & Wang, M.
- Venue
- Nanotechnology
- Publisher
- IOP Publishing
- Published
- 2005-11-25
- Volume
- 17
- Issue
- 1
- Pages
- R1-R13
- ISSN
- 0957-4484 (ISSN-L)
- 1361-6528
- OpenAlex
- W2170472008
- Cited by
- 547
- References
- 3
- FWCI
- 13.10
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Wang, F., Tan, W. B., Zhang, Y., Fan, X., & Wang, M. (2006). Luminescent nanomaterials for biological labelling. Nanotechnology. https://doi.org/10.1088/0957-4484/17/1/r01
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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