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A tapered hollow metallic microneedle array using backside exposure of SU-8
Open accessAbstract
This paper presents a novel fabrication process for a tapered hollow metallic microneedle array using backside exposure of SU-8, and analytic solutions of critical buckling of a tapered hollow microneedle. An SU-8 mesa was formed on a Pyrex glass substrate and another SU-8 layer, which was spun on top of the SU-8 mesa, was exposed through the backside of the glass substrate. An array of SU-8 tapered pillar structures, with angles in the range of 3.1°–5°, was formed on top of the SU-8 mesa. Conformal electrodeposition of metal was carried out followed by a mechanical polishing using a planarizing polymeric layer. All organic layers were then removed to create a metallic hollow microneedle array with a fluidic reservoir on the backside. Both 200 µm and 400 µm tall, 10 by 10 arrays of metallic microneedles with inner diameters of the tip in the range of 33.6–101 µm and wall thickness of 10–20 µm were fabricated. Analytic solutions of the critical buckling of arbitrary-angled truncated cone-shaped columns are also presented. It was found that a single 400 µm tall hollow cylindrical microneedle made of electroplated nickel with a wall thickness of 20 µm, a tapered angle of 3.08° and a tip inner diameter of 33.6 µm has a critical buckling force of 1.8 N. This analytic solution can be used for square or rectangular cross-sectioned column structures with proper modifications.
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Citations
Cited by
Microneedles for drug and vaccine delivery
Kim, Y.-C., Park, J.-H., & Prausnitz, M. R. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.04.005 · Cited by 1,760
Xiang, Z., Liu, J., & Lee, C. (2016) · Microsystems & Nanoengineering · doi:10.1038/micronano.2016.12 · Cited by 100
Varying-Length Polymer Microneedle Arrays Fabricated by Droplet Backside Exposure
Kwon, K. Y., Weber, A., & Li, W. (2014) · Journal of Microelectromechanical Systems · doi:10.1109/jmems.2014.2352412 · Cited by 23
Metadata
- Authors
- Kim, K., Park, D. S., Lu, H. M., Che, W., Kim, K., Lee, J.-B., & Ahn, C. H.
- Venue
- Journal of Micromechanics and Microengineering
- Publisher
- IOP Publishing
- Published
- 2004-02-06
- Volume
- 14
- Issue
- 4
- Pages
- 597-603
- ISSN
- 0960-1317 (ISSN-L)
- 1361-6439
- OpenAlex
- W2134785604
- Cited by
- 210
- References
- 0
- FWCI
- 12.43
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Kim, K., Park, D. S., Lu, H. M., Che, W., Kim, K., Lee, J.-B., & Ahn, C. H. (2004). A tapered hollow metallic microneedle array using backside exposure of SU-8. Journal of Micromechanics and Microengineering. https://doi.org/10.1088/0960-1317/14/4/021
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