Cited by 408Optical Imaging and Spectroscopy TechniquesSpectroscopy Techniques in Biomedical and Chemical ResearchOptical Polarization and Ellipsometry

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Quantitative assessment of skin layers absorption and skin reflectance spectra simulation in the visible and near-infrared spectral regions

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Meglinski, Igor V, Matcher, Stephen J·2002·Physiological Measurement

DOI 10.1088/0967-3334/23/4/312

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Abstract

We have simulated diffuse reflectance spectra of skin by assuming a wavelength-independent scattering coefficient for the different skin tissues and using the known wavelength dependence of the absorption coefficient of oxy- and deoxyhaemoglobin and water. A stochastic Monte Carlo method is used to convert the wavelength-dependent absorption coefficient and wavelength-independent scattering coefficient into reflected intensity. The absorption properties of skin tissues in the visible and near-infrared spectral regions are estimated by taking into account the spatial distribution of blood vessels, water and melanin content within distinct anatomical layers. The geometrical peculiarities of skin histological structure, degree of blood oxygenation and the haematocrit index are also taken into account. We demonstrate that when the model is supplied with reasonable physical and structural parameters of skin, the results of the simulation agree reasonably well with the results of in vivo measurements of skin spectra.

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Authors: Meglinski, I. V., & Matcher, S. J.
Affiliations: Cranfield University (GB)
University of Exeter (GB)
ORCID: Meglinski, Igor V
Matcher, Stephen J
Venue: Physiological Measurement
Publisher: IOP Publishing
Published: 2002-10-17
Volume: 23
Issue: 4
Pages: 741-753
ISSN: 0967-3334 (ISSN-L)
DOI: 10.1088/0967-3334/23/4/312
OpenAlex: W2053040583
Cited by: 408
References: 36
Citations by year: 2026: 9 · 2025: 16 · 2024: 24 · 2023: 25 · 2022: 28 · 2021: 26 · 2020: 25 · 2019: 25 · 2018: 14 · 2017: 14 · 2016: 19 · 2015: 22 · 2014: 26 · 2013: 19 · 2012: 15
FWCI: 4.85
Type: journal article
Language: en
Open access: green
dspace.lib.cranfield.ac.uk
Locations: Physiological Measurement (publishedVersion)
PubMed (publishedVersion)
CERES (Cranfield University) (submittedVersion)
Funders: Engineering and Physical Sciences Research Council
Topics: Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Optical Imaging and Spectroscopy Techniques
Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Spectroscopy Techniques in Biomedical and Chemical Research
Physical Sciences › Physics and Astronomy › Atomic and Molecular Physics, and Optics › Optical Polarization and Ellipsometry
Keywords: diffuse reflectance, Monte Carlo light transport, hemoglobin absorption, melanin, water uptake (human physiology), skin histology, blood oxygenation, hematocrit, skin layers, visible and near-infrared spectroscopy, spectral simulation
MeSH terms: Absorption, Algorithms, Humans, Light, Models, Biological, Monte Carlo Method, Skin, Skin Physiological Phenomena, Spectroscopy, Near-Infrared, Optics and Photonics

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Quantitative assessment of skin layers absorption and skin reflectance spectra simulation in the visible and near-infrared spectral regions

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