The DOI matches its Crossref record; 112 of the 113 references it cites were found in a registry or an index.
Development of a cortical visual neuroprosthesis for the blind: the relevance of neuroplasticity
Abstract
Clinical applications such as artificial vision require extraordinary, diverse, lengthy and intimate collaborations among basic scientists, engineers and clinicians. In this review, we present the state of research on a visual neuroprosthesis designed to interface with the occipital visual cortex as a means through which a limited, but useful, visual sense could be restored in profoundly blind individuals. We review the most important physiological principles regarding this neuroprosthetic approach and emphasize the role of neural plasticity in order to achieve desired behavioral outcomes. While full restoration of fine detailed vision with current technology is unlikely in the immediate near future, the discrimination of shapes and the localization of objects should be possible allowing blind subjects to navigate in a unfamiliar environment and perhaps even to read enlarged text. Continued research and development in neuroprosthesis technology will likely result in a substantial improvement in the quality of life of blind and visually impaired individuals.
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“In response to the loss of vision, brain areas normally devoted to the processing of visual information are recruited to process tactile and auditory information and even cognitive functions such as verbal memory and speech processing (Fernandez et al., 2005; Gilbert et al., 2009; Legge and Chung, 2016; Beyeler et al., 2017; Singh et al., 2018; Castaldi et al., 2020).”
From Toward Long-Term Communication With the Brain in the Blind by Intracortical Stimulation: Challenges and Future Prospects (2020) · cites this paper as Fernandez et al., 2005
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Cites
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Items 101–105 of 105
Ortega, A. M. L. (2022) · Digital Repository (Polytechnic University of Cartagena) · doi:10.31428/10317/11200
Retinal/Visual Interfaces (Models, Theory, Techniques): Overview
Lovell, N. H. (2022) · Encyclopedia of Computational Neuroscience · doi:10.1007/978-1-0716-1006-0_789
Retinal/Visual Interfaces (Models, Theory, Techniques): Overview
Lovell, N. H. (2014) · Encyclopedia of Computational Neuroscience · doi:10.1007/978-1-4614-7320-6_789-1
Charge Pumps for Implantable Microstimulators in Low and High-Voltage Technologies
Kar, G. C. (2013) · PolyPublie (École Polytechnique de Montréal)
Metadata
- Authors
- Fernández, E., Pelayo, F., Romero, S., Bongard, M., Marin, C., Alfaro, A., & Merabet, L.
- Affiliations
- Universitat de Miguel Hernández d'Elx (ES)
- Universidad de Granada (ES)
- Venue
- Journal of Neural Engineering
- Publisher
- IOP Publishing
- Published
- 2005-11-29
- Volume
- 2
- Issue
- 4
- Pages
- R1-R12
- ISSN
- 1741-2552 (ISSN-L)
- 1741-2560
- OpenAlex
- W2063850540
- Cited by
- 105
- References
- 113
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 7 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 3 · 2016: 4 · 2015: 7 · 2014: 6 · 2013: 4 · 2012: 8
- FWCI
- 0.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neural Engineering (publishedVersion)
- PubMed (publishedVersion)
- Funders
- University of Utah
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Life Sciences › Neuroscience › Cognitive Neuroscience › EEG and Brain-Computer Interfaces
- Keywords
- cortical visual prosthesis, neuroplasticity, blindness, vision restoration, shape discrimination, object localization, navigation, visually impaired people
- MeSH terms
- Artificial Intelligence, Blindness, Electric Stimulation Therapy, Humans, Neuronal Plasticity, Optic Nerve, Prosthesis Design, Retinal Ganglion Cells, Visual Cortex, Prostheses and Implants
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