The DOI matches its Crossref record; 52 of the 53 references it cites were found in a registry or an index.
Bioglass incorporated methacrylated collagen bioactive ink for 3D printing of bone tissue
Open accessAbstract
Bioactive three-dimensional (3D) printed scaffolds are promising candidates for bone tissue engineering (BTE) applications. Here, we introduce a bioactive ink composed of Bioglass 45S5 (BG) and methacrylated collagen (CMA) for 3D printing of biomimetic constructs that resemble the organic and inorganic composition of native bone tissue. A uniform dispersion of BG particles within the collagen network improved stability and reduced swelling of collagen hydrogels. Rheological testing showed significant improvement in the yield stress and percent recovery of 3D printed constructs upon BG incorporation. Further, addition of BG improved the bone bioactivity of 3D printed constructs in stimulated body fluid. BG incorporated CMA (BG-CMA) constructs maintained high cell viability and enhanced alkaline phosphatase activity of human mesenchymal stem cells. In addition, cell-mediated calcium deposition was significantly higher on BG-CMA constructs, compared to CMA alone. In conclusion, 3D printed BG-CMA constructs have significant potential for use in BTE applications.
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“Nevertheless, despite these improvements, ColMA-based hydrogels still exhibit insufficient mechanical robustness, limiting their ability to maintain dimensional accuracy during extrusion-based bioprinting [15,16].”
From Montmorillonite-reinforced methacrylated collagen/methacrylated silk fibroin hydrogel-based inks: rheological and physicochemical characterization for bone scaffold applications (2026) · cites this paper as [15]
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Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
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Embedded bioprinting for designer 3D tissue constructs with complex structural organization
Zeng, X., Meng, Z., He, J., Mao, M., Li, X., Chen, P., Fan, J., & Li, D. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.11.048 · Cited by 90
Nanocomposite Bioprinting for Tissue Engineering Applications
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Metadata
- Authors
- Kajave, N. S., Schmitt, T., Nguyen, T.-U., Gaharwar, A. K., & Kishore, V.
- Affiliations
- Florida Institute of Technology (US)
- Texas A&M University (US)
- Corresponding author
- Kishore, Vipuil
- Venue
- Biomedical Materials
- Publisher
- IOP Publishing
- Published
- 2021-02-26
- Volume
- 16
- Issue
- 3
- Pages
- 035003
- ISSN
- 1748-6041 (ISSN-L)
- 1748-605X
- PMC
- PMC8326306
- OpenAlex
- W3096856907
- Cited by
- 46
- References
- 53
- Citations by year
- 2026: 6 · 2025: 9 · 2024: 8 · 2023: 8 · 2022: 9 · 2021: 6
- FWCI
- 1.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biomedical Materials (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Center for Scientific Review (1R15AR071102)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Engineering › Building and Construction › Innovations in Concrete and Construction Materials
- Keywords
- 45S5 bioactive glass, 3D bioprinting, bone tissue engineering, collagen gel, rheological properties, mesenchymal stem cells, alkaline phosphatase activity, calcium deposition
- MeSH terms
- Bone and Bones, Ceramics, Collagen, Humans, Ink, Tissue Engineering, Tissue Scaffolds, Mesenchymal Stem Cells, Printing, Three-Dimensional
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