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Cited by 40Adrenal and Paraganglionic TumorsMinimally Invasive Surgical TechniquesPituitary Gland Disorders and Treatments

Transperitoneal laparoscopic adrenalectomy: experience in 72 procedures

Porpiglia, F., Garrone, C., Giraudo, G., Destefanis, P., Fontana, D., Morino, M.·2001·Journal of Endourology
DOI 10.1089/089277901750161755
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Abstract

PURPOSE: To evaluate the safety and effectiveness of transperitoneal laparoscopic adrenalectomy for a variety of adrenal diseases. PATIENTS AND METHODS: Seventy-two patients underwent laparoscopic adrenalectomy from January 1995 until March 1999. The indications for the treatment were limited to either functioning or nonfunctioning adrenal masses without radiologic evidence of involvement of the surrounding tissues. The indication for bilateral adrenalectomy was Cushing's disease after the failure of other therapies or Cushing's syndrome secondary to ectopic ACTH secretion without the discovery of a primary neoplasm. RESULTS: Thirty-five of the adrenalectomies were performed on the left side and 33 on the right side, and 4 were performed bilaterally. The right-sided procedures required a mean operating time of 130 minutes (range 85-200 minutes), the left-sided procedures required a mean operating time of 140 minutes (range 95-200 minutes), and the bilateral procedures required a mean operating time of 240 minutes (range 210-290 minutes). A conversion from laparoscopy to laparotomy was necessary for 3 patients (4%). Intraoperative complications were reported in 6 patients (8%). Postoperative complications likewise occurred in six patients. CONCLUSIONS: These procedures proved to be safe and able to remove the majority of either functioning or nonfunctioning benign adrenal masses. Some controversy remains regarding the safety of laparoscopic adrenalectomy for large lesions and the safety of bilateral laparoscopic adrenalectomy because of bleeding risks, anesthetic risks, and long operative times. The effectiveness of laparoscopic adrenalectomy for nonfunctioning adrenal masses with histologic findings of carcinoma has not yet been proved.

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Crossref · 10.1089/089277901750161755

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21 of 21 references verified0 citation errors · 0 not checkable

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  • Other studies reported evidence that LA may be comparable to OA in patients with stage 1 and 2 ACC based on no significant difference in recurrence-free survival.

    “In contrast, other studies reported evidence that LA may be comparable to OA in patients with stage 1 and 2 ACC based on no significant difference in recurrence-free survival (259, 260).”

    From Adrenocortical carcinoma (2014) · cites this paper as [260]

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Authors
Porpiglia, F., Garrone, C., Giraudo, G., Destefanis, P., Fontana, D., & Morino, M.
Affiliations
  • Ospedale San Luigi Gonzaga (IT)
  • Azienda Ospedaliero Universitaria San Giovanni Battista (IT)
ORCID
Venue
Journal of Endourology
Publisher
SAGE Publications
Published
2001-04
Volume
15
Issue
3
Pages
275-279
ISSN
  • 0892-7790 (ISSN-L)
  • 1557-900X
DOI
10.1089/089277901750161755
OpenAlex
W1972517818
Cited by
40
References
21
Citations by year
2024: 1 · 2021: 1 · 2015: 2 · 2014: 1 · 2013: 2
FWCI
5.28
Type
journal article
Language
en
Open access
closed
Licence
www.liebertpub.com/nv/resources-tools/text-and-data-mining-policy/121/ (tdm)
Locations
  • Journal of Endourology (publishedVersion)
  • PubMed (publishedVersion)
  • Institutional Research Information System University of Turin (University of Turin) (submittedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
  • Health Sciences › Medicine › Surgery › Minimally Invasive Surgical Techniques
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
Keywords
laparoscopic adrenalectomy, transperitoneal approach, adrenal mass, Cushing's disease, ectopic ACTH syndrome, bilateral adrenalectomy, conversion to open surgery, intraoperative complications, postoperative complications, adrenocortical carcinoma, operative time
MeSH terms
Adolescent, Adrenalectomy, Adult, Aged, Aged, 80 and over, Child, Humans, Intraoperative Complications, Laparotomy, Middle Aged, Laparoscopy, Postoperative Complications, Retrospective Studies

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