The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Glutamatergic Changes with Treatment in Attention Deficit Hyperactivity Disorder: A Preliminary Case Series
Abstract
Magnetic resonance spectroscopy, a noninvasive neuroimaging method, is a technique with the potential to measure in vivo neurochemical changes to different medication treatments. Symptoms of attention deficit hyperactivity disorder (ADHD) improved in two children treated with methylphenidate and two children treated with atomoxetine, for whom pre- and posttreatment proton magnetic resonance spectroscopy examinations were obtained to assess the relation between the neurochemical profiles in the striatum and prefrontal cortex among symptom severity and response to treatment. In the striatum, a striking decrease in the glutamate/creatine ratio (mean change 56.1%) was observed between 14 and 18 weeks of therapy in all four children with ADHD. In the prefrontal cortex, however, changes in the glutamate/creatine ratio were noted only in subjects receiving atomoxetine, not in those receiving methylphenidate. These data suggest that in vivo magnetic resonance spectroscopy measurement has the potential to assess response to psychopharmacological treatment in children with ADHD.
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“Results of the few studies that have examined the effect of stimulants on left PFC glutamate levels are inconsistent and have shown that stimulants either decrease (Wiguna et al, 2012) or have no effect (Carrey et al, 2002; Husarova et al, 2014b) on glutamate concentrations.”
From Lisdexamfetamine Effects on Executive Activation and Neurochemistry in Menopausal Women with Executive Function Difficulties (2017) · cites this paper as Carrey et al, 2002
Citations
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Sani, G., Serra, G., Kotzalidis, G. D., Romano, S., Tamorri, S. M., Manfredi, G., Caloro, M., Telesforo, C. L., Caltagirone, S. S., Panaccione, I., et al. (2012) · CNS Drugs · doi:10.2165/11634390-000000000-00000 · Cited by 273
Atomoxetine for hyperactivity in autism spectrum disorders: placebo-controlled crossover pilot trial
ARNOLD, L. E., AMAN, M. G., COOK, A. M., WITWER, A. N., HALL, K. L., THOMPSON, S., & RAMADAN, Y. (2006) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000231976.28719.2a · Cited by 260
Non?stimulant medications in the treatment of ADHD
Banaschewski, T., Roessner, V., Dittmann, R. W., Janardhanan Santosh, P., & Rothenberger, A. (2004) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-004-1010-x · Cited by 183
Striatal Creatine and Glutamate/Glutamine in Attention-Deficit/Hyperactivity Disorder
Carrey, N. J., MacMaster, F. P., Gaudet, L., & Schmidt, M. H. (2007) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2006.0008 · Cited by 117
Self-citationNaaijen, J., Lythgoe, D. J., Amiri, H., Buitelaar, J. K., & Glennon, J. C. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.02.009 · Cited by 117
Agmatine rescues autistic behaviors in the valproic acid-induced animal model of autism
Kim, J.-W., Seung, H., Kim, K. C., Gonzales, E. L. T., Oh, H. A., Yang, S. M., Ko, M. J., Han, S.-H., Banerjee, S., & Shin, C. Y. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2016.09.014 · Cited by 102
Shanmugan, S., Loughead, J., Nanga, R. P. R., Elliott, M., Hariharan, H., Appleby, D., Kim, D., Ruparel, K., Reddy, R., Brown, T. E., et al. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.162 · Cited by 33
Metadata
- Authors
- Carrey, N., MacMaster, F. P., Sparkes, S. J., Khan, S. C., & Kusumakar, V.
- Venue
- Journal of Child and Adolescent Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2002-12
- Volume
- 12
- Issue
- 4
- Pages
- 331-336
- ISSN
- 1044-5463
- 1557-8992
- Cited by
- 49
- References
- 2
- Language
- en
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