Aging and Immune Function: Molecular Mechanisms to Interventions
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Items 101–200 of 339
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- Role of Hormones in the Regulation of RACK1 Expression as a Signaling Checkpoint in ImmunosenescenceMarco Racchi, Erica Buoso, Melania Ronfani, Melania Maria Serafini, Marilisa Galasso, Cristina Lanni, Emanuela Corsini · 2017 · International Journal of Molecular Sciences
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- Potential of Mesenchymal Stem Cells in the Rejuvenation of the Aging Immune SystemGenieve Ee Chia Yeo, Min Hwei Ng, Fazlina Nordin, Jia Xian Law · 2021 · International Journal of Molecular Sciences
- A Longitudinal Study of the Association Between Persistent Pathogens and Incident Depression Among Older U.S. LatinosAmanda M. Simanek, Cheng Zheng, Robert H. Yolken, Mary N. Haan, Allison E. Aiello · 2018 · The Journals of Gerontology Series A
- Immune Function and Muscle Adaptations to Resistance exercise in Older Adults: Study Protocol for a Randomized Controlled Trial of a Nutritional SupplementRichard A. Dennis, Usha Ponnappan, Ralph L. Kodell, Kimberly K. Garner, Christopher M. Parkes, Melinda M. Bopp, Kalpana P. Padala, Charlotte A. Peterson, Prasad R. Padala, Dennis H. Sullivan · 2015 · Trials
- Dysregulation of antimicrobial peptide expression distinguishes Alzheimer’s disease from normal agingMin Wang, I‐Feng Peng, Simin Li, Xianda Hu · 2020 · Aging
- Harnessing Immune Rejuvenation: Advances in Overcoming T Cell Senescence and Exhaustion in Cancer ImmunotherapyTesfahun Dessale Admasu, John S. Yu · 2025 · Aging Cell
- Association between age and repair of oxidatively damaged DNA in human peripheral blood mononuclear cellsMille Løhr, Annie Jensen, Louise Eriksen, Morten Grønbæk, Steffen H Loft, Peter Möller · 2015 · Mutagenesis
- Dietary Animal Plasma Proteins Improve the Intestinal Immune Response in Senescent MiceLluïsa Miró, Alba Garcia-Just, Concepció Amat, Javier Polo, Miquel Moretó, Anna Pérez‐Bosque · 2017 · Nutrients
- A Mathematical Model of the Dynamics of Cytokine Expression and Human Immune Cell Activation in Response to the Pathogen Staphylococcus aureusKian Talaei, Steven Andrew Garan, Bárbara de Melo Quintela, Mette Sofie Olufsen, Hyong Jin Cho, Julia R. Jahansooz, Puneet K. Bhullar, Elliott K. Suen, Walter Piszker, Nuno Martins et al. · 2021 · Frontiers in Cellular and Infection Microbiology
- Tracking the evolution of anti-SARS-CoV-2 antibodies and long-term humoral immunity within 2 years after COVID-19 infectionMariam Movsisyan, Nune Truzyan, Irina Kasparova, Armine S. Chopikyan, Ra’ed Sawaqed, Alexandra Bedross, Meline Sukiasyan, Karen Dilbaryan, Sanobar Shariff, Burhan Kantawala et al. · 2024 · Scientific Reports
- Precious2GPT: the combination of multiomics pretrained transformer and conditional diffusion for artificial multi-omics multi-species multi-tissue sample generationDenis Sidorenko, Stefan Pushkov, Akhmed Sakip, Geoffrey Ho Duen Leung, Sarah Wing Yan Lok, Anatoly Urban, Diana Zagirova, Alexander Veviorskiy, Nina Tihonova, Aleksandr Kalashnikov et al. · 2024 · npj Aging
- Innate immunity dysregulation in aging eye and therapeutic interventionsSusmita Das, Zeeshan Ahmad, Amol S. Suryawanshi, Ashok Kumar · 2022 · Ageing Research Reviews
- Learning from Persistent Viremia: Mechanisms and Implications for Clinical Care and HIV-1 CureFengting Wu, Francesco Roberto Simonetti · 2023 · Current HIV/AIDS Reports
- Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarityAnastasia A. Latanova, Stefan Petkov, Athina Kilpeläinen, Juris Jansons, Oleg Latyshev, Yulia V. Kuzmenko, Jorma Hinkula, Maxim A. Abakumov, Валуев-Эллистон Владимир Треворович, Mark Gomelsky et al. · 2018 · Scientific Reports
- Proteodynamics in aging human T cells – The need for its comprehensive study to understand the fine regulation of T lymphocyte functionsJacek Maciej Witkowski, Anna Mikosik, Ewa Bryl, Tamàs Fülöp · 2017 · Experimental Gerontology
- TP53INP1 deficiency maintains murine B lymphopoiesis in aged bone marrow through redox-controlled IL-7R/STAT5 signalingBochra Zidi, Christelle Vincent‐Fabert, Laurent Pouyet, Marion Seillier, Amelle Vandevelde, Prudence N’guessan, Mathilde Poplineau, Geoffrey C. Guittard, Stéphane J.C. Mancini, Estelle Duprez et al. · 2018 · Proceedings of the National Academy of Sciences
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cellsAmbika Verma, Gohar Azhar, Pankaj Patyal, Wei Zhang, Xiaomin Zhang, Jeanne Y. Wei · 2024 · GeroScience
- Older adults: panoramic view on the COVID-19 vaccinationBoris Georgievich Andryukov, Natalya N. Besednova · 2021 · AIMS Public Health
- Patho-Physiology of Aging and Immune-Senescence: Possible Correlates With Comorbidity and Mortality in Middle-Aged and Old COVID-19 PatientsSaba Farheen, Sudhanshu Agrawal, Swaleha Zubair, Anshu Agrawal, Fauzia Jamal, Ishrat Altaf, Abu Kashif Anwar, Syed Mohammad Umair, Mohammad Owais · 2021 · Frontiers in Aging
- Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model miceXiaoyan Li, Haifeng Ye, Tie Su, Chuan Hu, Yao-Qi Huang, Xinxin Fu, Zhisheng Zhong, Xuelian Du, Yuehui Zheng · 2023 · Frontiers in Immunology
- Genes involved in immunity and apoptosis are associated with human presbycusis based on microarray analysisDong Yang, Ming Li, Puzhao Liu, Haiyan Song, Yuping Zhao, Jianrong Shi · 2014 · Acta Oto-Laryngologica
- Aging on a different scale – chronological versus pathology-related agingJoost P.M. Melis, Martijs J. Jonker, Jan Vijg, Jan H.J. Hoeijmakers, Timo M. Breit, Harry VAN STEEG · 2013 · Aging
- T-Cell Responses in Adults During Natural Respiratory Syncytial Virus InfectionDavid Roumanes, Ann Regina Falsey, Sally A. Quataert, Shelley Secor‐Socha, F E-H Lee, Hongmei Yang, Sanjukta Bandyopadhyay, Jeanne Holden‐Wiltse, David J. Topham, Edward E. Walsh · 2018 · The Journal of Infectious Diseases
- Ghrelin Signaling in Immunometabolism and Inflamm-AgingChuo Fang, Hang Xu, Shaodong Guo, Susanne U. Mertens‐Talcott, Yuxiang Sun · 2018 · Advances in experimental medicine and biology
- DNA methylation ageing clocks and pancreatic cancer risk: pooled analysis of three prospective nested case-control studiesMei Chung, Mengyuan Ruan, Naisi Zhao, Devin C. Koestler, Immaculata De Vivo, Karl T. Kelsey, Dominique S. Michaud · 2020 · Epigenetics
- Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant MiceAna Reis-Mendes, José Luís Dores‐Sousa, Ana Isabel Padrão, Margarida Duarte‐Araújo, José Alberto Duarte, Vítor Seabra, Salomé Gonçalves‐Monteiro, Fernando Remião, Félix Dias Carvalho, Emı́lia Sousa et al. · 2021 · Pharmaceuticals
- Aging phenotype in AD brain organoids: Track to success and challengesMuhammad Kamal Hossain, Hyung‐Ryong Kim, Han–Jung Chae · 2024 · Ageing Research Reviews
- Hyperbaric oxygen therapy: future prospects in regenerative therapy and anti-agingManoj Gupta, Jaishriram Rathored · 2024 · Frontiers in Aging
- Age and rest–activity rhythm as predictors of survival in patients with newly diagnosed lung cancerWen‐Pei Chang, Robert David Smith, Chia‐Chin Lin · 2017 · Chronobiology International
- Relationship between senescence in macaques and bone marrow mesenchymal stem cells and the molecular mechanismXinghua Pan, Yuhao Chen, Yu-Kun Yang, Xuejuan Zhang, Qing-Keng Lin, Zi‐An Li, Xuemin Cai, Rongqing Pang, Xiangqing Zhu, Guang‐Ping Ruan · 2019 · Aging
- Endothelin-1-mediated miR-let-7g-5p triggers interlukin-6 and TNF-α to cause myopathy and chronic adipose inflammation in elderly patients with diabetes mellitusChung-Huang Tsai, Pei‐Ju Huang, Lee It, Chien‐Min Chen, Min Huan Wu · 2022 · Aging
- Cardiac iron metabolism during aging – Role of inflammation and proteolysisSophia Walter, Christina Mertens, Martina Ulrike Muckenthaler, Christiane Ott · 2023 · Mechanisms of Ageing and Development
- Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsisLaura Kuchler, Lisa Katharina Sha, Annika Klara Giegerich, Tilo Knape, Carlo Angioni, Nerea Ferreirós, Martina V. Schmidt, Andreas Weigert, Bernhard Brüne, Andreas von Knethen · 2017 · Molecular Immunology
- Expansion of Activated Memory CD4+ T Cells Affects Infectivity of CCR5-Tropic HIV-1 in Humanized NOD/SCID/JAK3null MiceKazutaka Terahara, Masayuki Ishige, Shota Ikeno, Yu-ya Mitsuki, Seiji Okada, Kazuo Kobayashi, Yasuko Tsunetsugu‐Yokota · 2013 · PLoS ONE
- The long pentraxin PTX3: a novel serum marker to improve the prediction of osteoporosis and osteoarthritis bone-related phenotypesVirginia Veronica Visconti, Chiara Greggi, Simona Fittipaldi, Donato Casamassima, Mariagrazia Tallarico, Francesco Romano, Annalisa Botta, Umberto Tarantino · 2021 · Journal of Orthopaedic Surgery and Research
- How Can We Improve the Vaccination Response in Older People? Part II: Targeting Immunosenescence of Adaptive Immunity CellsMaider Garnica, Anna Aiello, Mattia Emanuela Ligotti, Giulia Accardi, Hugo Arasanz, Ana Bocanegra, Ester Blanco, Anna Calabrò, Luisa Chocarro, Miriam Echaide et al. · 2022 · International Journal of Molecular Sciences
- Traumatic Brain Injury, Sleep, and Melatonin—Intrinsic Changes with Therapeutic PotentialAllen Bell, Bryson Hewins, Courtney Bishop, Amanda H. Fortin, Jonathan Wang, Jennifer L. Creamer, Jacob F. Collen, J. Kent Werner · 2023 · Clocks & Sleep
- Tenofovir-Based Highly Active Antiretroviral Therapy Is Associated with Superior CD4 T Cells Repopulation Compared to Zidovudine-Based HAART in HIV 1 Infected AdultsVitus Sambo Badii, Kwame Ohene Buabeng, Thomas Agyarko‐Poku, Arnold Donkor Forkuo, Bright Boafo Boamah, Stephen Mensah Arhin, Daniel Edem Kpewou · 2018 · International Journal of Chronic Diseases
- Six weeks of strength endurance training decreases circulating senescence-prone T-lymphocytes in cytomegalovirus seropositive but not seronegative older womenHung Cao Dinh, Ivan Bautmans, Ingo Beyer, Oscar Okwudiri Onyema, Keliane Liberman, Liza De Dobbeleer, Wim Renmans, Sam Vander Meeren, Kristin Jochmans, Andreas Delaere et al. · 2019 · Immunity & Ageing
- Immunosenescence Inventory—a multi-omics database for immune aging researchHao Li, Wei Zhao, Fei Yang, Qin Qiao, Shuai Ma, Kuan Yang, Shuhui Song, Si Wang, Jing Tao Qu, Guang‐Hui Liu et al. · 2024 · Nucleic Acids Research
- Reproductive effort alters immune parameters measured post‐partum in European rabbits under semi‐natural conditionsHeiko G. Rödel, Manuela Zapka, Volker Stefanski, Dietrich von Holst · 2016 · Functional Ecology
- COVID-19, rheumatic diseases and immune dysregulation—a perspectiveShahna Tariq, Charmaine van Eeden, Jan Willem Cohen Tervaert, Mohammed S. Osman · 2021 · Clinical Rheumatology
- A new insight into cell biological and biochemical changes through agingSomayeh Sahabi, Davoud Jafari-Gharabaghlou, Nosratollah Zarghami · 2022 · Acta Histochemica
- Proteostasis in T cell agingA. Elisabeth Gressler, Houfu Leng, Heidi Zinecker, Anna Katharina Simon · 2023 · Seminars in Immunology
- Plasma levels of soluble HLA‐G and cytokines in papillary thyroid carcinoma before and after thyroidectomyBruna C. Bertol, Jéssica Nayara Góes de Araújo, Ibrahim Abiodoun Sadissou, Paulin Sonon, Fabrício C. Dias, Raul Hernandes Bortolin, Nathalie L. de Figueiredo-Feitosa, Luiz Carlos Conti de Freitas, Sheila Ramos de Miranda Henriques Tarrapp, Carlos César de Oliveira Ramos et al. · 2020 · International Journal of Clinical Practice
- The expression and function of growth hormone secretagogue receptor in immune cells: A current perspectiveJi Yeon Noh, Matthew Herrera, Bhimanagouda S. Patil, Xiao‐Di Tan, Gus A. Wright, Yuxiang Sun · 2022 · Experimental Biology and Medicine
- The interplay of senescence and MMPs in myocardial infarction: implications for cardiac aging and therapeuticsAshok Kumar Balaraman, Abdulmalik Saleh Alfawaz Altamimi, Marianesan Arockia Babu, Kavita Goyal, Gopalakrishnan Padmapriya, Pooja Bansal, Sumit Rajotiya, Mohit Kumar, Pranchal Rajput, Mohd Imran et al. · 2025 · Biogerontology
- Role of Melatonin in Angiotensin and AgingAhmet Özer Şehirli, Serkan Sayıner, Ugochukwu Chukwunyere, Nedime Serakıncı · 2021 · Molecules
- Strategies to make human skin models based on cellular senescence for ageing researchZinaida Shakel, Sofia A. Costa Lima, Salette Reis · 2024 · Ageing Research Reviews
- Aspergillus osteomyelitis of the lumbar spine complicated with orbital apex syndrome: A potential role of the Batson's plexus in disease propagationJosé F. Camargo, Vimon Seriburi, Michael S. Tenner, Marc Y. El Khoury · 2012 · Medical Mycology Case Reports
- Expression of lymphocyte-derived growth hormone (GH) and GH-releasing hormone receptors in aging ratsDouglas A. Weigent · 2013 · Cellular Immunology
- Compensatory increase in USP14 activity accompanies impaired proteasomal proteolysis during agingSubramaniam Ponnappan, Michela Palmieri, Dennis H. Sullivan, Usha Ponnappan · 2013 · Mechanisms of Ageing and Development
- Comparative Transcriptomics Reveals Patterns of Adaptive Evolution Associated with Depth and Age Within Marine Rockfishes (Sebastes)Joseph Heras, Andres Aguilar · 2018 · Journal of Heredity
- Recurrent bladder cancer in aging societies: Importance of major histocompatibility complex class I antigen presentationEdyta Wieczorek, Malgorzata Anna Garstka · 2020 · International Journal of Cancer
- Immunotherapy use in older adults with cancer with frailty: A young SIOG review paperDeniz Can Güven, Bertha Alejandra Martínez-Cannon, Giuseppe Dario Testa, Janine Capobiango Martins, Rogelio Velasco, Tania Kalsi, Fábio Gomes · 2024 · Journal of Geriatric Oncology
- Mechanisms and strategies of immunosenescence effects on non-small cell lung cancer (NSCLC) treatment: A comprehensive analysis and future directionsHuatao Zhou, Zilong Zheng, Chengming Fan, Zijing Zhou · 2025 · Seminars in Cancer Biology
- Porphyromonas gingivalis-Lipopolysaccharide Induced Caspase-4 Dependent Noncanonical Inflammasome Activation Drives Alzheimer’s Disease PathologiesAmbika Verma, Gohar Azhar, Pankaj Patyal, Xiaomin Zhang, Jeanne Y. Wei · 2025 · Cells
- Role of Adaptive Immune and Impacts of Risk Factors on Adaptive Immune in Alzheimer’s Disease: Are Immunotherapies Effective or Off-Target?Mingchao Shi, Fengna Chu, Xiaoping Tian, Qiaolifan Aerqin, Feiqi Zhu, Jie Zhu · 2021 · The Neuroscientist
- Impairment of non-muscle myosin IIA in human CD4+ T cells contributes to functional deficits in the elderlyStefania Canè, Subramaniam Ponnappan, Usha Ponnappan · 2011 · Cellular and Molecular Immunology
- Regulation of cardiac fibroblasts by lymphocytes after a myocardial infarction: playing in the major leagueMaya Learmonth, Alexa Corker, Shaoni Dasgupta, Kristine Y. DeLeon‐Pennell · 2023 · American Journal of Physiology-Heart and Circulatory Physiology
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- Prevalence of human herpesvirus-8 among HIV-infected patients, intravenous drug users and the general population in IranRezvan Kakavand‐Ghalehnoei, Zabihollah Shoja, Alireza Najafi, Mostafa Haji Molla Hoseini, Shohreh Shahmahmoodi, Sayed Mahdi Marashi, Ahmad Nejati, Somayeh Jalilvand · 2016 · Sexual Health
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- Mitochondrial Oxidative Stress Regulates FOXP3+ T-Cell Activity and CD4-Mediated Inflammation in Older Adults with FrailtyJappreet Singh Gill, Benu Bansal, Kai Guo, Fang Huang, Harpreet Singh, Junguk Hur, M. Nadeem Khan, Ramkumar Mathur · 2024 · International Journal of Molecular Sciences
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