The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.
Production and Physiological Effects of Hydrogen Sulfide
Open accessAbstract
SIGNIFICANCE: Hydrogen sulfide (H2S) has been recognized as a physiological mediator with a variety of functions. It regulates synaptic transmission, vascular tone, inflammation, transcription, and angiogenesis; protects cells from oxidative stress and ischemia-reperfusion injury; and promotes healing of ulcers. RECENT ADVANCES: In addition to cystathionine β-synthase and cystathionine γ-lyase, 3-mercaptopyruvate sulfurtransferase along with cysteine aminotransferase was recently demonstrated to produce H2S. Even in bacteria, H2S produced by these enzymes functions as a defense against antibiotics, suggesting that the cytoprotective effect of H2S is a universal defense mechanism in organisms from bacteria to mammals. CRITICAL ISSUES: The functional form of H2S-undissociated H2S gas, dissociated HS ion, or some other form of sulfur-has not been identified. FUTURE DIRECTIONS: The regulation of H2S production by three enzymes may lead to the identification of the physiological signals that are required to release H2S. The identification of the physiological functions of other forms of sulfur may also help understand the biological significance of H2S.
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Furchgott, R. F., & Zawadzki, J. V. (1980) · Nature · doi:10.1038/288373a0 · Cited by 12,064
Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme.
Bredt, D. S., & Snyder, S. H. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.2.682 · Cited by 3,284
Garthwaite, J., Charles, S. L., & Chess-Williams, R. (1988) · Nature · doi:10.1038/336385a0 · Cited by 2,549
The possible role of hydrogen sulfide as an endogenous neuromodulator
Abe, K., & Kimura, H. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-03-01066.1996 · Cited by 2,239
Self-citationSensors and regulators of intracellular pH
Casey, J. R., Grinstein, S., & Orlowski, J. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2820 · Cited by 2,218
The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener
Zhao, W. (2001) · The EMBO Journal · doi:10.1093/emboj/20.21.6008 · Cited by 1,936
Ionic dependence of glutamate neurotoxicity
Choi, D. (1987) · The Journal of Neuroscience · doi:10.1523/jneurosci.07-02-00369.1987 · Cited by 1,802
Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Cycle or a Double-Edged Sword?
Malhotra, J. D., & Kaufman, R. J. (2007) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1782 · Cited by 1,563
Elrod, J. W., Calvert, J. W., Morrison, J., Doeller, J. E., Kraus, D. W., Tao, L., Jiao, X., Scalia, R., Kiss, L., Szabo, C., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705891104 · Cited by 1,255
Self-citationHosoki, R., Matsuki, N., & Kimura, H. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6878 · Cited by 1,218
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Szabo, C., Ransy, C., Módis, K., Andriamihaja, M., Murghes, B., Coletta, C., Olah, G., Yanagi, K., & Bouillaud, F. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12369 · Cited by 440
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Cortese-Krott, M. M., Fernandez, B. O., Santos, J. L. T., Mergia, E., Grman, M., Nagy, P., Kelm, M., Butler, A., & Feelisch, M. (2014) · Redox Biology · doi:10.1016/j.redox.2013.12.031 · Cited by 153
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González Dalmasy, J. M., Fitzsimmons, C. M., Frye, W. J. E., Perciaccante, A. J., Jewell, C. P., Jenkins, L. M., Batista, P. J., Robey, R. W., & Gottesman, M. M. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.110989 · Cited by 3
Metadata
- Authors
- Kimura, H.
- Venue
- Antioxidants & Redox Signaling
- Publisher
- SAGE Publications
- Published
- 2014-02-10
- Volume
- 20
- Issue
- 5
- Pages
- 783-793
- ISSN
- 1523-0864 (ISSN-L)
- 1557-7716
- OpenAlex
- W2024355544
- Cited by
- 347
- References
- 78
- FWCI
- 8.71
- Type
- journal article
- Language
- en
- Open access
- green
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