CoChat
Sign Up
Cited by 36Diabetes Management and ResearchDiet, Metabolism, and DiseaseDiabetes, Cardiovascular Risks, and Lipoproteins

Effects of different proportion of carbohydrate in breakfast on postprandial glucose excursion in normal glucose tolerance and impaired glucose regulation subjects

Open access
Kang, Xin, Wang, Chun, Lifang, Lv, Chen, Dawei, Yang, Yanzhi, Liu, Guanjian, Wen, Hu, Chen, Lihong +5 more·2013·Diabetes Technology & Therapeutics
DOI 10.1089/dia.2012.0305PMC PMC3709592
Open this paper in CoChat — free account

Abstract

BACKGROUND: The variability of postprandial plasma glucose is an independent risk factor for diabetes. The type and amount of carbohydrate may be important determinants of glycemic control. The aim of the study was to compare the effects of different proportions of carbohydrate in breakfast on postprandial blood glucose fluctuations in impaired glucose regulation (IGR) and normal glucose tolerance (NGT) subjects. SUBJECTS AND METHODS: This is a cross-sectional study of two groups including 55 subjects with IGR and 78 individuals with NGT. Their recorded breakfast was sorted into low-carbohydrate (LC) (carbohydrate <45%), medium-carbohydrate (MC) (carbohydrate 45-65%), and high-carbohydrate (HC) (carbohydrate >65%) meals according to the proportion of carbohydrate. Glucose concentrations were continuously measured with a continuous glucose monitoring system, and parameters such as the incremental area under the curve (iAUC) of glucose and postprandial glucose excursion (PPGE) were calculated to evaluate postprandial glucose fluctuations. RESULTS: The postprandial fluctuations of glucose increased gradually with increased proportions of carbohydrate in breakfast in both IGR and NGT subjects. For the MC and HC meals, iAUC, PPGE, postprandial glucose spike (PGS), and mean blood glucose were significantly greater than those in the NGT group (P<0.05), respectively. The median time to PGS and the time period in which glucose concentrations decreased to baseline after the MC and HC meals in the IGR group were significantly longer than those in the NGT group (P<0.01), respectively. Compared with the NGT subjects for the HC meal, the IGR subjects consuming the MC meal had greater PGS, range of glucose concentrations, SD, and PPGE (P<0.05). CONCLUSIONS: The proportion of carbohydrate in breakfast contributes to glucose excursions in the NGT and IGR subjects. In the IGR subjects, a HC meal should be avoided and a LC meal should be recommended to prevent development of diabetes.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1089/dia.2012.0305

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Limiting the readily available carbohydrates in breakfast and replacing them with other energy and nutrient sources may be beneficial for achieving better glucose regulation and lower glycemic excursions.

    “Thus, limiting the readily available carbohydrates in breakfast and replacing them with other energy and nutrient sources may be beneficial for achieving better glucose regulation and lower glycemic excursions [84].”

    From Effects of diet, lifestyle, Chrononutrition and alternative dietary interventions on postprandial Glycemia and insulin resistance (2022) · cites this paper as [84]

  • Short- and long-term clinical trials in subjects with T2DM suggested that consuming more lower fat containing proteins than carbohydrates at breakfast help to reduce postprandial hyperglycemia, insulin responses and blood lipids.

    “Short- and long-term clinical trials in subjects with T2DM [84,296,297,298,299,300] (Table 2 and Table 3) suggested that consuming more lower fat containing proteins than carbohydrates at breakfast help to reduce postprandial hyperglycemia, insulin responses and blood lipids.”

    From Effects of diet, lifestyle, Chrononutrition and alternative dietary interventions on postprandial Glycemia and insulin resistance (2022) · cites this paper as [84]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 1

  1. [18]Yuexin Yang., editor. Institute of Nutrition and Food Safety, Chinese Center for Disease Control and Prevention. China Food Composition (2004) Book 2. Beijing: Peking University Medical Press; 2004. [Google Scholar]

Cited by

Sorted by citations

Related

Authors
Kang, X., Wang, C., Lifang, L., Chen, D., Yang, Y., Liu, G., Wen, H., Chen, L., He, L., Li, X., Tian, H., Jia, W., & Ran, X.
Affiliations
  • Sichuan University (CN)
  • Shanghai Jiao Tong University (CN)
Corresponding author
Ran, Xingwu
ORCID
Venue
Diabetes Technology & Therapeutics
Publisher
SAGE Publications
Published
2013-07
Volume
15
Issue
7
Pages
569-574
ISSN
  • 1520-9156 (ISSN-L)
  • 1557-8593
DOI
10.1089/dia.2012.0305
PMC
PMC3709592
OpenAlex
W1971082281
Cited by
36
References
26
Citations by year
2026: 3 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 10 · 2021: 3 · 2020: 2 · 2019: 6 · 2018: 1 · 2017: 2 · 2016: 1 · 2015: 2 · 2014: 1
FWCI
1.05
Type
journal article
Language
en
Open access
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations
  • Diabetes Technology & Therapeutics (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
postprandial glucose excursions, prediabetes, normal glucose tolerance, continuous glucose monitoring, glycemic variability, low-carbohydrate diet, diabetes prevention
MeSH terms
Adult, Aged, China, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Dietary Carbohydrates, Female, Glucose, Humans, Kinetics, Male, Middle Aged, Prediabetic State, Risk Factors, Glucose Intolerance, Monitoring, Ambulatory, Postprandial Period, Extracellular Fluid, Diet, Carbohydrate-Restricted, Young Adult, Breakfast

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review