The Canadian LMC Diabetes Registry: A Profile of the Demographics, Management, and Outcomes of Individuals with Type 1 Diabetes
Open accessAbstract
Objective: Clinical guidelines now define the standard of diabetes care, but few health care jurisdictions systematically assess their practicality and impact. The Canadian LMC Diabetes Registry includes the electronic health records of >50 endocrinologists in three provinces and provides quarterly real-time outcome reports to each endocrinologist. This retrospective cohort study aimed to characterize the demographics, treatment regimens, and outcomes of the type 1 diabetes (T1D) patient population in the registry. Research Design and Methods: Adults were included if they had a clinical diagnosis of T1D, had seen an LMC endocrinologist between July 1, 2015 and June 30, 2018, and had follow-up >6 months. This study is registered on clinicaltrials.gov (NCT04162067). Results: The resulting cohort included 3600 individuals with mean age of 43.9 ± 15.3 years and duration of diabetes of 21.5 ± 13.9 years. Mean hemoglobin A1C (HbA1c) was 8.1% ± 1.5% and only 22.5% had achieved HbA1c ≤7.0%. In each measure, individuals in younger cohorts showed poorer glycemic control than older cohorts. Within each age cohort, insulin pump users showed a lower mean HbA1c than those using multiple daily injections, especially in cohorts who were also not using a continuous glucose monitor. Overall, 63.1% reported at least weekly hypoglycemia, whereas 3.6% reported severe hypoglycemia ≥1 per year. Conclusions: Despite receiving care in an advanced well-resourced environment, within a public health car…
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Fewer than one-half of adults with T1D currently meet recommended HbA1c targets (generally <7.0%).
“Given that fewer than one‐half of adults with type 1 diabetes (T1D) currently meet recommended HbA1c targets (generally <7.0%), diabetes technologies are important tools for improving glycaemic outcomes while reducing diabetes burden.”
Cites
Battelino, T., Danne, T., Bergenstal, R. M., Amiel, S. A., Beck, R., Biester, T., Bosi, E., Buckingham, B. A., Cefalu, W. T., Close, K. L., et al. (2019) · Diabetes Care · doi:10.2337/dci19-0028 · Cited by 4,032 · cited 1× · see citing works
“27 As seen in the other real-world reports, CGM/FGM users in this cohort showed no difference in glycemia between individuals using MDI versus CSII therapy.”
State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016–2018
Foster, N. C., Beck, R. W., Miller, K. M., Clements, M. A., Rickels, M. R., DiMeglio, L. A., Maahs, D. M., Tamborlane, W. V., Bergenstal, R., Smith, E., et al. (2019) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2018.0384 · Cited by 1,907 · see citing works
Fung, C. H., Lim, Y.-W., Mattke, S., Damberg, C. L., & Shekelle, P. (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-2-200801150-00006 · Cited by 981 · see citing works
DiMeglio, L. A., Acerini, C. L., Codner, E., Craig, M. E., Hofer, S. E., Pillay, K., & Maahs, D. M. (2018) · Pediatric Diabetes · doi:10.1111/pedi.12737 · Cited by 604 · see citing works
Miller, K. M., Beck, R. W., Bergenstal, R. M., Goland, R. S., Haller, M. J., McGill, J. B., Rodriguez, H., Simmons, J. H., Hirsch, I. B., & for the T1D Exchange Clinic Network (2013) · Diabetes Care · doi:10.2337/dc12-1770 · Cited by 505 · see citing works
Yeh, H.-C., Brown, T. T., Maruthur, N., Ranasinghe, P., Berger, Z., Suh, Y. D., Wilson, L. M., Haberl, E. B., Brick, J., Bass, E. B., et al. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-157-5-201209040-00508 · Cited by 493 · see citing works
The relationships between time in range, hyperglycemia metrics, and HbA1c
Beck, R. W., Bergenstal, R. M., Cheng, P., Kollman, C., Carlson, A. L., Johnson, M. L., & Rodbard, D. (2019) · Journal of Diabetes Science and Technology · doi:10.1177/1932296818822496 · Cited by 479 · see citing works
The relationship of hemoglobin A1C to time-in-range in patients with diabetes
Vigersky, R. A., & McMahon, C. (2019) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2018.0310 · Cited by 464 · see citing works
The T1D exchange clinic registry
Beck, R. W., Tamborlane, W. V., Bergenstal, R. M., Miller, K. M., DuBose, S. N., Hall, C. A., & for the T1D Exchange Clinic Network (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-1561 · Cited by 456 · see citing works
Livingstone, S. J., Looker, H. C., Hothersall, E. J., Wild, S. H., Lindsay, R. S., Chalmers, J., Cleland, S. J., Leese, G., McKnight, J. A., Morris, A. D., et al. (2012) · PLoS Medicine · doi:10.1371/journal.pmed.1001321 · Cited by 347 · see citing works
McKnight, J. A., Wild, S. H., Lamb, M. J. E., Cooper, M. N., Jones, T. W., Davis, E. A., Hofer, S., Fritsch, M., Schober, E., Svensson, J., et al. (2015) · Diabetic Medicine · doi:10.1111/dme.12676 · Cited by 343 · see citing works
Introduction: Standards of Medical Care in Diabetes—2019
Frías, J. P. (2018) · Diabetes Care · doi:10.2337/dc19-sint01 · Cited by 331 · see citing works
7. Diabetes Technology: <i>Standards of Medical Care in Diabetes—2019</i>
American Diabetes Association (2019) · Diabetes Care · doi:10.2337/dc19-s007 · Cited by 179 · see citing works
Miller, K. M., Beck, R. W., Foster, N. C., Maahs, D. M., & Exchange, F. T. T. (2020) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2019.0393 · Cited by 162 · see citing works
Chung, H. S., Lee, M. J., Hwang, S. Y., Lee, H. J., Yoo, H. J., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., Choi, D. S., et al. (2016) · Cardiovascular Diabetology · doi:10.1186/s12933-015-0324-y · Cited by 129 · see citing works
Diabetes care – improvement through measurement
Eliasson, B., & Guðbjörnsdóttir, S. (2014) · Diabetes Research and Clinical Practice · doi:10.1016/s0168-8227(14)70732-6 · Cited by 128 · see citing works
Šoupal, J., Petruželková, L., Flekač, M., Pelcl, T., Matoulek, M., Daňková, M., Škrha, J., Svačina, Š., & Prázný, M. (2016) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2016.0171 · Cited by 126 · see citing works
Benkhadra, K., Alahdab, F., Tamhane, S. U., McCoy, R. G., Prokop, L. J., & Murad, M. H. (2017) · Endocrine · doi:10.1007/s12020-016-1039-x · Cited by 113 · see citing works
Charalampopoulos, D., Hermann, J. M., Svensson, J., Skrivarhaug, T., Maahs, D. M., Åkesson, K., Warner, J., Holl, R. W., Birkebæk, N., Drivvoll, A. K., et al. (2018) · Diabetes Care · doi:10.2337/dc17-2271 · Cited by 104 · see citing works
Grabert, M., Schweiggert, F., & Holl, R. W. (2002) · Computer Methods and Programs in Biomedicine · doi:10.1016/s0169-2607(02)00035-4 · Cited by 85 · see citing works
Engström, M. S., Leksell, J. K., Johansson, U., Borg, S., Palaszewski, B., Franzén, S., Guðbjörnsdóttir, S., & Eeg‐Olofsson, K. (2019) · Health and Quality of Life Outcomes · doi:10.1186/s12955-019-1212-z · Cited by 72 · see citing works
Aronson, R., Orzech, N., Ye, C., Goldenberg, R., & Brown, V. (2015) · Journal of Diabetes · doi:10.1111/1753-0407.12257 · Cited by 39 · see citing works
Self-citationSchwandt, A., Best, F., Biester, T., Grünerbel, A., Kopp, F., Krakow, D., Laimer, M. W., Wagner, C., Holl, R. W., & initiative, O. B. O. T. D. (. (2017) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.2908 · Cited by 32 · see citing works
Pettus, J., Zhou, F. L., Shepherd, L. C., Mercaldi, K., Preblick, R., Hunt, P. R., Paranjape, S., Miller, K. M., & Edelman, S. V. (2019) · Diabetes Obesity and Metabolism · doi:10.1111/dom.13937 · Cited by 30 · see citing works
Boulet, G., Halpern, E. M., Lovblom, L. E., Weisman, A., Bai, J.-W., Eldelekli, D., Keenan, H. A., Brent, M. H., Paul, N., Bril, V., et al. (2016) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2015.0216 · Cited by 26 · see citing works
Danne, T., Kaltheuner, M., Koch, A., Ernst, S., Rathmann, W., Rüssmann, H.-J., Bramlage, P., & Studiengruppe, F. D. D. (2013) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-0033-1343144 · Cited by 25 · see citing works
Aronson, R., Orzech, N., Ye, C., Brown, R. E., Goldenberg, R., & Brown, V. (2016) · Diabetes Care · doi:10.2337/dc15-2666 · Cited by 23 · see citing works
Self-citationvan Mark, G., Lanzinger, S., Barion, R., Degenhardt, M., Badis, S., Noll, H., Danne, T., Bramlage, P., Seufert, J., & Holl, R. W. (2019) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/2042018819830867 · Cited by 22 · see citing works
Willers, C., Iderberg, H., Axelsen, M., Dahlström, T., Julin, B., Leksell, J. K., Lindberg, A., Lindgren, P., Muth, K. L., Svensson, A., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0199170 · Cited by 21 · see citing works
(2018) · Canadian Journal of Diabetes · doi:10.1016/s1499-2671(18)30886-4 · Cited by 14 · see citing works
Aronson, R., Li, A., Brown, R. E., Walker, A., Lyons, A., & Orzech, N. (2019) · Diabetes Care · doi:10.2337/dc19-0699 · Cited by 11 · see citing works
Self-citationThe Australasian diabetes data network (ADDN): first steps towards a national database resource
Phelan, H., Donaghue, K. C., Cameron, F. J., Clapin, H. F., Cotterill, A. M., Couper, J., Craig, M. E., Davis, E. A., Jefferies, C., Tham, E., et al. (2015) · International Journal of Pediatric Endocrinology · doi:10.1186/1687-9856-2015-s1-o35 · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Brazeau, A., Messier, V., Talbo, M. K., Gagnon, C., Taleb, N., Fortier, I., Wu, Z., Perkins, B. A., Carpentier, A. C., Bandini, A., et al. (2022) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2022.05.010 · Cited by 54 · see citing works
Shilo, S., Godneva, A., Rachmiel, M., Korem, T., Kolobkov, D. S., Karady, T., Bar, N., Wolf, B. C., Glantz-Gashai, Y., Cohen, M., et al. (2021) · Diabetes Care · doi:10.2337/dc21-1048 · Cited by 42 · see citing works
Rotondi, M. A., Wong, O. C. Y., Riddell, M. C., & Perkins, B. A. (2022) · Diabetes Care · doi:10.2337/dc21-2341 · Cited by 24 · see citing works
Noor, N., Ebekozien, O. A., Levin, L., Stone, S. L., Sparling, D. P., Rapaport, R., & Maahs, D. M. (2021) · Diabetes Care · doi:10.2337/dc21-0074 · Cited by 23 · see citing works
Mousavi, S., Greenberg, D. T., Ndjaboué, R., Greiver, M., Drescher, O., Dansokho, S. C., Boutin, D., Chouinard, J.-M., Dostie, S., Fenton, R., et al. (2023) · JMIR Diabetes · doi:10.2196/35682 · Cited by 17 · see citing works
Strategically Playing with Fire: SGLT Inhibitors as Possible Adjunct to Closed-Loop Insulin Therapy
Pasqua, M., Tsoukas, M. A., & Haidar, A. (2021) · Journal of Diabetes Science and Technology · doi:10.1177/19322968211035411 · Cited by 15 · see citing works
Brown, R. E., Chu, L., Norman, G. J., & Abitbol, A. (2022) · Diabetic Medicine · doi:10.1111/dme.14937 · Cited by 13 · see citing works
Self-citationRodbard, D., & Garg, S. K. (2021) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2021.0030 · Cited by 13 · see citing works
Moreno-Fernández, J., Chico, A. I., Martínez‐Brocca, M. A., Beato-Víbora, P. I., Vidal, M., de la Piedra, M. A. C., Quirós, C., Muñoz‐Rodríguez, J. R., SPAIP Registry Study, López, A. A., et al. (2022) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2022.0207 · Cited by 9 · see citing works
Weisman, A., Brown, R., Chu, L., Aronson, R., & Perkins, B. A. (2024) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2023.09.001 · Cited by 8 · see citing works
Self-citationBrown, R. E., Vienneau, T. E., & Aronson, R. (2020) · Diabetic Medicine · doi:10.1111/dme.14420 · Cited by 8 · see citing works
Self-citationKhodabandehloo, P., Fakembe, P., Senga, J., Shulman, R., Lipscombe, L. L., Witteman, H. O., Banerjee, A., Presseau, J., Nakhla, M., Dogba, M. J., et al. (2025) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.16426 · Cited by 6 · see citing works
Achievement of treatment targets predicts progression of vascular complications in type 1 diabetes
Salna, I., Salna, E., Pahirko, L., Skrebinska, S., Krikova, R., Folkmane, I., Pīrāgs, V., & Sokolovska, J. (2021) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2021.108072 · Cited by 6 · see citing works
Talbo, M. K., RABASA-LHORET, R. P. R., Yale, J., Peters, T. M., & Brazeau, A. (2022) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2022.110080 · Cited by 6 · see citing works
Self-citationAlmazrouei, R. A., Sharma, C., Afandi, B. O., Aldahmani, K. M., Aburawi, E. H., Beshyah, S., ElGhazali, G. E., Yafei, Z. A., Al‐Rifai, R. H., & Alkaabi, J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0264545 · Cited by 6 · see citing works
Chan, K., Hansen, K., Muratov, S., Khoudigian-Sinani, S., & Lamotte, M. (2024) · Journal of Comparative Effectiveness Research · doi:10.57264/cer-2023-0124 · Cited by 5 · see citing works
Abitbol, A., & Chu, L. (2025) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16278 · Cited by 4 · see citing works
Self-citationWeisman, A., Booth, G. L., Everett, K., & TOMLINSON, G. A. (2024) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2024.0017 · Cited by 4 · see citing works
Boisvenue, J., Elezzabi, Y. A., Young, K., Gibson, K., Hinz, H., McClure, R. D., Homulos, R., Spiers, J. A., Senior, P. A., & Yeung, R. O. (2025) · Health Expectations · doi:10.1111/hex.70172 · Cited by 2 · see citing works
Pasqua, M., Odabassian, M., Tsoukas, M. A., & Haidar, A. (2023) · Journal of Diabetes Science and Technology · doi:10.1177/19322968231176302 · Cited by 2 · see citing works
Chu, L., & Abitbol, A. (2025) · Diabetic Medicine · doi:10.1111/dme.70119 · Cited by 1 · see citing works
Self-citationFilipczak, J., Żelazny, P., Sygacz, O., Bróż, S., Dankiewicz, S., Swora, A., Borowik, J., Brodowski, W., Pawłowski, P., Basta-Arciszewska, K., et al. (2022) · Journal of Education Health and Sport · doi:10.12775/jehs.2022.12.09.069 · Cited by 1 · see citing works
Mousavi, S., Greenberg, D. T., Ndjaboué, R., Greiver, M., Drescher, O., Dansokho, S. C., Boutin, D., Chouinard, J.-M., Dostie, S., Fenton, R., et al. (2021) · medRxiv · doi:10.1101/2021.12.14.21267759
Rotondi, M. A., Wong, O. C. Y., Riddell, M. C., & Perkins, B. A. (2022) · doi:10.2337/figshare.20173937.v1
Rotondi, M. A., Wong, O. C. Y., Riddell, M. C., & Perkins, B. A. (2022) · doi:10.2337/figshare.20173937
Improving Diabetes Care with the Omnipod → Automated Insulin System
Koong, X., Ng, N. C., Wong, R. S.-Y., Ong, T. Y. Y., Goh, B. H., & Ming, L. C. (2025) · International journal of clinical metabolism and diabetes. · doi:10.1177/30502071251357437
Genetic predisposition to autoimmune diabetes mellitus
Дворяньчиков, Я. В., Рамилевич, М. И., Лаптев, Д. Н., Khusainova, R. I., Shestakova, M., & Mokrysheva, N. G. (2026) · Acta Naturae · doi:10.32607/actanaturae.27704
- Authors
- Aronson, R., Brown, R. E., Abitbol, A., Goldenberg, R., Yared, Z., Ajala, B., & Yale, J.-F.
- Affiliations
- LMC Diabetes & Endocrinology (Canada) (CA)
- LMC Diabetes and Endocrinology, Toronto, Canada.
- Corresponding author
- Aronson, Ronnie
- Venue
- Diabetes Technology & Therapeutics
- Publisher
- SAGE Publications
- Published
- 2020-12-31
- Volume
- 23
- Issue
- 1
- Pages
- 31-40
- ISSN
- 1520-9156 (ISSN-L)
- 1557-8593
- OpenAlex
- W3042558568
- Cited by
- 27
- References
- 32
- Citations by year
- 2026: 1 · 2025: 5 · 2024: 2 · 2023: 3 · 2022: 9 · 2021: 6 · 2020: 1
- FWCI
- 3.59
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Diabetes Technology & Therapeutics (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- type 1 diabetes, diabetes management, glycemic control, HbA1c, insulin pump therapy, multiple daily insulin injections, continuous glucose monitoring, hypoglycemia, severe hypoglycemia, endocrinology practice, electronic health records, clinical practice guideline adherence
- MeSH terms
- Adult, Blood Glucose, Canada, Diabetes Mellitus, Type 1, Glycated Hemoglobin, Humans, Hypoglycemic Agents, Insulin, Middle Aged, Registries, Retrospective Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
