The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Toxicity of Cellulose Nanocrystals: A Review
Open accessAbstract
Cellulose nanocrystals (CNCs) are a biobased nanomaterial attracting increasing interest for a range of potential applications. This article reviews the current literature on the pulmonary, oral, dermal, and cytotoxicity of CNCs. Current studies of the oral and dermal toxicity of CNCs have shown a lack of adverse health effects, whereas studies of the pulmonary and cytotoxicity have yielded discordant results. Additional studies are needed to support the general conclusion that CNCs are nontoxic on ingestion or contact with the skin and to determine whether CNCs have adverse health effects on inhalation or elicit inflammatory or oxidative stress responses at the cellular level. This review underscores the importance of careful sample characterization and exclusion of interfering factors, such as the presence of endotoxins or toxic chemical impurities, for a detailed understanding of the potential adverse health effects of CNCs by various exposure routes.
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Cites
Cellulose nanomaterials review: structure, properties and nanocomposites
Moon, R. J., Martini, A., Nairn, J., Simonsen, J., & Youngblood, J. (2011) · Chemical Society Reviews · doi:10.1039/c0cs00108b · Cited by 6,756
Cellulose nanocrystals: chemistry, self-assembly, and applications
Habibi, Y., Lucia, L. A., & Rojas, O. J. (2010) · Chemical Reviews · doi:10.1021/cr900339w · Cited by 5,980
Beck-Candanedo, S., Roman, M., & Gray, D. G. (2005) · Biomacromolecules · doi:10.1021/bm049300p · Cited by 1,588
Self-citationCellulosic Bionanocomposites: A Review of Preparation, Properties and Applications
Siqueira, G., Bras, J., & Dufresne, A. (2010) · Polymers · doi:10.3390/polym2040728 · Cited by 1,328 · cited 1×
“10,11 Current studies of CNC toxicity have focused on plant fiber-derived CNCs, which are shorter and have smaller cross-sectional dimensions than those derived from animal, bacterial, or algal cellulose.”
Harush-Frenkel, O., Rozentur, E., Benita, S., & Altschuler, Y. (2008) · Biomacromolecules · doi:10.1021/bm700535p · Cited by 405
Villanova, J. C. O., Ayres, E., Carvalho, S. M., Patrício, P. S., Pereira, F. V., & Oréfice, R. L. (2011) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2011.01.005 · Cited by 79
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Current characterization methods for cellulose nanomaterials
Foster, E. J., Moon, R. J., Agarwal, U. P., Bortner, M. J., Bras, J., Camarero-Espinosa, S., Chan, K. J., Clift, M. J. D., Cranston, E. D., Eichhorn, S. J., et al. (2018) · Chemical Society Reviews · doi:10.1039/c6cs00895j · Cited by 1,021
Klemm, D., Cranston, E. D., Fischer, D., Gama, M., Kedzior, S. A., Kralisch, D., Kramer, F., Kondo, T., Lindström, T., Nietzsche, S., et al. (2018) · Materials Today · doi:10.1016/j.mattod.2018.02.001 · Cited by 936
Cao, Y., & Mezzenga, R. (2019) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2019.05.002 · Cited by 649
Kaushik, M., & Moores, A. (2016) · Green Chemistry · doi:10.1039/c5gc02500a · Cited by 606
Biocompatibility of nanomaterials and their immunological properties
Kyriakides, T. R., Raj, A., Tseng, T. H., Xiao, H., Nguyen, R., Mohammed, F. S., Halder, S., Xu, M., Wu, M. J., Bao, S., et al. (2021) · Biomedical Materials · doi:10.1088/1748-605x/abe5fa · Cited by 389
Metadata
- Authors
- Roman, M.
- Venue
- Industrial Biotechnology
- Publisher
- SAGE Publications
- Published
- 2015-02
- Volume
- 11
- Issue
- 1
- Pages
- 25-33
- ISSN
- 1550-9087 (ISSN-L)
- 1931-8421
- OpenAlex
- W1919388396
- Cited by
- 305
- References
- 6
- FWCI
- 8.33
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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