The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment
Open accessAbstract
Acute lung injury (ALI) remains a significant source of morbidity and mortality in the critically ill patient population. Defined by a constellation of clinical criteria (acute onset of bilateral pulmonary infiltrates with hypoxemia without evidence of hydrostatic pulmonary edema), ALI has a high incidence (200,000 per year in the US) and overall mortality remains high. Pathogenesis of ALI is explained by injury to both the vascular endothelium and alveolar epithelium. Recent advances in the understanding of pathophysiology have identified several biologic markers that are associated with worse clinical outcomes. Phase III clinical trials by the NHLBI ARDS Network have resulted in improvement in survival and a reduction in the duration of mechanical ventilation with a lung-protective ventilation strategy and fluid conservative protocol. Potential areas of future treatments include nutritional strategies, statin therapy, and mesenchymal stem cells.
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Cites
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Chen, Y., Wang, L., Kang, Q., Zhang, X., Yu, G., Wan, X., Wang, J., & Zhu, K. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000477308 · Cited by 10,679
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The Acute Respiratory Distress Syndrome
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Self-citationThe Acute Respiratory Distress Syndrome
Ware, L. B., & Matthay, M. A. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005043421806 · Cited by 4,666
Self-citationACUTE RESPIRATORY DISTRESS IN ADULTS
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Incidence and Outcomes of Acute Lung Injury
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Comparison of Two Fluid-Management Strategies in Acute Lung Injury
(2006) · New England Journal of Medicine · doi:10.1056/nejmoa062200 · Cited by 3,538
Thomas, A. C., & Campbell, J. H. (2000) · Cited by 2,800
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Cited by
Role of Nrf2 and Its Activators in Respiratory Diseases
Liu, Q., Gao, Y., & Ci, X. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/7090534 · Cited by 267
Curcumin use in pulmonary diseases: State of the art and future perspectives
Lelli, D., Sahebkar, A., Johnston, T. P., & Pedone, C. (2017) · Pharmacological Research · doi:10.1016/j.phrs.2016.11.017 · Cited by 258
E-cigarette vaping associated acute lung injury (EVALI): state of science and future research needs
Marrocco, A., Singh, D., Christiani, D. C., & Demokritou, P. (2022) · Critical Reviews in Toxicology · doi:10.1080/10408444.2022.2082918 · Cited by 78
“…lungs that disrupts the lung endothelial and epithelial barriers (alveolarcapillary membrane damage), leading to increased permeability, excessive transudation of fluid, recruitment of neutrophils and monocytes in the alveoli, and release of pro-inflammatory cytokines (Johnson and Matthay 2010).”
BackgroundTan, S. C., Bhattamisra, S. K., Chellappan, D. K., & Candasamy, M. (2021) · Applied Sciences · doi:10.3390/app11188475 · Cited by 72
The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice
Park, J.-R., Lee, H., Kim, S.-I., & Yang, S.-R. (2016) · Oncotarget · doi:10.18632/oncotarget.11168 · Cited by 60
Metadata
- Authors
- Johnson, E. R., & Matthay, M. A.
- Venue
- Journal of Aerosol Medicine and Pulmonary Drug Delivery
- Publisher
- SAGE Publications
- Published
- 2010-08
- Volume
- 23
- Issue
- 4
- Pages
- 243-252
- ISSN
- 1941-2703 (ISSN-L)
- 1941-2711
- OpenAlex
- W2008906556
- Cited by
- 783
- References
- 101
- FWCI
- 12.05
- Type
- journal article
- Language
- en
- Open access
- green
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- Johnson, E. R., & Matthay, M. A. (2010). Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment. Journal of Aerosol Medicine and Pulmonary Drug Delivery. https://doi.org/10.1089/jamp.2009.0775
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
