The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Review: Oxidative Stress and Disease
Abstract
This communication briefly reviews aspects of oxidative stress and disease, particularly maturity onset cataract. The review considers a number of issues such as why lens and cataract research is important, what is oxidative stress, its relationship to disease and how does a tissue defend itself against such stress. Three diseases (chronic lung disease, diabetes and Alzheimer's disease) in which oxidative stress has differing roles are briefly discussed. The impact of oxidative stress upon the development of maturity onset cataract is considered and approaches are delineated which will establish the importance of such stress.
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“With aging, a decreased performance of cell endogenous antioxidant system occurs; thus, elderly people are more susceptible to oxidative stress [2, 3].”
From Antioxidants from Plants Protect against Skin Photoaging (2018) · cites this paper as [2]
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Beckman, J. S., Beckman, T. W., Chen, J., Marshall, P. A., & Freeman, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.4.1620 · Cited by 7,029
Role of Oxidative Stress in Development of Complications in Diabetes
Baynes, J. (1991) · Diabetes · doi:10.2337/diab.40.4.405 · Cited by 3,791
Hydrogen peroxide mediates amyloid β protein toxicity
Behl, C. (1994) · Cell · doi:10.1016/0092-8674(94)90131-7 · Cited by 2,074
Oxidative Stress and Diabetic Vascular Complications
Giugliano, D., Ceriello, A., & Paolisso, G. (1996) · Diabetes Care · doi:10.2337/diacare.19.3.257 · Cited by 1,921
Oxidative stress‐induced cataract: mechanism of action
Spector, A. (1995) · The FASEB Journal · doi:10.1096/fasebj.9.12.7672510 · Cited by 896
Self-citationA study of the reactivity of HO2/O2-with unsaturated fatty acids
Bielski, B. H., Arudi, R. L., & Sutherland, M. W. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)32488-8 · Cited by 546
Gardner, P. R., & Fridovich, I. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)50343-x · Cited by 346
National Outcomes of Cataract Extraction
Javitt, J. C., Tielsch, J. M., Canner, J. K., Kolb, M. M., Sommer, A. H., Steinberg, E. P., Steinberg, E. P., Bergner, M., Sommer, A. H., Anderson, G. F., et al. (1992) · Ophthalmology · doi:10.1016/s0161-6420(92)31775-0 · Cited by 302
Free and protein-bound glutathione in normal and cataractous human lenses
Harding, J. J. (1970) · Biochemical Journal · doi:10.1042/bj1170957 · Cited by 290
Nuclear cataract and myopia during hyperbaric oxygen therapy.
Palmquist, B. ‐., Philipson, B., & Barr, P. (1984) · British Journal of Ophthalmology · doi:10.1136/bjo.68.2.113 · Cited by 290
Reaction of No With O2−. Implications for the Action of Endothelium-Derived Relaxing Factor (EDRF)
Sarán, M., Michel, C., Bors, W., & Czapski, G. (1990) · Free Radical Research Communications · doi:10.3109/10715769009149890 · Cited by 269
Glutathione and its function in the lens—An overview
Reddy, V. N. (1990) · Experimental Eye Research · doi:10.1016/0014-4835(90)90127-g · Cited by 245
Lipoprotein glycation and its metabolic consequences
Lyons, T. J., & Jenkins, A. J. (1997) · Current Opinion in Lipidology · doi:10.1097/00041433-199706000-00008 · Cited by 232
Perhydroxyl radical (HOO.) initiated lipid peroxidation. The role of fatty acid hydroperoxides
Aikens, J., & Dix, T. A. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)98591-1 · Cited by 228
Amyloid β-protein toxicity and oxidative stress in Alzheimer's disease
Behl, C. (1997) · Cell and Tissue Research · doi:10.1007/s004410050955 · Cited by 212
Lipoprotein Glycation and Its Metabolic Consequences
Lyons, T. J. (1992) · Diabetes · doi:10.2337/diab.41.2.s67 · Cited by 141
Increased antioxidant enzyme activity in amyloid beta protein-resistant cells
Sagara, Y., Dargusch, R., Klier, F. G., Schubert, D. A., & Behl, C. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00497.1996 · Cited by 127
Spector, A., Yang, Y., Ho, Y., Magnenat, J.-L., Wang, R.-R., Ma, W., & Li, W. (1996) · Experimental Eye Research · doi:10.1006/exer.1996.0063 · Cited by 66
Self-citationDovrat, A., & Gershon, D. (1981) · Experimental Eye Research · doi:10.1016/s0014-4835(81)80105-4 · Cited by 55
Reddy, V. N., Lu, L., Ho, Y., Magnenat, J.-L., Ibaraki, N., Giblin, F. J., & Dang, L. (2010) · Ophthalmologica · doi:10.1159/000310788 · Cited by 54
Activity of glutathione peroxidase and glutathione reductase in the human lens related to age
Rathbun, W. B., & Bovis, M. G. (1986) · Current Eye Research · doi:10.3109/02713688609025177 · Cited by 45
Canner, J. K. (1992) · Archives of Ophthalmology · doi:10.1001/archopht.1992.01080200117038 · Cited by 28
Microperoxidases Catalytically Degrade Reactive Oxygen Species and May Be Anti-Cataract Agents
Spector, A., Ma, W., Wang, R.-R., & Kleiman, N. J. (1997) · Experimental Eye Research · doi:10.1006/exer.1997.0336 · Cited by 24
Self-citationHPLC analysis of lens GSH and GSSG
Chancy, W. G., & Spector, A. (1984) · Current Eye Research · doi:10.3109/02713688408997219 · Cited by 22
Self-citationThe Effect of Catalase Amplification on Immortal Lens Epithelial Cell Lines
Yang, Y., Spector, A., Ma, W., Wang, R.-R., Larsen, K., & Kleiman, N. J. (1998) · Experimental Eye Research · doi:10.1006/exer.1998.0560 · Cited by 18
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Flagged first, then by citations
Research works printed but not linked: 11
- Reddy V.N., 1984, Pittman Publishing Ltd, 65
- Vision Research A, 1999, Exp. Eye Res., 50, 771
- Kupfer C, 1994, Philadelphia, 1249
- Stark W.J., 1989, Ophthalmol., 107, 1441
- Kupfer C, 1984, Trans. Ophthalmol Soc., 104, 1
- Klausner R.D., 1998, Inc., 99
- Stryer L., 1988, New York, 595
- Sies H., 1985, London, 1
- Khu P.M., 1994, Philadelphia, 591
- Jaffe N.S., 1992, New York, 8
- Jaffe N.S., 1992, New York, 7
Cited by
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Dandona, P., Aljada, A., Mohanty, P., Ghanim, H., Hamouda, W., Assian, E., & Ahmad, S. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.7.7623 · Cited by 698
Curcumin and Turmeric Delay Streptozotocin-Induced Diabetic Cataract in Rats
Suryanarayana, P., Saraswat, M., Mrudula, T., Krishna, T. P., Krishnaswamy, K., & Reddy, G. B. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.04-1304 · Cited by 308
Antioxidants from Plants Protect against Skin Photoaging
Petruk, G., Del Giudice, R., Rigano, M. M., & Monti, D. M. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/1454936 · Cited by 283
Oxidative Stress, Lens Gap Junctions, and Cataracts
Berthoud, V. M., & Beyer, E. C. (2008) · Antioxidants and Redox Signaling · doi:10.1089/ars.2008.2119 · Cited by 259
Role of curcumin in health and disease
Pari, L., Tewas, D., & Eckel, J. (2008) · Archives of Physiology and Biochemistry · doi:10.1080/13813450802033958 · Cited by 248
Metadata
- Authors
- SPECTOR, A.
- Affiliations
- Columbia University Irving Medical Center (US)
- Corresponding author
- SPECTOR, ABRAHAM
- Venue
- Journal of Ocular Pharmacology and Therapeutics
- Publisher
- SAGE Publications
- Published
- 2000-04
- Volume
- 16
- Issue
- 2
- Pages
- 193-201
- ISSN
- 1080-7683 (ISSN-L)
- 1557-7732
- OpenAlex
- W2090028564
- Cited by
- 244
- References
- 25
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 11 · 2023: 10 · 2022: 7 · 2021: 8 · 2020: 12 · 2019: 7 · 2018: 10 · 2017: 11 · 2016: 6 · 2015: 8 · 2014: 14 · 2013: 12 · 2012: 13
- FWCI
- 3.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Ocular Pharmacology and Therapeutics (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Eye Institute
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Antioxidant Activity and Oxidative Stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connexins and lens biology
- Keywords
- oxidative stress, lens, cataract, chronic lung disease, diabetes mellitus, Alzheimer's disease, antioxidant defense, pathogenesis
- MeSH terms
- Animals, Cataract, Humans, Lens, Crystalline, Reactive Oxygen Species, Oxidative Stress
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