The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Association Between Maternal Mood and Oxytocin Response to Breastfeeding
Open accessAbstract
BACKGROUND: Postpartum depression is associated with reduced breastfeeding duration. We previously hypothesized that shared neuroendocrine mechanisms underlie this association. We sought to measure the association between maternal mood and neuroendocrine response to breastfeeding. METHODS: We conducted a longitudinal cohort study of women recruited during pregnancy who intended to breastfeed. Baseline depression and anxiety history were assessed with a structured clinical interview. We measured mood symptoms using validated psychometric instruments, and we quantified affect and neuroendocrine responses to breastfeeding during laboratory visits at 2 and 8 weeks postpartum. RESULTS: We recruited 52 women who intended to breastfeed, among whom 47 completed 8-week follow-up. Duration and intensity of breastfeeding through 8 weeks were similar among mothers with lower versus higher anxiety and depression scores. In the third trimester, oxytocin was inversely correlated with Edinburgh Postnatal Depression Scale (EPDS) score (p=0.03). We did not find differences in neuroendocrine profile during breastfeeding at 2 weeks postpartum. Among the 39 women who breastfed at 8 weeks postpartum, oxytocin area under the curve during breastfeeding was inversely correlated with maternal EPDS and STAI-State and STAI-Trait anxiety scores (all p≤0.01). Higher anxiety and depression scores was further associated with lower oxytocin (group p<0.05) during feeding. During feeding at both visits, higher anxiety and depression scores were also associated with more negative affect: mothers reported feeling less happy and more depressed, overwhelmed, and stressed during feeding than women with lower scores. CONCLUSION: Symptoms of depression and anxiety were associated with differences in oxytocin response and affect during breastfeeding.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Mothers with depressive symptoms were significantly more likely to discontinue breastfeeding (early interruption of exclusive breastfeeding in the first months),41,59,69,71,90,91,118,119,137”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [41]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Maternal depressive symptoms appeared to be correlated with lower oxytocin,41 total T441 concentrations, and higher TGF-β2 concentrations.77”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [41]
The cited source says what the claim attributes to it.
In the citing paper
“Maternal depressive symptoms appeared to be correlated with lower oxytocin,41 total T441 concentrations, and higher TGF-β2 concentrations.77”
From Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes (2019) · cites this paper as [41]
The cited source says what the claim attributes to it.
In the citing paper
“Several studies found that mothers who report more anxiety and depression also demonstrate lower levels of oxytocin when breastfeeding than asymptomatic breastfeeding mothers (Stuebe et al., 2013; Cox et al., 2015; Pawluski et al., 2017).”
From The evolved nest, oxytocin functioning, and prosocial development (2023) · cites this paper as Stuebe et al., 2013
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
(1970) · Cited by 24,983
Detection of Postnatal Depression: Development of the 10-item Edinburgh Postnatal Depression Scale
Cox, J. L., Holden, J. M., & Sagovsky, R. (1987) · British Journal of Psychiatry · doi:10.1192/bjp.150.6.782 · Cited by 14,183
Pruessner, J. C., Kirschbaum, C., Meinlschmid, G., & Hellhammer, D. H. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(02)00108-7 · Cited by 3,638
State-Trait Anxiety Inventory for Adults
Spielberger, C. D. (2012) · PsycTESTS Dataset · doi:10.1037/t06496-000 · Cited by 3,479
Breastfeeding and Maternal and Infant Health Outcomes In Developed Countries
(2007) · AAP Grand Rounds · doi:10.1542/gr.18-2-15 · Cited by 1,556
Breastfeeding and maternal and infant health outcomes in developed countries.
Ip, S., Chung, M. C., Raman, G., Chew, P., Magula, N. P., DeVine, D., Trikalinos, T. A., & Lau, J. (2007) · PubMed Central · Cited by 1,416
Gaynes, B. N., Gavin, N., Meltzer-Brody, S., Lohr, K. N., Swinson, T., Gartlehner, G., Brody, S., & Miller, W. C. (2005) · PsycEXTRA Dataset · doi:10.1037/e439372005-001 · Cited by 1,211
Self-citationRaison, C. L., & Miller, A. H. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.9.1554 · Cited by 1,197
The Breastfeeding Self‐Efficacy Scale: Psychometric Assessment of the Short Form
Dennis, C. (2003) · Journal of Obstetric, Gynecologic & Neonatal Nursing · doi:10.1177/0884217503258459 · Cited by 919
Dennis, C.-L., & McQueen, K. (2009) · Pediatrics · doi:10.1542/peds.2008-1629 · Cited by 533
Flagged first, then by citations
Research works printed but not linked: 7
- Ip S, 2007, Evid Rep Technol Assess, 153, 1
- Stuebe A, 2009, Rev Obstet Gynecol, 2, 222
- Gaynes BN, 2005, Evid Rep Technol Assess (Summ), 119, 1
- 17. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured clinical interview for DSM-IV-TR Axis I disorders, research version, non-patient edition (SCID-I/NP). New York: Biometrics Research, New York State Psychiatric Institute, 2002.
- 10.1192/bjp.150.6.782 · DOI · Paper page
- Grewen KM, 2010, Psychophysiol, 47, 625
- 10.1210/jc.81.5.1912 · DOI
Cited by
Sorted by citations
Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes
Slomian, J., Honvo, G., Emonts, P., Reginster, J.-Y., & Bruyère, O. (2019) · Women's Health · doi:10.1177/1745506519844044 · Cited by 1,496
Yim, I. S., Tanner Stapleton, L. R., Guardino, C. M., Hahn-Holbrook, J., & Dunkel Schetter, C. (2015) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-101414-020426 · Cited by 749
Oxytocin pathways and the evolution of human behavior
Carter, C. S. (2014) · Annual Review of Psychology · doi:10.1146/annurev-psych-010213-115110 · Cited by 714
Postpartum depression: Etiology, treatment and consequences for maternal care
Brummelte, S., & Galea, L. A. M. (2016) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.08.008 · Cited by 567
Pathophysiological mechanisms implicated in postpartum depression
Payne, J. L., & Maguire, J. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.12.001 · Cited by 459
Metadata
- Authors
- Stuebe, A. M., Grewen, K., & Meltzer-Brody, S.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Stuebe, Alison M.
- Venue
- Journal of Women's Health
- Publisher
- SAGE Publications
- Published
- 2013-04
- Volume
- 22
- Issue
- 4
- Pages
- 352-361
- ISSN
- 1059-7115 (ISSN-L)
- 1540-9996
- 1931-843X
- PMC
- PMC3627433
- OpenAlex
- W2008023822
- Cited by
- 295
- References
- 43
- Citations by year
- 2026: 9 · 2025: 15 · 2024: 19 · 2023: 18 · 2022: 35 · 2021: 39 · 2020: 42 · 2019: 27 · 2018: 16 · 2017: 24 · 2016: 15 · 2015: 27 · 2014: 4 · 2013: 5
- FWCI
- 17.34
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Journal of Women s Health (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5k01da019949-02, K01DA019949-01A1)
- National Institute of Mental Health (K23MH085165)
- National Institute on Drug Abuse (P01DA022446, K01DA019949-01A1)
- National Center for Research Resources (UL1RR025747)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (K12HD050113)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Epidemiology › Breastfeeding Practices and Influences
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Keywords
- postpartum depression, maternal anxiety, breastfeeding, oxytocin, neuroendocrine response, maternal mood, negative affect, breastfeeding duration, Edinburgh Postnatal Depression Scale, state-trait anxiety
- MeSH terms
- Adult, Affect, Anxiety, Breast Feeding, Depression, Female, Humans, Oxytocin, Pregnancy, Pregnancy Trimester, Third, Prospective Studies, Postpartum Period
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
