The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Prognostic Value of The Glasgow Coma Scale And Pupil Reactivity in Traumatic Brain Injury Assessed Pre-Hospital And on Enrollment: An IMPACT Analysis
Abstract
We studied the prognostic strength of the individual components of the Glasgow Coma Scale (GCS) and pupil reactivity to Glasgow Outcome Score (GOS) at 6 months post-injury. A total of 8721 moderate or severe traumatic brain injury (TBI) patient data from the IMPACT database on traumatic brain injury comprised the study cohort. The associations between motor score and pupil reactivity and 6-month GOS were analyzed by binary logistic regression and proportional odds methodology. The strength of prognostic effects were expressed as the unadjusted odds ratios presented for all individual studies as well as in meta-analysis. We found a consistent strong association between motor score and 6-month GOS across all studies (OR 1.74-7.48). The Eye and Verbal components were also strongly associated with GOS. In the pooled population, one or both un-reactive pupils and lower motor scores were significantly associated with unfavorable outcome (range 2.71-7.31). We also found a significant change in motor score from pre-hospital direct to study hospital enrollment ( p < 0.0001) and from the first in-hospital to study enrollment scores (p < 0.0001). Pupil reactivity was more robust between these time points. It is recommended that the study hospital enrollment GCS and pupil reactivity be used for prognostic analysis.
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Cites
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THE ROLE OF SECONDARY BRAIN INJURY IN DETERMINING OUTCOME FROM SEVERE HEAD INJURY
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Self-citationAssessment and prognosis of coma after head injury
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Self-citationPrognosis of Patients with Severe Head Injury
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Prognosis and Clinical Trial Design in Traumatic Brain Injury: The IMPACT Study
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Self-citationHukkelhoven, C. W. P. M., Steyerberg, E. W., Habbema, J. D. F., Farace, E., Marmarou, A., Murray, G. D., Marshall, L. F., & Maas, A. I. R. (2005) · Journal of Neurotrauma · doi:10.1089/neu.2005.22.1025 · Cited by 301
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Cited by
Multivariable Prognostic Analysis in Traumatic Brain Injury: Results from The IMPACT Study
Murray, G. D., Butcher, I., McHugh, G. S., Lu, J., Mushkudiani, N. A., Maas, A. I. R., Marmarou, A., & Steyerberg, E. W. (2007) · Journal of Neurotrauma · doi:10.1089/neu.2006.0035 · Cited by 631
Self-citationEarly prognosis in traumatic brain injury: from prophecies to predictions
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Self-citationSevere traumatic brain injury: targeted management in the intensive care unit
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Prognosis and Clinical Trial Design in Traumatic Brain Injury: The IMPACT Study
Maas, A. I. R., Marmarou, A., Murray, G. D., Teasdale, S. G. M., & Steyerberg, E. W. (2007) · Journal of Neurotrauma · doi:10.1089/neu.2006.0024 · Cited by 355
Self-citationWinn, M. B., Wendt, D., Koelewijn, T., & Kuchinsky, S. E. (2018) · Trends in Hearing · doi:10.1177/2331216518800869 · Cited by 339
Metadata
- Authors
- Marmarou, A., Lu, J., Butcher, I., McHugh, G. S., Murray, G. D., Steyerberg, E. W., Mushkudiani, N. A., Choi, S., & Maas, A. I. R.
- Venue
- Journal of Neurotrauma
- Publisher
- SAGE Publications
- Published
- 2007-02
- Volume
- 24
- Issue
- 2
- Pages
- 270-280
- ISSN
- 0897-7151 (ISSN-L)
- 1557-9042
- OpenAlex
- W1968288411
- Cited by
- 358
- References
- 28
- FWCI
- 8.40
- Type
- journal article
- Language
- en
- Open access
- closed
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- Marmarou, A., Lu, J., Butcher, I., McHugh, G. S., Murray, G. D., Steyerberg, E. W., Mushkudiani, N. A., Choi, S., & Maas, A. I. R. (2007). Prognostic Value of The Glasgow Coma Scale And Pupil Reactivity in Traumatic Brain Injury Assessed Pre-Hospital And on Enrollment: An IMPACT Analysis. Journal of Neurotrauma. https://doi.org/10.1089/neu.2006.0029
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
