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Cited by 514

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Symptomatology and Functional Outcome in Mild Traumatic Brain Injury: Results from the Prospective TRACK-TBI Study

Open access
McMahon, Paul J., Hricik, Allison, Yue, John K., Puccio, Ava M., Inoue, Tomoo, Lingsma, Hester F., Beers, Sue R., Gordon, Wayne A., Valadka, Alex B., Manley, Geoffrey T., Okonkwo and the TRACK-TBI investiga, David O., Casey, Scott S., Cooper, Shelly R., Dams-O'Connor, Kristen, Menon, David K., Sorani, Marco D., Yuh, Esther L., Mukherjee, Pratik, Schnyer, David M., Vassar, Mary J.·2014·Journal of Neurotrauma
DOI 10.1089/neu.2013.2984
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Abstract

Mild Traumatic Brain Injury (mTBI), or concussion, is a major public health concern. There is controversy in the literature regarding the true incidence of postconcussion syndrome (PCS), with the constellation of physical, cognitive, emotional, and sleep symptoms after mTBI. In the current study, we report on the incidence and evolution of PCS symptoms and patient outcomes after mTBI at 3, 6, and 12 months in a large, prospective cohort of mTBI patients. Participants were identified as part of the prospective, multi-center Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study. The study population was mTBI patients (Glasgow Coma Scale score of 13-15) presenting to the emergency department, including patients with a negative head computed tomography discharged to home without admission to hospital; 375 mTBI subjects were included in the analysis. At both 6 and 12 months after mTBI, 82% (n=250 of 305 and n=163 of 199, respectively) of patients reported at least one PCS symptom. Further, 44.5 and 40.3% of patients had significantly reduced Satisfaction With Life scores at 6 and 12 months, respectively. At 3 months after injury, 33% of the mTBI subjects were functionally impaired (Glasgow Outcome Scale-Extended score ≤6); 22.4% of the mTBI subjects available for follow-up were still below full functional status at 1 year after injury. The term "mild" continues to be a misnomer for this patient population and underscores the critical need for evolving classification strategies for TBI for targeted therapy.

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Metadata

Authors
McMahon, P. J., Hricik, A., Yue, J. K., Puccio, A. M., Inoue, T., Lingsma, H. F., Beers, S. R., Gordon, W. A., Valadka, A. B., Manley, G. T., Okonkwo and the TRACK-TBI investiga, D. O., Casey, S. S., Cooper, S. R., Dams-O'Connor, K., Menon, D. K., Sorani, M. D., Yuh, E. L., Mukherjee, P., Schnyer, D. M., & Vassar, M. J.
Venue
Journal of Neurotrauma
Publisher
SAGE Publications
Published
2014-01
Volume
31
Issue
1
Pages
26-33
ISSN
  • 0897-7151 (ISSN-L)
  • 1557-9042
DOI
10.1089/neu.2013.2984
OpenAlex
W2090020945
Cited by
514
References
6
FWCI
16.21
Type
journal article
Language
en
Open access
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