A new 675 nm laser device in the treatment of facial aging: A prospective observational study
Abstract
Objective: To evaluate the effectiveness and safety of a 675 nm laser device in the treatment of facial aging. Background: Wrinkles represent a major sign of aging skin and are considered a major topic in cosmetic dermatology, representing a common problem that negatively impacts patients' quality of life. Different types of treatments are currently available. The aim of this study was to assess the efficacy and safety of a new 675 nm laser source system on facial wrinkles. Methods: A total of 22 consecutive female (age 49.36 ± 8.72) patients, with Fitzpatrick skin types II–IV and facial wrinkles, were treated with three sessions of a 675 nm laser system. Efficacy of treatment was assessed using the Modified Fitzpatrick Wrinkles Scale pre and postoperatively before 3 months. Results: All 22 patients treated with the 675 nm laser had a significant improvement of facial wrinkles according to the FWS (from 1.59 ± 0.80 to 1 ± 0.64; p ≤ 0.001). No side effects occurred except a mild erythematous rash in two patients. Conclusions: This novel 675 nm laser system can be considered a promising and effective tool in patients with facial wrinkles, and it involves a simple post-treatment management.
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Histological and ultrastructural studies show epidermal hyperplasia, damage and disorder of collagen fibers, and accumulation of abnormal elastic substances in connective tissue in photoaged skin.
“Histological and ultrastructural studies have shown epidermal hyperplasia, damage, and disorder of collagen fibers, and a large accumulation of abnormal elastic substances in connective tissue in photoaged skin [32,33].”
From Boosting the Photoaged Skin: The Potential Role of Dietary Components (2021) · cites this paper as [32]
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- Authors
- Cannarozzo, G., Fazia, G., Bennardo, L., Tamburi, F., Amoruso, G. F., Del Duca, E., & Nisticò, S. P.
- Affiliations
- University of Rome Tor Vergata (IT)
- Magna Graecia University (IT)
- Azienda Ospedaliera di Cosenza (IT)
- Department of Dermatology, Magna Graecia University, Catanzaro, Italy.
- Corresponding author
- Bennardo, Luigi
- Venue
- Photobiomodulation Photomedicine and Laser Surgery
- Publisher
- SAGE Publications
- Published
- 2021-02-01
- Volume
- 39
- Issue
- 2
- Pages
- 118-122
- ISSN
- 2578-5478 (ISSN-L)
- OpenAlex
- W3122719396
- Cited by
- 48
- References
- 15
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 7 · 2023: 10 · 2022: 8 · 2021: 10
- FWCI
- 7.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Photobiomodulation Photomedicine and Laser Surgery (publishedVersion)
- PubMed (publishedVersion)
- IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
- Health Sciences › Medicine › Dermatology › Facial Rejuvenation and Surgery Techniques
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Keywords
- facial wrinkles, facial aging, skin rejuvenation, treatment efficacy, treatment safety, erythema, Fitzpatrick skin type
- MeSH terms
- Adult, Aging, Female, Humans, Middle Aged, Quality of Life, Skin Aging, Treatment Outcome, Lasers, Solid-State
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