The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approaches

Das, Ruud, Jahr, Holger, van Osch, Gerjo J.V.M., Farrell, Eric·2010·Tissue Engineering Part B Reviews

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Items 101–200 of 297

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  2. Hypoxia and Trophoblast Differentiation: A Key Role for PPARγ
    Véronique Taché, Aleksandar Ciric, Matteo Moretto-Zita, Yingchun Li, Julia Peng, Emin Maltepe, David S. Milstone, Mana M. Parast · 2013 · Stem Cells and Development
  3. Stromal cell-derived factor-1-directed bone marrow mesenchymal stem cell migration in response to inflammatory and/or hypoxic stimuli
    Yang Yu, Rui‐Xin Wu, Li‐Na Gao, Yu Xia, Hao‐Ning Tang, Fa‐Ming Chen · 2016 · Cell Adhesion & Migration
  4. Process engineering of stem cell metabolism for large scale expansion and differentiation in bioreactors
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  5. Hypoxia Preconditioning of Human MSCs: a Direct Evidence of HIF-1α and Collagen Type XV Correlation
    Elisabetta Lambertini, Letizia Penolazzi, Marco Angelozzi, Letícia Scussel Bergamin, Cristina Manferdini, Francesco Vieceli Dalla Sega, Francesca Paolella, Gina Lisignoli, Roberta Piva · 2018 · Cellular Physiology and Biochemistry
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  7. Strategies to Enhance Mesenchymal Stem Cell-Based Therapies for Acute Respiratory Distress Syndrome
    Jibin Han, Yanmin Li, Yuanyuan Li · 2019 · Stem Cells International
  8. Hypoxic preconditioning increases the protective effect of bone marrow mesenchymal stem cells on spinal cord ischemia/reperfusion injury
    ZHILIN WANG, Bo Fang, Zhibin Tan, Dong Zhang, Hong Ma · 2016 · Molecular Medicine Reports
  9. Trimetazidine Protects Umbilical Cord Mesenchymal Stem Cells Against Hypoxia and Serum Deprivation Induced Apoptosis by Activation of Akt
    Xuhe Gong, Guangpu Fan, Wei Wang, Guogan Wang · 2014 · Cellular Physiology and Biochemistry
  10. The Role of Environmental Factors in Regulating the Development of Cartilaginous Grafts Engineered Using Osteoarthritic Human Infrapatellar Fat Pad–Derived Stem Cells
    Yurong Liu, Conor Timothy Buckley, Richard Downey, Kevin James Mulhall, Daniel John Kelly · 2012 · Tissue Engineering Part A
  11. Encapsulation of Mesenchymal Stem Cells Improves Vascularization of Alginate-Based Scaffolds
    Dominik Steiner, Lara F. Lingens, Laura Elisabeth Fischer, Katrin Köhn, Rainer Detsch, Aldo Roberto Boccaccini, Tobias Fey, Peter Greil, Christian Weis, Justus P. Beier et al. · 2018 · Tissue Engineering Part A
  12. Lysophosphatidic Acid Protects Human Mesenchymal Stromal Cells from Differentiation-Dependent Vulnerability to Apoptosis
    Bernard Y.K. Binder, Damian C. Genetos, Jonathan Kent Leach · 2013 · Tissue Engineering Part A
  13. Comparison of the depolarization response of human mesenchymal stem cells from different donors
    Sarah Sundelacruz, Michael G. Levin, David Lee Kaplan · 2015 · Scientific Reports
  14. Endothelial differentiation of bone marrow mesenchyme stem cells applicable to hypoxia and increased migration through Akt and NFκB signals
    Cheng Liu, An-Ly Tsai, Ping-Chia Li, Chia-Wei Huang, Chia‐Ching Wu · 2017 · Stem Cell Research & Therapy
  15. The effect of hypoxia on myogenic differentiation and multipotency of the skeletal muscle-derived stem cells in mice
    Mohamed I. Elashry, Mebrie Zemene Kinde, Michele Christian Klymiuk, Asmaa Eldaey, Sabine Wenisch, Stefan Arnhold · 2022 · Stem Cell Research & Therapy
  16. Hypoxia Created Human Mesenchymal Stem Cell Sheet for Prevascularized 3D Tissue Construction
    Lijun Zhang, Qi Xing, Zichen Qian, Mitchell Tahtinen, Zhaoqiang Zhang, Emily R. Shearier, Shaohai Qi, Feng Zhao · 2015 · Advanced Healthcare Materials
  17. Physoxia alters human mesenchymal stem cell secretome
    Marwan M. Merkhan, Matthew T. Shephard, Nicholas Robert Forsyth · 2021 · Journal of Tissue Engineering
  18. LncRNA DNM3OS regulates GREM2 via miR-127-5p to suppress early chondrogenic differentiation of rat mesenchymal stem cells under hypoxic conditions
    Xiaozhong Zhou, Wangyang Xu, Yeyang Wang, Hui Zhang, Li Zhang, Chao Li, Shun Yao, Zixiang Huang, Lishan Huang, Dixin Luo · 2021 · Cellular & Molecular Biology Letters
  19. Effects of Hypoxia and Chitosan on Equine Umbilical Cord‐Derived Mesenchymal Stem Cells
    Dominique J. Griffon, J. Cho, John R. Wagner, Chandrashekhar Charavaryamath, Jianshu Wei, Amy J. Wagoner Johnson · 2016 · Stem Cells International
  20. Passage‐dependent cancerous transformation of human mesenchymal stem cells under carcinogenic hypoxia
    Spencer W. Crowder, Linda W. Horton, Sue Hyun Lee, Colt M. McClain, Oriana E. Hawkins, Amanda M. Palmer, Hojae Bae, Ann J. Richmond, Hak‐Joon Sung · 2013 · The FASEB Journal
  21. Hypoxic conditioned medium of placenta-derived mesenchymal stem cells protects against scar formation
    Lili Du, Runxiao Lv, Xiaoyi Yang, Shaohang Cheng, Tingxian Ma, Jing Xu · 2016 · Life Sciences
  22. SDF-1α/CXCR4 Axis Mediates The Migration of Mesenchymal Stem Cells to The Hypoxic-Ischemic Brain Lesion in A Rat Model.
    Qin Yu, Lizhen Liu, Jie Lin, Yan Wang, Xiaobo Xuan, Ying Guo, Shaojun Hu · 2015 · Europe PMC (PubMed Central)
  23. Cobalt Chloride Enhances the Anti-Inflammatory Potency of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells through the ERK-HIF-1α-MicroRNA-146a-Mediated Signaling Pathway
    Ji‐Hye Kwak, Soo Jin Choi, Wonil Oh, Yoon Sun Yang, Hong Bae Jeon, Eun Su Jeon · 2018 · Stem Cells International
  24. Osteogenic differentiation and osteochondral tissue engineering using human adipose‐derived stem cells
    Nastaran Mahmoudifar, Pauline M. Doran · 2012 · Biotechnology Progress
  25. The Role of Extracellular Vesicles in Optic Nerve Injury: Neuroprotection and Mitochondrial Homeostasis
    Mira Park, Hyun Ah Shin, Van‐An Duong, Hookeun Lee, Helen Lew · 2022 · Cells
  26. Pyrvinium, a potent small molecule Wnt inhibitor, increases engraftment and inhibits lineage commitment of mesenchymal stem cells ( MSCs )
    Sarika Saraswati, Desirae L. Deskins, Ginger E. Holt, Pampee Paul Young · 2012 · Wound Repair and Regeneration
  27. Serum-Free Culture of Human Mesenchymal Stem Cell Aggregates in Suspension Bioreactors for Tissue Engineering Applications
    Leah Allen, John Robert Matyas, Mark Ungrin, David A. Hart, Arindom Sen · 2019 · Stem Cells International
  28. Early Growth Response Genes Signaling Supports Strong Paracrine Capability of Mesenchymal Stem Cells
    Kenichi Tamama, Dominique J. Barbeau · 2012 · Stem Cells International
  29. Effect of 17β-estradiol on mediators involved in mesenchymal stromal cell trafficking in cell therapy of diabetes
    Solmaz Mirzamohammadi, Ehsan Aali, Rezvan Najafi, Tunku Kamarul, Mehrnaz Mehrabani, Azadeh Aminzadeh, Ali Mohammad Sharifi · 2014 · Cytotherapy
  30. Mesenchymal stem cell-based developmental endothelial locus-1 gene therapy for acute lung injury induced by lipopolysaccharide in mice
    Yunfeng Zhao, Wei Xiong, XUE-LING WU · 2014 · Molecular Medicine Reports
  31. Cell survival and redistribution after transplantation into damaged myocardium
    Hao Zhang, Haibo Chen, Wei Wang, Yingjie Wei, Shengshou Hu · 2010 · Journal of Cellular and Molecular Medicine
  32. Rapid and efficient generation of neural progenitors from adult bone marrow stromal cells by hypoxic preconditioning
    Kwan Long Mung, Yat-Ping Tsui, Evelyn Wing‐Yin Tai, YS Chan, Daisy Kwok‐Yan Shum, Graham Ka‐Hon Shea · 2016 · Stem Cell Research & Therapy
  33. Determination of optimized oxygen partial pressure to maximize the liver regenerative potential of the secretome obtained from adipose-derived stem cells
    Sang Chul Lee, Kee‐Hwan Kim, Ok‐Hee Kim, Sang Kuon Lee, Ha‐Eun Hong, Seong Su Won, Sang‐Jin Jeon, Byung Jo Choi, Wonjun Jeong, Say‐June Kim · 2017 · Stem Cell Research & Therapy
  34. Repopulation of decellularised articular cartilage by laser-based matrix engraving
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  35. The Role of Dissolved Oxygen Levels on Human Mesenchymal Stem Cell Culture Success, Regulatory Compliance, and Therapeutic Potential
    Soukaina Bahsoun, Karen Coopman, Nicholas Robert Forsyth, Elizabeth C. Akam · 2018 · Stem Cells and Development
  36. Novel preconditioning strategies for enhancing the migratory ability of mesenchymal stem cells in acute kidney injury
    Lingfei Zhao, Chenxia Hu, Ping Zhang, Hua Jiang, Jianghua Chen · 2018 · Stem Cell Research & Therapy
  37. Bioreactor-Controlled Physoxia Regulates TGF-β Signaling to Alter Extracellular Matrix Synthesis by Human Chondrocytes
    Holger Jahr, Seval Gunes, Annika-Ricarda Kuhn, Sven Nebelung, Thomas Pufe · 2019 · International Journal of Molecular Sciences
  38. A comparative analysis of human mesenchymal stem cell response to hypoxia in vitro: Implications to translational strategies
    Beatrice Dionigi, Azra Ahmed, Elliot C. Pennington, David Zurakowski, Dario O. Fauza · 2014 · Journal of Pediatric Surgery
  39. The effect of clinically relevant doses of immunosuppressive drugs on human mesenchymal stem cells
    Eliška Javorková, Julie Vackova, Michaela Hájková, Barbora Heřmánková, Alena Zajı́cová, Vladimı́r Holáň, Magdaléna Krulová · 2017 · Biomedicine & Pharmacotherapy
  40. Pre-Treatment of Human Mesenchymal Stem Cells With Inflammatory Factors or Hypoxia Does Not Influence Migration to Osteoarthritic Cartilage and Synovium
    Maarten J. C. Leijs, Gerben M. van Buul, Jan A.N. Verhaar, Martin Johannes Hoogduijn, P.K. Bos, Gerjo J.V.M. van Osch · 2017 · The American Journal of Sports Medicine
  41. Differentiation Potential of Early- and Late-Passage Adipose-Derived Mesenchymal Stem Cells Cultured under Hypoxia and Normoxia
    Ashley G. Zhao, Kiran Shah, Julien Freitag, Brett A. Cromer, Hüseyin Sümer · 2020 · Stem Cells International
  42. Incremental benefits of repeated mesenchymal stromal cell administration compared with solitary intervention after myocardial infarction
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  43. Endothelial progenitor cell recruitment in a microfluidic vascular model
    Daniel M. Lewis, Hasan Erbil Abaci, Yu Xu, Sharon Gerecht · 2015 · Biofabrication
  44. Tetra-sulfonate phthalocyanine zinc-bovine serum albumin conjugate-mediated photodynamic therapy of human glioma
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  45. Hypoxia‐induced increase in Sug1 leads to poor post‐transplantation survival of allogeneic mesenchymal stem cells
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  46. Classification and Characteristics of Mesenchymal Stem Cells and Its Potential Therapeutic Mechanisms and Applications against Ischemic Stroke
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  49. Hypoxia Enhances Protective Effect of Placental-Derived Mesenchymal Stem Cells on Damaged Intestinal Epithelial Cells by Promoting Secretion of Insulin-Like Growth Factor-1
    Lili Du, Yanqiu Yu, Haiying Ma, Xiaomei Lu, Ling Ma, Yunan Jin, Haipeng Zhang · 2014 · International Journal of Molecular Sciences
  50. Cell-bricks based injectable niche guided persistent ectopic chondrogenesis of bone marrow-derived mesenchymal stem cells and enabled nasal augmentation
    Ruikai Ba, Jianhua Wei, Man Li, Xiaobing Cheng, Yimin Zhao, Wei Te Wu · 2015 · Stem Cell Research & Therapy
  51. Human Limbal Mesenchymal Stem Cells Express ABCB5 and Can Grow on Amniotic Membrane
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  52. Advances in the Treatment of Ischemic Diseases by Mesenchymal Stem Cells
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  53. Effect of Hypoxia Preconditioned Adipose-Derived Mesenchymal Stem Cell Conditioned Medium on Cerulein-Induced Acute Pancreatitis in Mice
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  54. The mitochondrial-derived peptide MOTS-c promotes homeostasis in aged human placenta-derived mesenchymal stem cells in vitro
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  55. Identification and characterization of stem cell secretome-based recombinant proteins for wound healing applications
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  56. Mesenchymal Stem Cells Respond to Hypoxia by Increasing Diacylglycerols
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  57. Investigation of modified platelet-rich plasma (mPRP) in promoting the proliferation and differentiation of dental pulp stem cells from deciduous teeth
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  58. Exosomes derived from hypoxic mesenchymal stem cells restore ovarian function by enhancing angiogenesis
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  59. Development of a process control strategy for the serum-free microcarrier expansion of human mesenchymal stem cells towards cost-effective and commercially viable manufacturing
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  60. Impact of oxygen concentration on growth of mesenchymal stromal cells from the marrow of patients with chronic lymphocytic leukemia
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  61. A microfluidic oxygen sink to create a targeted cellular hypoxic microenvironment under ambient atmospheric conditions
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  62. Influence of caspase-3 silencing on the proliferation and apoptosis of rat bone marrow mesenchymal stem cells under hypoxia.
    Ping Hua, Jialiang Liu, Jun Tao, Jianyang Liu, Songran Yang · 2015 · PubMed Central
  63. Challenges and research progress of the use of mesenchymal stem cells in the treatment of ischemic stroke
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  64. Tripeptide-based macroporous hydrogel improves the osteogenic microenvironment of stem cells
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  65. Adipose tissue and bone marrow-derived stem cells react similarly in an ischaemia-like microenvironment
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  66. Corticosterone Mediates the Inhibitory Effect of Restraint Stress on the Migration of Mesenchymal Stem Cell to Carbon Tetrachloride-Induced Fibrotic Liver by Downregulating CXCR4/7 Expression
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  67. Changes in expression of cartilaginous genes during chondrogenesis of Wharton’s jelly mesenchymal stem cells on three-dimensional biodegradable poly(L-lactide-co-glycolide) scaffolds
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  68. Ceramic devices for bone regeneration
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  69. CXCR4 Antagonist AMD3100 Promotes Mesenchymal Stem Cell Mobilization in Rats Preconditioned with the Hypoxia-Mimicking Agent Cobalt Chloride
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  70. Exosomes Derived from Bone Marrow-Mesenchymal Stem Cells Attenuates Cisplatin-Induced Ototoxicity in a Mouse Model
    Tao Yang, Wei Li, Anquan Peng, Jia Liu, Qin Wang · 2022 · Journal of Clinical Medicine
  71. Physiologic isolation and expansion of human mesenchymal stem/stromal cells for manufacturing of cell‐based therapy products
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  72. Mesenchymal stem cells enchanced by salidroside to inhibit ferroptosis and improve premature ovarian insufficiency via Keap1/Nrf2/GPX4 signaling
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  73. The role of oxygen tension in cell fate and regenerative medicine: implications of hypoxia/hyperoxia and free radicals
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  74. Hypoxia Preconditioning of Tissue-Engineered Mucosa Enhances Its Angiogenic Capacity In Vitro
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  75. A Monte Carlo framework for managing biological variability in manufacture of autologous cell therapy from mesenchymal stromal cells therapies
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  77. A Computational Tool for the Upscaling of Regular Scaffolds During In Vitro Perfusion Culture
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  78. Females transplanted with ovaries subjected to hypoxic preconditioning show impair of ovarian function
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  79. Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects
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  80. Osteoarthritic Milieu Affects Adipose‐Derived Mesenchymal Stromal Cells
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  88. The balance between proliferation and transcription of angiogenic factors of mesenchymal stem cells in hypoxia
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  89. Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells
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  90. Osteogenic Differentiation of Adipose-Derived Stem Cells Is Hypoxia-Inducible Factor-1 Independent
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  92. Hypoxic Incubation Conditions for Optimized Manufacture of Tenocyte-Based Active Pharmaceutical Ingredients of Homologous Standardized Transplant Products in Tendon Regenerative Medicine
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  94. Time course effect of hypoxia on bone marrow-derived endothelial progenitor cells and their effects on left ventricular function after transplanted into acute myocardial ischemia rat.
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  95. Hyperthermia-Conditioned OECs Serum-Free–Conditioned Medium Induce NSC Differentiation Into Neuron More Efficiently by the Upregulation of HIF-1 Alpha and Binding Activity
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