The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The Tissue-Engineered Auricle: Past, Present, and Future
Abstract
The reconstruction, repair, and regeneration of the external auricular framework continue to be one of the greatest challenges in the field of tissue engineering. To replace like with like, we should emulate the native structure and composition of auricular cartilage by combining a suitable chondrogenic cell source with an appropriate scaffold under optimal in vitro and in vivo conditions. Due to the fact that a suitable and reliable substitute for auricular cartilage has yet to be engineered, hand-carved autologous costal cartilage grafts and ear-shaped porous polyethylene implants are the current treatment modalities for auricular reconstruction. However, over the last decade, significant advances have been made in the field of regenerative medicine and tissue engineering. A variety of scaffolds and innovative approaches have been investigated as alternatives to using autologous carved costal cartilage or porous polyethylene implants. A review of recent developments and the current state of the art and science is presented, focusing on scaffolds, cell sources, seeding densities, and mechanical characteristics of tissue-engineered auricular cartilage.
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Citations
Cites
Fibrin: A versatile scaffold for tissue engineering applications
Ahmed, T. A. E., Dare, E. V., & Hincke, M. (2008) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2007.0435 · Cited by 994
Cited by
A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
Kang, H.-W., Lee, S. J., Ko, I. K., Kengla, C., Yoo, J. J., & Atala, A. (2016) · Nature Biotechnology · doi:10.1038/nbt.3413 · Cited by 2,622
Mannoor, M. S., Jiang, Z., James, T., Kong, Y. L., Malatesta, K. A., Soboyejo, W. O., Verma, N., Gracias, D. H., & McAlpine, M. C. (2013) · Nano Letters · doi:10.1021/nl4007744 · Cited by 874
3D printing to innovate biopolymer materials for demanding applications: A review
Li, N., Qiao, D., Zhao, S., Lin, Q., Zhang, B., & Xie, F. (2021) · Materials Today Chemistry · doi:10.1016/j.mtchem.2021.100459 · Cited by 142
Metadata
- Authors
- Bichara, D. A., O'Sullivan, N.-A., Pomerantseva, I., Zhao, X., Sundback, C. A., Vacanti, J. P., & Randolph, M. A.
- Venue
- Tissue Engineering Part B: Reviews
- Publisher
- SAGE Publications
- Published
- 2012-02
- Volume
- 18
- Issue
- 1
- Pages
- 51-61
- ISSN
- 1937-3368 (ISSN-L)
- 1937-3376
- OpenAlex
- W1999007447
- Cited by
- 169
- References
- 1
- FWCI
- 10.85
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bichara, D. A., O'Sullivan, N.-A., Pomerantseva, I., Zhao, X., Sundback, C. A., Vacanti, J. P., & Randolph, M. A. (2012). The Tissue-Engineered Auricle: Past, Present, and Future. Tissue Engineering Part B: Reviews. https://doi.org/10.1089/ten.teb.2011.0326
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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