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Aging of the Genome
Abstract
Preface 1. Introduction 2. The Logic of Aging 3. Genome Structure and Function 4. Genome Maintenance 5. Genome Instability and Accelerated Aging 6. The Aging Genome 7. From Genome to Phenome 8. A Genomic Limit to Life? References and Glossary Literature References
Overview
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Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Limits to the duration of life could well be determined by a set of species-specific, longevity-assurance systems encoded in the genome that counteract these inadvertent byproducts, which are likely to include inherent imperfections in transferring genetic information into cellular function13,14.”
From Evidence for a limit to human lifespan (2016) · cites this paper as [14]
In the citing paper
“Instead, what appears to be a ‘natural limit’ is an inadvertent byproduct of fixed genetic programs for early life events, such as development, growth and reproduction.”
From Evidence for a limit to human lifespan (2016) · cites this paper as [14]
In the citing paper
“In time, DNA injuries inevitably accumulate9 making genome instability a true hallmark of ageing (Figure 2).”
From The central role of DNA damage in the ageing process (2021) · cites this paper as [9]
Citations
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Cited by 63
Metadata
- Authors
- Vijg, J.
- Corresponding author
- Vijg, Jan
- ORCID
- Vijg, Jan
- Venue
- Oxford University Press eBooks
- Publisher
- Oxford University Press
- Published
- 2007-01-25
- OpenAlex
- W4205141611
- Cited by
- 63
- References
- 0
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 1 · 2022: 1 · 2021: 5 · 2019: 3 · 2018: 7 · 2017: 3 · 2016: 2 · 2015: 1 · 2014: 2 · 2013: 6 · 2012: 3
- FWCI
- 2.94
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- Oxford University Press eBooks (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Telomeres, Telomerase, and Senescence
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Keywords
- aging, genomic instability, DNA mutations, somatic cells, functional genomics, systems biology, age-related diseases, anti-aging strategies
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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