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A community-dwelling sample of people with Parkinson's disease: characteristics of fallers and non-fallers
Abstract
BACKGROUND: people with Parkinson's disease often fall. OBJECTIVES: to report the frequency of falls and characteristics of fallers and non-fallers in a community-based sample of people with Parkinson's disease. METHOD: we administered a battery of standardized tests in the home and the laboratory. RESULTS: we recruited 63 people with Parkinson's disease through general practices. Forty (64%, 95% confidence interval 51-74%) had fallen in the previous 12 months. Many factors associated with falling in the general population were associated with Parkinson's disease fallers (e.g. use of multiple medication and greater physical disability). Fallers were more likely to be depressed and anxious than non-fallers. Condition-specific factors associated with falling included greater disease severity (although there were exceptions) and more marked response to levodopa treatment, including more dyskinesia and on-off phenomena. Fallers took more steps to complete a test of mobility. They also had a shorter functional reach and greater postural sway whilst completing a dual task than non-fallers. CONCLUSION: this community-based study confirms the high risk of falling in Parkinson's disease. Our results suggest that disease-specific factors contribute to the increased risk and that there is scope for specific therapeutic interventions.
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Cited by
Tai chi and postural stability in patients with Parkinson's disease
Li, F., Harmer, P., Fitzgerald, K., Eckstrom, E., Stock, R., Galver, J., Maddalozzo, G., & Batya, S. S. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1107911 · Cited by 890
Rhythmic auditory stimulation modulates gait variability in Parkinson’s disease
Hausdorff, J. M., Lowenthal, J., Herman, T., Gruendlinger, L., Peretz, C., & Giladi, N. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05810.x · Cited by 489
Motor and cognitive outcome in patients with Parkinson's disease 8 years after subthalamic implants
Fasano, A., Romito, L. M., Daniele, A., Piano, C., Zinno, M., Bentivoglio, A. R., & Albanese, A. (2010) · Brain · doi:10.1093/brain/awq221 · Cited by 429
Pompeu, J. E., Mendes, F. A. D. S., Silva, K. G. D., Lobo, A. M., Oliveira, T. D. P., Zomignani, A. P., & Piemonte, M. E. P. (2012) · Physiotherapy · doi:10.1016/j.physio.2012.06.004 · Cited by 354
Limitations of current Parkinson's disease therapy
Rascol, O., Payoux, P., Ory, F., Ferreira, J. J., Brefel-Courbon, C., & Montastruc, J.-L. (2003) · Annals of Neurology · doi:10.1002/ana.10513 · Cited by 337
Metadata
- Authors
- Ashburn, A.
- Venue
- Age and Ageing
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-01-01
- Volume
- 30
- Issue
- 1
- Pages
- 47-52
- ISSN
- 0002-0729 (ISSN-L)
- 1468-2834
- OpenAlex
- W2119385988
- Cited by
- 330
- References
- 0
- FWCI
- 30.18
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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