The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Coronary heart disease: the zinc/copper hypothesis
Open accessAbstract
Epidemiologic and metabolic data are consanant with the hypothesis thata metabolic imbalance in regard to zinc and copper ia a major factor in the etiology of coronary heart disease. This metabolic imbalance is either a relative or an absoulte deficincey of copper characterized by a high ratio of zinc to copper. The imbalance results in hypercholesterolemia and increased mortaility die to coronary heart disease. The imbalance can occur due to the amounts of zince and copper in human food, to lack of protective substances in food or drinking water and to alterations in physiological status that produce adverse changes in the distribution of zinc and copper in certain important organs. Because no other agent, with the possible exception of cholesterol, has been related so closely to tisk, the ratio of zinc to copper may be the preponderant factor in the etiology of coronary heart disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mitchell, H. H., & Hamilton, T. S. (1949) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)56964-7 · Cited by 192
Cited by
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
Fardet, A. (2010) · Nutrition Research Reviews · doi:10.1017/s0954422410000041 · Cited by 1,030
Metabolic effects of dietary fructose
Hallfrisch, J. (1990) · The FASEB Journal · doi:10.1096/fasebj.4.9.2189777 · Cited by 357
Serum zinc and serum lipid profiles in 778 adults
Hiller, R., Seigel, D., Sperduto, R. D., Blair, N., Burton, T. C., Farber, M. D., Gragoudas, E. S., Gunter, E. W., Haller, J., Seddon, J. M., et al. (1995) · Annals of Epidemiology · doi:10.1016/1047-2797(95)00066-6 · Cited by 28
Metadata
- Authors
- Klevay, L.
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1975-07
- Volume
- 28
- Issue
- 7
- Pages
- 764-774
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W1927102686
- Cited by
- 258
- References
- 1
- FWCI
- 10.04
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Coronary heart disease: the zinc/copper hypothesis. https://app.cochat.ai/papers/10.1093/ajcn/28.7.764
- The paper
- Klevay, L. (1975). Coronary heart disease: the zinc/copper hypothesis. The American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/28.7.764
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
