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Cited by 133Obesity, Physical Activity, DietCardiovascular and exercise physiologyMuscle metabolism and nutrition

Effects of a very-low-calorie diet and physical-training regimens on body composition and resting metabolic rate in obese females

Donnelly, JE, Pronk, NP, Jacobsen, DJ, Pronk, SJ, Jakicic, JM·1991·The American Journal of Clinical Nutrition
DOI 10.1093/ajcn/54.1.56
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Abstract

Sixty-nine obese females received 90 d of a liquid diet providing 2184 kJ/d in clinical trials. Groups were diet only (C), diet plus endurance exercise (EE), diet plus weight training (WT), or diet plus endurance exercise and weight training (EEWT). Changes in body weight, percent fat, fat weight, and fat-free mass were not different between groups. Declines in resting metabolic rate (RMR) were approximately 7% to approximately 12% of baseline values with no differences among groups. A significant increase in work capacity (approximately 16%) was shown for EEWT. Strength index showed declines of approximately 6% for C and EE and gains of approximately 3% and approximately 10% for EEWT and WT, respectively. These clinical trials did not show advantages of any exercise regimen over diet alone for weight loss, body-composition changes, or declines in RMR. Improvements in work capacity were limited and strength improved in groups that participated in strength training.

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Crossref · 10.1093/ajcn/54.1.56

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  • In response to a very-low-calorie diet that induced the loss of about 20% of baseline weight, the addition of structured exercise did not preserve lean mass significantly better than the very-low-calorie diet alone.

    “For example, in response to a very-low-calorie diet (VLCD), which induced the loss of ~ 20% of baseline weight (~ 20 kg), the addition of structured exercise (i.e., randomization to aerobic, resistance, or aerobic plus resistance groups) did not preserve lean mass significantly better than the VLCD alone [94].”

    From The Role of Lifestyle Modification with Second-Generation Anti-obesity Medications: Comparisons, Questions, and Clinical Opportunities (2023) · cites this paper as [94]

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Authors
Donnelly, J., Pronk, N., Jacobsen, D., Pronk, S., & Jakicic, J.
Affiliations
University of Nebraska at Kearney (US)
Venue
The American Journal of Clinical Nutrition
Publisher
Elsevier BV
Published
1991-07
Volume
54
Issue
1
Pages
56-61
ISSN
0002-9165 (ISSN-L)
DOI
10.1093/ajcn/54.1.56
OpenAlex
W2098786382
Cited by
133
References
48
Citations by year
2026: 1 · 2025: 4 · 2024: 1 · 2023: 4 · 2020: 1 · 2019: 1 · 2018: 2 · 2017: 7 · 2016: 4 · 2015: 5 · 2014: 2 · 2013: 4 · 2012: 5
FWCI
9.16
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • American Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (1r15dk038899-01)
  • National Institute of Diabetes and Digestive and Kidney Diseases (1R15DK38899-01)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
Keywords
very low calorie diet, obesity, obese women, resting metabolic rate, body composition, weight loss, endurance exercise, weight training, resistance training, work capacity, strength index, fat-free mass, liquid diet
MeSH terms
Basal Metabolism, Body Composition, Energy Intake, Diet, Reducing, Female, Humans, Obesity, Oxygen Consumption, Weight Loss, Exercise

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