Effect of physical activity on weight loss, energy expenditure, and energy intake during diet induced weight loss: Effects of Physical Activity During Intervention
Open accessAbstract
OBJECTIVE: Objective measurements of physical activity (PA), energy expenditure (EE) and energy intake can provide valuable information regarding appropriate strategies for successful sustained weight loss. DESIGN AND METHODS: The total EE was examined by doubly labeled water, resting metabolic rate by indirect calorimetry, PA with activity monitors, and energy intake by the intake/balance technique in 116 severely obese undergoing intervention with diet alone (DO) or diet plus PA (D-PA). RESULTS: Weight loss of 9.6 ± 6.8 kg resulted in decreased EE which was not minimized in the D-PA group. Comparing the highest and lowest quartiles of increase in PA revealed a lower decrease in TDEE (-122 ± 319 vs. -376 ± 305 kcal day⁻¹), elimination of the drop in AEE (83 ± 279 vs. -211 ± 284 kcal day⁻¹) and greater weight loss (13.0 ± 7.0 vs. 8.1 ± 6.3 kg). Increased PA was associated with greater adherence to energy restriction and maintenance of greater weight loss during months 7-12. CONCLUSION: Noncompliance to prescribed PA in the DO and D-PA groups partially masked the effects of PA to increase weight loss and to minimize the reduced EE. Increased PA was also associated with improved adherence to prescribed caloric restriction. A strong recommendation needs to be made to improve interventions that promote PA within the context of behavioral weight loss interventions.
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Interventions that reduce body weight by as little as 5% can reduce obesity-related metabolic disorders.
“Interventions that reduce body weight by as little as 5%, however, can reduce obesity-related metabolic disorders (217).”
From Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease (2018) · cites this paper as [217]
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Metabolic Flexibility as an Adaptation to Energy Resources and Requirements in Health and Disease
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Self-citation
- Authors
- DeLany, J. P., Kelley, D. E., Hames, K. C., Jakicic, J. M., & Goodpaster, B. H.
- Affiliations
- University of Pittsburgh (US)
- Corresponding author
- DeLany, James P.
- Venue
- Obesity
- Publisher
- Wiley
- Published
- 2013-08-23
- Volume
- 22
- Issue
- 2
- Pages
- 363-370
- ISSN
- 1930-7381 (ISSN-L)
- PMC
- PMC4896218
- OpenAlex
- W1547641686
- Cited by
- 60
- References
- 41
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 6 · 2022: 3 · 2021: 4 · 2020: 1 · 2019: 5 · 2018: 6 · 2017: 9 · 2016: 5 · 2015: 10 · 2014: 6 · 2013: 1
- FWCI
- 7.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Obesity (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- University of Pittsburgh
- National Institutes of Health (5p30dk046204-15)
- National Institute on Aging (P30AG024827)
- National Institute of Diabetes and Digestive and Kidney Diseases (P30-DK046204)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Keywords
- physical activity, diet-induced weight loss, energy expenditure, energy intake, morbid obesity, resting metabolic rate, total energy expenditure, physical activity energy expenditure, weight loss maintenance, behavioral weight loss
- MeSH terms
- Adult, Behavior Therapy, Energy Intake, Combined Modality Therapy, Diet, Reducing, Energy Metabolism, Fatty Liver, Female, Humans, Liver, Male, Middle Aged, Motor Activity, Obesity, Morbid, Patient Compliance, Pennsylvania, Weight Loss, Body Mass Index, Walking, Monitoring, Ambulatory, Intra-Abdominal Fat, Adiposity
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