Plasma cholesterol-predictive equations demonstrate that stearic acid is neutral and monounsaturated fatty acids are hypocholesterolemic
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Predictive regression equations generally include regression coefficients showing that SFA increases LDL cholesterol twice as much as PUFA reduces LDL cholesterol.
“These equations generally include regression coefficients that show SFA increases LDL cholesterol twice as much as PUFA reduces LDL cholesterol [[12], [13], [14]].”
Cites
JACOBS, D. R., MEBANE, I. L., BANGDIWALA, S. I., CRIQUI, M. H., TYROLER, H. A., & PROGRAM, F. T. L. R. C. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115483 · Cited by 452 · see citing works
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Types of Dietary Fat and Risk of Coronary Heart Disease: A Critical Review
Hu, F. B., Manson, J. E., & Willett, W. C. (2001) · Journal of the American College of Nutrition · doi:10.1080/07315724.2001.10719008 · Cited by 902 · see citing works
Hu, F. B., Stampfer, M. J., Manson, J. E., Ascherio, A., Colditz, G. A., Speizer, F. E., Hennekens, C. H., & Willett, W. C. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.6.1001 · Cited by 661 · see citing works
Yu-Poth, S., Zhao, G., Etherton, T., Naglak, M., Jonnalagadda, S., & Kris-Etherton, P. M. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.4.632 · Cited by 584 · see citing works
Self-citationKris-Etherton, P. M., Yu-Poth, S., Sabaté, J., Ratcliffe, H. E., Zhao, G., & Etherton, T. D. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.3.504s · Cited by 339 · see citing works
Self-citationGuasch-Ferré, M., Babio, N., Martínez-González, M. A., Corella, D., Ros, E., Martín-Peláez, S., Estruch, R., Arós, F., Gómez-Gracia, E., Fiol, M., et al. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.116046 · Cited by 313 · see citing works
Dreon, D., Fernstrom, H., Campos, H., Blanche, P., Williams, P., & Krauss, R. (1998) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/67.5.828 · Cited by 170 · see citing works
Olive oil and cardiovascular health
Covas, M.-I., Konstantinidou, V., & Fitó, M. (2009) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e3181c5e7fd · Cited by 158 · see citing works
Hart, T. L., Damani, J. J., DiMattia, Z. S., Tate, K. E., Jafari, F., & Petersen, K. S. (2025) · Advances in Nutrition · doi:10.1016/j.advnut.2025.100502 · Cited by 16 · see citing works
“These equations generally include regression coefficients that show SFA increases LDL cholesterol twice as much as PUFA reduces LDL cholesterol [12 – 14].”
- Authors
- Yu, S., Derr, J., Etherton, T., & Kris-Etherton, P.
- Affiliations
- Pennsylvania State University (US)
- ORCID
- Kris-Etherton, PM
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1995-05
- Volume
- 61
- Issue
- 5
- Pages
- 1129-1139
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W4300303469
- Cited by
- 316
- References
- 1
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 4 · 2022: 7 · 2021: 9 · 2020: 9 · 2019: 8 · 2018: 10 · 2017: 11 · 2016: 9 · 2015: 14 · 2014: 7 · 2013: 12 · 2012: 14
- FWCI
- 12.26
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Clinical Nutrition (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Surgery › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Keywords
- stearic acid, monounsaturated fatty acids, polyunsaturated fatty acids, saturated fatty acids, total cholesterol, LDL cholesterol, HDL cholesterol, cholesterol-lowering effect, dietary fatty acids
- MeSH terms
- Adult, Aged, Anticholesteremic Agents, Cholesterol, Fatty Acids, Monounsaturated, Fatty Acids, Unsaturated, Female, Humans, Lipids, Lipoproteins, Cholesterol, HDL, Cholesterol, LDL, Male, Mathematics, Middle Aged, Models, Biological, Predictive Value of Tests, Regression Analysis, Stearic Acids
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