The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Copper biochemistry and molecular biology
Open accessAbstract
In this review, our basic and most recent understanding of copper biochemistry and molecular biology for mammals (including humans) is described. Information is provided on the nutritional biochemistry of copper, including food sources, intestinal absorption, transport, tissue distribution, and excretion, along with descriptions of copper binding proteins and other factors involved and their roles in these processes. The metabolism of copper and its importance for the functions of a roster of vital enzymes is detailed. Its potential toxicology is also addressed. Alterations in copper metabolism associated with genetic and nongenetic diseases are summarized, including potential connections to inflammation, cancer, atherosclerosis, and anemia, and the effects of genetic copper deficiency (Menkes syndrome) and copper overload (Wilson disease). Understanding these diseases suggests new ways of viewing the normal functions of copper and provides new insights into the details of copper transport and distribution in mammals.
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The FET3 gene of S. cerevisiae encodes a multicopper oxidase required for ferrous iron uptake.
Askwith, C., Eide, D., Van Ho, A., Bernard, P. S., Li, L., Davis-Kaplan, S., Sipe, D. M., & Kaplan, J. (1994) · Cell · doi:10.1016/0092-8674(94)90346-8 · Cited by 670
Aceruloplasminemia: molecular characterization of this disorder of iron metabolism.
Harris, Z. L., Takahashi, Y., Miyajima, H., Serizawa, M., MacGillivray, R. T., & Gitlin, J. D. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.7.2539 · Cited by 558
A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans
Yoshida, K., Furihata, K., Takeda, S., Nakamura, A., Yamamoto, K., Morita, H., Hiyamuta, S., Ikeda, S.-I., Shimizu, N., & Yanagisawa, N. (1995) · Nature Genetics · doi:10.1038/ng0395-267 · Cited by 463
Cited by
Contribution of Selected Vitamins and Trace Elements to Immune Function
Wintergerst, E. S., Maggini, S., & Hornig, D. H. (2007) · Annals of Nutrition and Metabolism · doi:10.1159/000107673 · Cited by 692
The redox chemistry of the Alzheimer's disease amyloid β peptide
Smith, D. G., Cappai, R., & Barnham, K. J. (2007) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2007.02.002 · Cited by 608
h CTR1: A human gene for copper uptake identified by complementation in yeast
Zhou, B., & Gitschier, J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7481 · Cited by 567
Market basket survey for some heavy metals in Egyptian fruits and vegetables
Radwan, M. A., & Salama, A. K. (2006) · Food and Chemical Toxicology · doi:10.1016/j.fct.2006.02.004 · Cited by 561
Arredondo, M., & Núñez, M. T. (2005) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2005.07.010 · Cited by 550
Metadata
- Authors
- Linder, M. C., & Hazegh-Azam, M.
- Venue
- The American Journal of Clinical Nutrition
- Publisher
- Elsevier BV
- Published
- 1996-05
- Volume
- 63
- Issue
- 5
- Pages
- 797S-811S
- ISSN
- 0002-9165 (ISSN-L)
- OpenAlex
- W1926541489
- Cited by
- 1,430
- References
- 5
- FWCI
- 25.22
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Linder, M. C., & Hazegh-Azam, M. (1996). Copper biochemistry and molecular biology. The American Journal of Clinical Nutrition. https://doi.org/10.1093/ajcn/63.5.797
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
