CoChat
Sign Up
Cited by 267Bone health and osteoporosis researchNutritional Studies and DietNutrition and Health Studies

Fruit and vegetable intakes and bone mineral status: A cross sectional study in 5 age and sex cohorts

Open access
Prynne, Celia J, Mishra, Gita D, O’Connell, Maria A, Muniz, Graciela, Laskey, M Ann, Yan, Liya, Prentice, Ann, Ginty, Fiona·2006·The American Journal of Clinical Nutrition
DOI 10.1093/ajcn/83.6.1420
Open this paper in CoChat — free accountOpen PDF

Abstract

Background Evidence is increasing for positive effects of fruit and vegetable intakes on bone health. However, most of the studies to date were conducted in adults, and few reports included adolescents.Objective We explored the association between bone mineral status and fruit and vegetable intakes in adolescent boys and girls (aged 16-18 y), young women (aged 23-37 y), and older men and women (aged 60-83 y).Design Bone mineral measurements of the whole body, hip, and spine were made in all subjects by using dual-energy X-ray absorptiometry. Information on health and lifestyle and physical activity was obtained by questionnaire. Fruit, vegetable, and nutrient intakes were ascertained from 7-d food diaries.Results In adolescent boys and girls and older women, significant positive associations were observed between spine size-adjusted bone mineral content (SA-BMC) and fruit intake. In boys only, femoral neck SA-BMC was also significantly and positively associated with the intakes of both fruit and dietary vitamin C. No significant associations were found in the young women or older men, or between bone measurements and intake of vegetables alone (after adjustments) in any of the groups.Conclusions Higher fruit and vegetable intakes may have positive effects on bone mineral status in both younger and older age groups, especially at the spine and femoral neck. The specific mechanisms remain to be ascertained, but vitamin C, other fruit-specific antioxidants, and lifestyle may play a role.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/ajcn/83.6.1420

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Organic nitrate NO donors such as glycerol trinitrate, isosorbide dinitrate, and mononitrate all have beneficial effects on experimental and clinical osteoporosis, and a number of epidemiological studies indicated that high fruit and vegetable intake appears protective against osteoporosis in men and pre- and postmenopausal women.

    “In this context, it has been shown that organic nitrate NO donors, such as glycerol trinitrate, isosorbide dinitrate and mononitrate all have beneficial effects on experimental and clinical osteoporosis [161,162,163], and a number of epidemiological studies also indicated that a high fruit and vegetable intake appears to have a protective effect against osteoporosis in men and pre- and post”

    From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [164]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 3

  1. All values are x ; 95% CI in parentheses. Fruit intake and total daily intake of nutrients were assessed from a 7-d diary. Median intakes were 34, 140, and 306 g/d in boys and 40, 134, and 334 g/d in girls in T1, T2, and T3, respectively. ANOVA was used to compare the mean intakes of energy and selected nutrients by thirds of fruit intake. Means in a row with different superscript letters are significantly different, P 0.05 (Scheffe's test). 2 Geometric x . REFERENCES
  2. Cole T. Sympercents; symmetric percentage differences on the 100 log(e) scale simplify the presentation of log transformed data. Stat Med 2000;19:3109 -25.
  3. Ginty F, Prynne CJ, Muniz G, et al. No evidence for a negative associ- ation between bone mineral status and indirect estimates of renal net acid excretion in younger and older age groups. Proc Nutr Soc 2006;64:80A (abstr).

Cited by

Sorted by citations

Related

Authors
Prynne, C. J., Mishra, G. D., O’Connell, M. A., Muniz, G., Laskey, M. A., Yan, L., Prentice, A., & Ginty, F.
Affiliations
MRC Elsie Widdowson Laboratory (GB)
Corresponding author
Prynne, Celia J
ORCID
Venue
The American Journal of Clinical Nutrition
Publisher
Elsevier BV
Published
2006-06
Volume
83
Issue
6
Pages
1420-1428
ISSN
0002-9165 (ISSN-L)
DOI
10.1093/ajcn/83.6.1420
OpenAlex
W2143398835
Cited by
267
References
45
Citations by year
2026: 2 · 2025: 4 · 2024: 7 · 2023: 5 · 2022: 3 · 2021: 14 · 2020: 14 · 2019: 14 · 2018: 17 · 2017: 12 · 2016: 16 · 2015: 12 · 2014: 14 · 2013: 15 · 2012: 22
FWCI
18.33
Type
journal article
Language
en
Open access
Licence
Locations
  • American Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
  • UEA Digital Repository (University of East Anglia) (acceptedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Funders
Medical Research Council
Topics
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
Keywords
fruit consumption, vegetable consumption, bone mineral status, bone mineral content, adolescents, older adults, young women, vitamin C, femoral neck, spine, hip, dietary antioxidants, physical activity
MeSH terms
Adolescent, Adult, Aged, Antioxidants, Ascorbic Acid, Energy Intake, Cross-Sectional Studies, Diet, Diet Surveys, Female, Fruit, Humans, Life Style, Male, Middle Aged, Vegetables, Multicenter Studies as Topic, Bone Density, Age Distribution, Sex Distribution

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review