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Cited by 785

The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.

COVID-19 in Health-Care Workers: A Living Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes

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Gómez-Ochoa, Sergio Alejandro, Franco, Oscar H, Rojas, Lyda Z, Raguindin, Peter Francis, Roa-Díaz, Zayne Milena, Wyssmann, Beatrice Minder, Guevara, Sandra Lucrecia Romero, Echeverría, Luis Eduardo, Glisic, Marija, Muka, Taulant·2021·American Journal of Epidemiology
DOI 10.1093/aje/kwaa191
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Abstract

Health-care workers (HCWs) are at the frontline of response to coronavirus disease 2019 (COVID-19), being at a higher risk of acquiring the disease and, subsequently, exposing patients and others. Searches of 8 bibliographic databases were performed to systematically review the evidence on the prevalence, risk factors, clinical characteristics, and prognosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among HCWs. A total of 97 studies (all published in 2020) met the inclusion criteria. The estimated prevalence of SARS-CoV-2 infection from HCWs’ samples, using reverse transcription–polymerase chain reaction and the presence of antibodies, was 11% (95% confidence interval (CI): 7, 15) and 7% (95% CI: 4, 11), respectively. The most frequently affected personnel were nurses (48%, 95% CI: 41, 56), whereas most of the COVID-19–positive medical personnel were working in hospital nonemergency wards during screening (43%, 95% CI: 28, 59). Anosmia, fever, and myalgia were the only symptoms associated with HCW SARS-CoV-2 positivity. Among HCWs positive for COVID-19 by reverse transcription–polymerase chain reaction, 40% (95% CI: 17, 65) were asymptomatic at time of diagnosis. Finally, severe clinical complications developed in 5% (95% CI: 3, 8) of the COVID-19–positive HCWs, and 0.5% (95% CI: 0.02, 1.3) died. Health-care workers suffer a significant burden from COVID-19, with those working in hospital nonemergency wards and nurses being the most commonly infected personnel.

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Metadata

Authors
Gómez-Ochoa, S. A., Franco, O. H., Rojas, L. Z., Raguindin, P. F., Roa-Díaz, Z. M., Wyssmann, B. M., Guevara, S. L. R., Echeverría, L. E., Glisic, M., & Muka, T.
Venue
American Journal of Epidemiology
Publisher
Oxford University Press (OUP)
Published
2020-09-01
Volume
190
Issue
1
Pages
161-175
ISSN
  • 0002-9262 (ISSN-L)
  • 1476-6256
DOI
10.1093/aje/kwaa191
OpenAlex
W3082291084
Cited by
785
References
92
FWCI
8.45
Type
journal article
Language
en
Open access
bronze
Licence
academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)

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CoChat. (2026). Citation check: COVID-19 in Health-Care Workers: A Living Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes. https://app.cochat.ai/papers/10.1093/aje/kwaa191
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Gómez-Ochoa, S. A., Franco, O. H., Rojas, L. Z., Raguindin, P. F., Roa-Díaz, Z. M., Wyssmann, B. M., Guevara, S. L. R., Echeverría, L. E., Glisic, M., & Muka, T. (2021). COVID-19 in Health-Care Workers: A Living Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwaa191

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