Cited by 163Nutritional Studies and DietSodium Intake and HealthBlood Pressure and Hypertension Studies

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The Mediterranean Diet and Incidence of Hypertension: The Seguimiento Universidad de Navarra (SUN) Study

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Nunez-Cordoba, J. M., Valencia-Serrano, F., Toledo, E., Alonso, A., Martinez-Gonzalez, M. A.·2008·American Journal of Epidemiology

DOI 10.1093/aje/kwn335

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Abstract

The Mediterranean diet is receiving increasing attention in cardiovascular epidemiology. The association of adherence to the Mediterranean diet with the incidence of hypertension was evaluated among 9,408 men and women enrolled in a dynamic Spanish prospective cohort study during 1999-2005. Dietary intake was assessed at baseline with a validated semiquantitative food frequency questionnaire, and a 9-point Mediterranean diet score was constructed. During a median follow-up period of 4.2 years (range, 1.9-7.9), 501 incident cases of hypertension were identified. After adjustment for major hypertension risk factors and nutritional covariates, adherence to the Mediterranean diet was not associated with hypertension (the hazard ratio was 1.10 (95% confidence interval (CI): 0.81, 1.41) for moderate adherence and 1.12 (95% CI: 0.79, 1.60) for high adherence). However, it was associated with reduced changes in mean levels of systolic blood pressure (moderate adherence, -2.4 mm Hg (95% CI: -4.0, -0.8); high adherence, -3.1 mm Hg (95% CI: -5.4, -0.8)) and diastolic blood pressure (moderate adherence, -1.3 mm Hg (95% CI: -2.5, -0.1); high adherence, -1.9 mm Hg (95% CI: -3.6, -0.1)) after 6 years of follow-up. These results suggest that adhering to a Mediterranean-type diet could contribute to the prevention of age-related changes in blood pressure.

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Authors: Nunez-Cordoba, J. M., Valencia-Serrano, F., Toledo, E., Alonso, A., & Martinez-Gonzalez, M. A.
ORCID: Toledo, E.
Venue: American Journal of Epidemiology
Publisher: Oxford University Press (OUP)
Published: 2008-11-25
Volume: 169
Issue: 3
Pages: 339-346
ISSN: 0002-9262 (ISSN-L)
1476-6256
DOI: 10.1093/aje/kwn335
OpenAlex: W2155218187
Cited by: 163
References: 41
Citations by year: 2026: 1 · 2025: 2 · 2024: 8 · 2023: 4 · 2022: 7 · 2021: 5 · 2020: 17 · 2019: 10 · 2018: 10 · 2017: 11 · 2016: 8 · 2015: 3 · 2014: 14 · 2013: 16 · 2012: 14
FWCI: 10.60
Type: journal article
Language: en
Open access: green
hdl.handle.net
Licence: other-oa
Locations: American Journal of Epidemiology (publishedVersion)
PubMed (publishedVersion)
Deposito Adademico Digital Universidad De Navarra (University of Navarra) (submittedVersion, other-oa)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Keywords: Mediterranean diet, hypertension incidence, dietary adherence, Mediterranean diet score, systolic blood pressure, diastolic blood pressure, blood pressure changes, hypertension prevention, Seguimiento Universidad de Navarra cohort
MeSH terms: Adult, Energy Intake, Female, Humans, Hypertension, Longitudinal Studies, Male, Spain, Incidence, Diet, Mediterranean

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The Mediterranean Diet and Incidence of Hypertension: The Seguimiento Universidad de Navarra (SUN) Study

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