The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Prediction of Incident Stroke Events Based on Retinal Vessel Caliber: A Systematic Review and Individual-Participant Meta-Analysis
Open accessAbstract
The caliber of the retinal vessels has been shown to be associated with stroke events. However, the consistency and magnitude of association, and the changes in predicted risk independent of traditional risk factors, are unclear. To determine the association between retinal vessel caliber and the risk of stroke events, the investigators combined individual data from 20,798 people, who were free of stroke at baseline, in 6 cohort studies identified from a search of the Medline (National Library of Medicine, Bethesda, Maryland) and EMBASE (Elsevier B.V., Amsterdam, the Netherlands) databases. During follow-up of 5-12 years, 945 (4.5%) incident stroke events were recorded. Wider retinal venular caliber predicted stroke (pooled hazard ratio = 1.15, 95% confidence interval: 1.05, 1.25 per 20-micron increase in caliber), but the caliber of retinal arterioles was not associated with stroke (pooled hazard ratio = 1.00, 95% confidence interval: 0.92, 1.08). There was weak evidence of heterogeneity in the hazard ratio for retinal venular caliber, which may be attributable to differences in follow-up strategies across studies. Inclusion of retinal venular caliber in prediction models containing traditional stroke risk factors reassigned 10.1% of people at intermediate risk into different, mostly lower, risk categories.
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Cites
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Cited by
(2013) · European Heart Journal · doi:10.1093/eurheartj/eht151 · Cited by 13,655
Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., Christiaens, T., Cifkova, R., De Backer, G., Dominiczak, A., et al. (2013) · Journal of Hypertension · doi:10.1097/01.hjh.0000431740.32696.cc · Cited by 5,655
Prediction of cardiovascular risk factors from retinal fundus photographs via deep learning
Poplin, R., Varadarajan, A. V., Blumer, K., Liu, Y., McConnell, M. V., Corrado, G. S., Peng, L., & Webster, D. R. (2018) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0195-0 · Cited by 1,865
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Doppler Optical Coherence Tomography
Leitgeb, R. A., Werkmeister, R. M., Blatter, C., & Schmetterer, L. (2014) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2014.03.004 · Cited by 444
Metadata
- Authors
- McGeechan, K., Liew, G., Macaskill, P., Irwig, L., Klein, R., Klein, B. E. K., Wang, J. J., Mitchell, P., Vingerling, J. R., de Jong, P. T. V. M., Witteman, J. C. M., Breteler, M. M. B., Shaw, J., Zimmet, P., & Wong, T. Y.
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-11-01
- Volume
- 170
- Issue
- 11
- Pages
- 1323-1332
- ISSN
- 0002-9262 (ISSN-L)
- 1476-6256
- OpenAlex
- W2138530279
- Cited by
- 347
- References
- 4
- FWCI
- 1.86
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Prediction of Incident Stroke Events Based on Retinal Vessel Caliber: A Systematic Review and Individual-Participant Meta-Analysis. https://app.cochat.ai/papers/10.1093/aje/kwp306
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- McGeechan, K., Liew, G., Macaskill, P., Irwig, L., Klein, R., Klein, B. E. K., Wang, J. J., Mitchell, P., Vingerling, J. R., de Jong, P. T. V. M., Witteman, J. C. M., Breteler, M. M. B., Shaw, J., Zimmet, P., & Wong, T. Y. (2009). Prediction of Incident Stroke Events Based on Retinal Vessel Caliber: A Systematic Review and Individual-Participant Meta-Analysis. American Journal of Epidemiology. https://doi.org/10.1093/aje/kwp306
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
