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Do Co-morbid Anxiety Disorders Predict Drinking Outcomes in Women with Alcohol Use Disorders?
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AIMS: It is unclear whether co-morbid anxiety disorders predict worse drinking outcomes during attempts to change drinking behavior. Studies have yielded mixed results, and have rarely examined drinking outcomes based on a specific type of anxiety disorder. Women with alcohol use disorders (AUDs) are of particular interest as they are at risk for co-morbid anxiety [Kessler et al. (1997) Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the national co-morbidity survey. Arch Gen Psychiat 54:313-21]. METHODS: Participants were 260 women with AUDs participating in an alcohol-treatment outcome studies. The Timeline Follow-Back was used to assess drinking frequency (percent days drinking) prior, within and 6 months post-treatment. The current study tested the hypothesis that having at least one lifetime anxiety disorder diagnosed at baseline using the Structured Clinical Interview for DSM Disorders would be associated with more drinking at all study time points. Exploratory analyses examined patterns of drinking outcomes by specific anxiety diagnoses. RESULTS: Lifetime anxiety diagnosis was linked to poorer drinking outcomes post-treatment (β = 0.15, P = 0.020), despite less frequent drinking prior to treatment. Analyses by specific anxiety diagnosis indicated that generalized anxiety disorder predicted poorer drinking outcomes within treatment (β = 0.14, P = 0.018) and during follow-up (β = 0.16, P = 0.014). CONCLUSION: Co-morbid anxiety problems complicate treatment for AUDs among women. Further, specific anxiety disorders should be evaluated as distinct constructs as evidenced by the differential outcomes related to generalized anxiety disorder. Implications for treatment development for women with AUDs are discussed.
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Co-occurring alcohol use and anxiety disorders commonly lead to greater severity and impairment, and poorer treatment response than either disorder in isolation.
“This complex, mutually exacerbating relationship commonly leads to greater severity and impairment, as well as a poorer response to treatment than for either disorder in isolation (Farris et al., 2012; McEvoy and Shand, 2008).”
From Acceptability and Co-Development of an Online Cognitive Bias Modification Intervention for Emerging Adults With Hazardous Alcohol Use and Social Anxiety: A Mixed Methods Study (2020) · cites this paper as Farris et al., 2012
The Introduction associates co-morbid anxiety with increased substance-use severity, and the Discussion reports poorer drinking outcomes among women with AUDs and anxiety than among women with AUDs alone. The paper does not establish greater impairment or compare the co-occurring disorders with anxiety alone. It also reports less frequent drinking before treatment in the co-morbid group, so the broad claim of greater severity needs qualification. (LLM, conf=0.86)
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Metadata
- Authors
- Farris, S. G., Epstein, E. E., McCrady, B. S., & Hunter-Reel, D.
- Affiliations
- Rutgers, The State University of New Jersey (US)
- University of New Mexico (US)
- Venue
- Alcohol and Alcoholism
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-01-02
- Volume
- 47
- Issue
- 2
- Pages
- 143-148
- ISSN
- 0735-0414 (ISSN-L)
- 1464-3502
- PMC
- PMC3284684
- OpenAlex
- W2000378858
- Cited by
- 38
- References
- 35
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 6 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 5 · 2019: 4 · 2018: 1 · 2017: 1 · 2015: 4 · 2014: 4 · 2012: 3
- FWCI
- 2.63
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Alcohol and Alcoholism (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (R37-AA07070, T32AA007569, R37AA007070, T32-AA07569)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Keywords
- anxiety disorders, alcoholism, women, generalized anxiety disorder, drinking outcomes, alcohol treatment, comorbidities, relapse, drinking frequency
- MeSH terms
- Alcohol Drinking, Anxiety Disorders, Female, Health Surveys, Humans, Middle Aged, Comorbidity, Randomized Controlled Trials as Topic, Treatment Outcome, Diagnosis, Dual (Psychiatry), Alcohol-Related Disorders
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