The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Using Tablet for visual exploration of second-generation sequencing data
Open accessAbstract
The advent of second-generation sequencing (2GS) has provided a range of significant new challenges for the visualization of sequence assemblies. These include the large volume of data being generated, short-read lengths and different data types and data formats associated with the diversity of new sequencing technologies. This article illustrates how Tablet-a high-performance graphical viewer for visualization of 2GS assemblies and read mappings-plays an important role in the analysis of these data. We present Tablet, and through a selection of use cases, demonstrate its value in quality assurance and scientific discovery, through features such as whole-reference coverage overviews, variant highlighting, paired-end read mark-up, GFF3-based feature tracks and protein translations. We discuss the computing and visualization techniques utilized to provide a rich and responsive graphical environment that enables users to view a range of file formats with ease. Tablet installers can be freely downloaded from http://bioinf.hutton.ac.uk/tablet in 32 or 64-bit versions for Windows, OS X, Linux or Solaris. For further details on the Tablet, contact tablet@hutton.ac.uk.
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Self-citation
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Metadata
- Authors
- Milne, I., Stephen, G., Bayer, M., Cock, P. J. A., Pritchard, L., Cardle, L., Shaw, P. D., & Marshall, D.
- Venue
- Briefings in Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-03-24
- Volume
- 14
- Issue
- 2
- Pages
- 193-202
- ISSN
- 1467-5463 (ISSN-L)
- 1477-4054
- OpenAlex
- W2138618895
- Cited by
- 973
- References
- 5
- FWCI
- 17.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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