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Cited by 1,574

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Seq-Gen: an application for the Monte Carlo simulation of DNA sequence evolution along phylogenetic trees

Open access
Rambaut, Andrew, Grass, Nicholas C.·1997·Bioinformatics

Abstract

MOTIVATION: Seq-Gen is a program that will simulate the evolution of nucleotide sequences along a phylogeny, using common models of the substitution process. A range of models of molecular evolution are implemented, including the general reversible model. Nucleotide frequencies and other parameters of the model may be given and site-specific rate heterogeneity can also be incorporated in a number of ways. Any number of trees may be read in and the program will produce any number of data sets for each tree. Thus, large sets of replicate simulations can be easily created. This can be used to test phylogenetic hypotheses using the parametric bootstrap. AVAILABILITY: Seq-Gen can be obtained by WWW from http:/(/)evolve.zoo.ox.ac.uk/Seq-Gen/seq-gen.html++ + or by FTP from ftp:/(/)evolve.zoo.ox.ac.uk/packages/Seq-Gen/. The package includes the source code, manual and example files. An Apple Macintosh version is available from the same sites.

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Crossref · 10.1093/bioinformatics/13.3.235

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Metadata

Authors
Rambaut, A., & Grass, N. C.
Venue
Bioinformatics
Published
1997
Volume
13
Issue
3
Pages
235-238
ISSN
  • 0266-7061 (ISSN-L)
  • 1367-4803
  • 1460-2059
OpenAlex
W2125359798
Cited by
1,574
References
7
FWCI
4.72
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Seq-Gen: an application for the Monte Carlo simulation of DNA sequence evolution along phylogenetic trees. https://app.cochat.ai/papers/10.1093/bioinformatics/13.3.235
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Rambaut, A., & Grass, N. C. (1997). Seq-Gen: an application for the Monte Carlo simulation of DNA sequence evolution along phylogenetic trees. Bioinformatics. https://doi.org/10.1093/bioinformatics/13.3.235

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