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AWTY (are we there yet?): a system for graphical exploration of MCMC convergence in Bayesian phylogenetics

Open access
Nylander, Johan A.A., Wilgenbusch, James C., Warren, Dan L., Swofford, David L.·2008·Bioinformatics

Abstract

Summary: A key element to a successful Markov chain Monte Carlo (MCMC) inference is the programming and run performance of the Markov chain. However, the explicit use of quality assessments of the MCMC simulations—convergence diagnostics—in phylogenetics is still uncommon. Here, we present a simple tool that uses the output from MCMC simulations and visualizes a number of properties of primary interest in a Bayesian phylogenetic analysis, such as convergence rates of posterior split probabilities and branch lengths. Graphical exploration of the output from phylogenetic MCMC simulations gives intuitive and often crucial information on the success and reliability of the analysis. The tool presented here complements convergence diagnostics already available in other software packages primarily designed for other applications of MCMC. Importantly, the common practice of using trace-plots of a single parameter or summary statistic, such as the likelihood score of sampled trees, can be misleading for assessing the success of a phylogenetic MCMC simulation. Availability: The program is available as source under the GNU General Public License and as a web application at http://ceb.scs.fsu.edu/awty Contact: jwilgenb@scs.fsu.edu

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Metadata

Authors
Nylander, J. A. A., Wilgenbusch, J. C., Warren, D. L., & Swofford, D. L.
Venue
Bioinformatics
Published
2007-08-30
Volume
24
Issue
4
Pages
581-583
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2128841626
Cited by
1,747
References
10
FWCI
97.60
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: AWTY (are we there yet?): a system for graphical exploration of MCMC convergence in Bayesian phylogenetics. https://app.cochat.ai/papers/10.1093/bioinformatics/btm388
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Nylander, J. A. A., Wilgenbusch, J. C., Warren, D. L., & Swofford, D. L. (2008). AWTY (are we there yet?): a system for graphical exploration of MCMC convergence in Bayesian phylogenetics. Bioinformatics. https://doi.org/10.1093/bioinformatics/btm388

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