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The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Ontologizer 2.0—a multifunctional tool for GO term enrichment analysis and data exploration

Bauer, Sebastian, Grossmann, Steffen, Vingron, Martin, Robinson, Peter N.·2008·Bioinformatics

Abstract

Summary: The Ontologizer is a Java application that can be used to perform statistical analysis for overrepresentation of Gene Ontology (GO) terms in sets of genes or proteins derived from an experiment. The Ontologizer implements the standard approach to statistical analysis based on the one-sided Fisher's exact test, the novel parent–child method, as well as topology-based algorithms. A number of multiple-testing correction procedures are provided. The Ontologizer allows users to visualize data as a graph including all significantly overrepresented GO terms and to explore the data by linking GO terms to all genes/proteins annotated to the term and by linking individual terms to child terms. Availability: The Ontologizer application is available under the terms of the GNU GPL. It can be started as a WebStart application from the project homepage, where source code is also provided: http://compbio.charite.de/ontologizer Requirements: Ontologizer requires a Java SE 5.0 compliant Java runtime engine and GraphViz for the optional graph visualization tool. Contact: sebastian.bauer@charite.de; peter.robinson@charite.de

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Research works printed but not linked: 7

  1. Alexa, 2006, Improved scoring of functional groups from gene expression data by decorrelating GO graph structure, Bioinformatics, 22, 1600, 10.1093/bioinformatics/btl140 · DOI · Paper page
  2. Falcon, 2007, Using GOstats to test gene lists for GO term association, Bioinformatics, 23, 257, 10.1093/bioinformatics/btl567 · DOI · Paper page
  3. Gansner, 1999, An open graph visualization system and its applications to software engineering, Software Pract. Exper, 30, 1203, 10.1002/1097-024X(200009)30:11<1203::AID-SPE338>3.0.CO;2-N · DOI · Paper page
  4. Grossmann, 2007, Improved detection of overrepresentation of Gene-Ontology annotations with parent-child analysis, Bioinformatics, 23, 3024, 10.1093/bioinformatics/btm440 · DOI · Paper page
  5. Khatri, 2005, Ontological analysis of gene expression data: current tools, limitations, and open problems, Bioinformatics, 21, 3587, 10.1093/bioinformatics/bti565 · DOI · Paper page
  6. Liu, 2003, NetAffx: affymetrix probesets and annotations, Nucleic Acids Res, 31, 82, 10.1093/nar/gkg121 · DOI · Paper page
  7. Robinson, 2004, Ontologizing gene-expression microarray data: characterizing clusters with Gene Ontology, Bioinformatics, 20, 979, 10.1093/bioinformatics/bth040 · DOI

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Metadata

Authors
Bauer, S., Grossmann, S., Vingron, M., & Robinson, P. N.
Venue
Bioinformatics
Published
2008-05-29
Volume
24
Issue
14
Pages
1650-1651
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2116211027
Cited by
495
References
1
FWCI
10.30
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Ontologizer 2.0—a multifunctional tool for GO term enrichment analysis and data exploration. https://app.cochat.ai/papers/10.1093/bioinformatics/btn250
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Bauer, S., Grossmann, S., Vingron, M., & Robinson, P. N. (2008). Ontologizer 2.0—a multifunctional tool for GO term enrichment analysis and data exploration. Bioinformatics. https://doi.org/10.1093/bioinformatics/btn250

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