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DIANA-mirPath: Integrating human and mouse microRNAs in pathways
Open accessAbstract
Summary: DIANA-mirPath is a web-based computational tool developed to identify molecular pathways potentially altered by the expression of single or multiple microRNAs. The software performs an enrichment analysis of multiple microRNA target genes comparing each set of microRNA targets to all known KEGG pathways. The combinatorial effect of co-expressed microRNAs in the modulation of a given pathway is taken into account by the simultaneous analysis of multiple microRNAs. The graphical output of the program provides an overview of the parts of the pathway modulated by microRNAs, facilitating the interpretation and presentation of the analysis results. Availability: The software is available at http://microrna.gr/mirpath and is free for all users with no login or download requirement. Contact: papadopoulos@fleming.gr or hatzigeorgiou@fleming.gr
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Combinatorial microRNA target predictions
Krek, A., Grün, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., MacMenamin, P., da Piedade, I., Gunsalus, K. C., Stoffel, M., et al. (2005) · Nature Genetics · doi:10.1038/ng1536 · Cited by 4,603
Widespread changes in protein synthesis induced by microRNAs
Selbach, M., Schwanhäusser, B., Thierfelder, N., Fang, Z., Khanin, R., & Rajewsky, N. (2008) · Nature · doi:10.1038/nature07228 · Cited by 3,429
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Bourdon, J. A., Saber, A. T., Halappanavar, S., Jackson, P. A., Wu, D., Hougaard, K. S., Jacobsen, N. R., Williams, A., Vogel, U., Wallin, H., et al. (2012) · Environmental and Molecular Mutagenesis · doi:10.1002/em.21706 · Cited by 51
Cardiovascular Risk and Resilience Among Black Adults: Rationale and Design of the MECA Study
Islam, S. J., Kim, J. H., Topel, M., Liu, C., Ko, Y., Mujahid, M. S., Sims, M., Mubasher, M., Ejaz, K., Morgan‐Billingslea, J., et al. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.015247 · Cited by 23
Metadata
- Authors
- Papadopoulos, G. L., Alexiou, P., Maragkakis, M., Reczko, M., & Hatzigeorgiou, A. G.
- Venue
- Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-05-12
- Volume
- 25
- Issue
- 15
- Pages
- 1991-1993
- ISSN
- 1367-4803 (ISSN-L)
- 1367-4811
- OpenAlex
- W2113445340
- Cited by
- 274
- References
- 2
- FWCI
- 9.32
- Type
- journal article
- Language
- en
- Open access
- bronze
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