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PGAP: pan-genomes analysis pipeline

Open access
Zhao, Yongbing, Wu, Jiayan, Yang, Junhui, Sun, Shixiang, Xiao, Jingfa, Yu, Jun·2012·Bioinformatics

Abstract

Summary: With the rapid development of DNA sequencing technology, increasing bacteria genome data enable the biologists to dig the evolutionary and genetic information of prokaryotic species from pan-genome sight. Therefore, the high-efficiency pipelines for pan-genome analysis are mostly needed. We have developed a new pan-genome analysis pipeline (PGAP), which can perform five analytic functions with only one command, including cluster analysis of functional genes, pan-genome profile analysis, genetic variation analysis of functional genes, species evolution analysis and function enrichment analysis of gene clusters. PGAP's performance has been evaluated on 11 Streptococcus pyogenes strains. Availability:PGAP is developed with Perl script on the Linux Platform and the package is freely available from http://pgap.sf.net. Contact: junyu@big.ac.cn; xiaojingfa@big.ac.cn Supplementary information: Supplementary data are available at Bioinformatics online.

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Metadata

Authors
Zhao, Y., Wu, J., Yang, J., Sun, S., Xiao, J., & Yu, J.
Venue
Bioinformatics
Published
2011-11-29
Volume
28
Issue
3
Pages
416-418
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2117207428
Cited by
517
References
14
FWCI
4.35
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: PGAP: pan-genomes analysis pipeline. https://app.cochat.ai/papers/10.1093/bioinformatics/btr655
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Zhao, Y., Wu, J., Yang, J., Sun, S., Xiao, J., & Yu, J. (2012). PGAP: pan-genomes analysis pipeline. Bioinformatics. https://doi.org/10.1093/bioinformatics/btr655

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