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CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data

Open access
Bindea, Gabriela, Galon, Jérôme, Mlecnik, Bernhard·2013·Bioinformatics

Abstract

Summary: The CluePedia Cytoscape plugin is a search tool for new markers potentially associated to pathways. CluePedia calculates linear and non-linear statistical dependencies from experimental data. Genes, proteins and miRNAs can be connected based on in silico and/or experimental information and integrated into a ClueGO network of terms/pathways. Interrelations within each pathway can be investigated, and new potential associations may be revealed through gene/protein/miRNA enrichments. A pathway-like visualization can be created using the Cerebral plugin layout. Combining all these features is essential for data interpretation and the generation of new hypotheses. The CluePedia Cytoscape plugin is user-friendly and has an expressive and intuitive visualization. Availability: http://www.ici.upmc.fr/cluepedia/ and via the Cytoscape plugin manager. The user manual is available at the CluePedia website. Contact: bernhard.mlecnik@crc.jussieu.fr or jerome.galon@crc.jussieu.fr Supplementary information: Supplementary data are available at Bioinformatics online.

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Metadata

Authors
Bindea, G., Galon, J., & Mlecnik, B.
Venue
Bioinformatics
Published
2013-01-16
Volume
29
Issue
5
Pages
661-663
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2152026276
Cited by
1,061
References
5
FWCI
15.20
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data. https://app.cochat.ai/papers/10.1093/bioinformatics/btt019
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Bindea, G., Galon, J., & Mlecnik, B. (2013). CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data. Bioinformatics. https://doi.org/10.1093/bioinformatics/btt019

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