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MDSCs in Liver Cancer: a critical tumor-promoting player and a potential therapeutic target.

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Metformin and Docosahexaenoic Acid Hybrid Micelles for Premetastatic Niche Modulation and Tumor Metastasis Suppression

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STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pathway

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The tumour microenvironment in pancreatic cancer — new clinical challenges, but more opportunities

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Myeloid Cell Mediated Immune Suppression in Pancreatic Cancer

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Hepatic lipids promote liver metastasis

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Targeting TNF-α–producing macrophages activates antitumor immunity in pancreatic cancer via IL-33 signaling

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The interactive role of inflammatory mediators and metabolic reprogramming in pancreatic cancer

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Decoding the interplay between genetic and non-genetic drivers of metastasis

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The Tumor Microenvironment of Colorectal Cancer Metastases: Opportunities in Cancer Immunotherapy

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Cancer immunotherapy via synergistic coactivation of myeloid receptors CD40 and Dectin-1

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Overcoming immunotherapeutic resistance by targeting the cancer inflammation cycle

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TIMP1 expression underlies sex disparity in liver metastasis and survival in pancreatic cancer

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Mechanisms Governing Immunotherapy Resistance in Pancreatic Ductal Adenocarcinoma

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Organ Tropism in Solid Tumor Metastasis: An Updated Review

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Immune cell shuttle for precise delivery of nanotherapeutics for heart disease and cancer

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Serum amyloid A promotes glycolysis of neutrophils during PD-1 blockade resistance in hepatocellular carcinoma

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Cancer-induced systemic pre-conditioning of distant organs: building a niche for metastatic cells

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Gastric cancer-derived LBP promotes liver metastasis by driving intrahepatic fibrotic pre-metastatic niche formation

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Cruel to Be Kind: Epithelial, Microbial, and Immune Cell Interactions in Gastrointestinal Cancers

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TGF‐β signaling in liver metastasis

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Mechanisms of colorectal liver metastasis development

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Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice

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Cell cycle-related kinase reprograms the liver immune microenvironment to promote cancer metastasis

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Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic Cancer

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Hepatocyte-Driven Regulation of Liver Metastasis

Lee, J. (2019) · ScholarlyCommons (University of Pennsylvania)

Abstract 1102: IL-6/STAT3 activation in hepatocytes drives pro-metastatic niche formation in the liver

Lee, J. W., Thomas, S. K., Komar, C. A., Gladney, W. L., Hua, X., Xin, D., Shaked, A. A., Borad, M. J., Ramanathan, R. K., Ji, A., et al. (2018) · Cancer Research · doi:10.1158/1538-7445.am2018-1102

Abstract 2682: IL-6/STAT3 activation in hepatocytes drives the formation of a pro-metastatic niche in the liver during pancreatic tumorigenesis

Lee, J. W., Porrett, P. M., Komar, C. A., Gladney, W. L., & Beatty, G. L. (2017) · Cancer Research · doi:10.1158/1538-7445.am2017-2682

IL-6 drives niche formation in pancreatic cancer liver metastasis

Thomas, H. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0138-6 · Cited by 14 · see citing works

Abstract B014: TLR signaling coordinates SAA-dependent liver metastasis in pancreatic cancer

Lee, J., Stone, M. L., Choi, H., & Beatty, G. L. (2022) · Cancer Research · doi:10.1158/1538-7445.panca22-b014