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GSCALite: a web server for gene set cancer analysis

Open access
Liu, Chun-Jie, Hu, Fei-Fei, Xia, Meng-Xuan, Han, Leng, Zhang, Qiong, Guo, An-Yuan·2018·Bioinformatics

Abstract

Summary: The availability of cancer genomic data makes it possible to analyze genes related to cancer. Cancer is usually the result of a set of genes and the signal of a single gene could be covered by background noise. Here, we present a web server named Gene Set Cancer Analysis (GSCALite) to analyze a set of genes in cancers with the following functional modules. (i) Differential expression in tumor versus normal, and the survival analysis; (ii) Genomic variations and their survival analysis; (iii) Gene expression associated cancer pathway activity; (iv) miRNA regulatory network for genes; (v) Drug sensitivity for genes; (vi) Normal tissue expression and eQTL for genes. GSCALite is a user-friendly web server for dynamic analysis and visualization of gene set in cancer and drug sensitivity correlation, which will be of broad utilities to cancer researchers. Availability and implementation: GSCALite is available on http://bioinfo.life.hust.edu.cn/web/GSCALite/. Supplementary information: Supplementary data are available at Bioinformatics online.

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Metadata

Authors
Liu, C.-J., Hu, F.-F., Xia, M.-X., Han, L., Zhang, Q., & Guo, A.-Y.
Venue
Bioinformatics
Published
2018-05-22
Volume
34
Issue
21
Pages
3771-3772
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2804658429
Cited by
1,149
References
4
FWCI
16.09
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: GSCALite: a web server for gene set cancer analysis. https://app.cochat.ai/papers/10.1093/bioinformatics/bty411
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Liu, C.-J., Hu, F.-F., Xia, M.-X., Han, L., Zhang, Q., & Guo, A.-Y. (2018). GSCALite: a web server for gene set cancer analysis. Bioinformatics. https://doi.org/10.1093/bioinformatics/bty411

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