The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Infarcts in the posterior circulation territory in migraine. The population-based MRI CAMERA study
Abstract
In a previous study, migraine cases from the general population were found to be at significantly increased risk of silent infarct-like lesions in the posterior circulation (PC) territory of the brain, notably in the cerebellum. In this study we describe the clinical and neuroimaging characteristics of migraine cases with and without aura and controls with PC lesions. In total, 39 PC infarct-like lesions represented the majority (65%) of all 60 identified brain infarct-like lesions in the study sample (n = 435 subjects with and without migraine). Most lesions (n = 33) were located in the cerebellum, often multiple, and were round or oval-shaped, with a mean size of 7 mm. The majority (88%) of infratentorial infarct-like lesions had a vascular border zone location in the cerebellum. Prevalence of these border zone lesions differed between controls (0.7%), cases with migraine without aura (2.2%) and cases with migraine with aura (7.5%). Besides higher age, cardiovascular risk factors were not more prevalent in cases with migraine with PC lesions. Presence of these lesions was not associated with supratentorial brain changes, such as white matter lesions. The combination of vascular distribution, deep border zone location, shape, size and imaging characteristics on MRI makes it likely that the lesions have an infarct origin. Previous investigators attributed cases of similar 'very small' cerebellar infarcts in non-migraine patients to a number of different infarct mechanisms. The relevance and likelihood of the aetiological options are placed in the context of known migraine pathophysiology. In addition, the specific involvement of the cerebellum in migraine is discussed. The results suggest that a combination of (possibly migraine attack-related) hypoperfusion and embolism is the likeliest mechanism for PC infarction in migraine, and not atherosclerosis or small-vessel disease.
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Sorge, F., Simone, R. D., Marano, E., Nolano, M., Orefice, G., & Carrieri, P. (1988) · Cephalalgia · doi:10.1046/j.1468-2982.1988.0801001.x · Cited by 3,465
Ophoff, R. A., Terwindt, G. M., Vergouwe, M. N., van Eijk, R., Oefner, P. J., Hoffman, S. M. G., Lamerdin, J. E., Mohrenweiser, H. W., Bulman, D. E., Ferrari, M., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81373-2 · Cited by 2,339
Self-citationMigraine as a Risk Factor for Subclinical Brain Lesions
Kruit, M. C. (2004) · JAMA · doi:10.1001/jama.291.4.427 · Cited by 988
Self-citationCaplan, L. R., & Hennerici, M. (1998) · Archives of Neurology · doi:10.1001/archneur.55.11.1475 · Cited by 869
Arterial territories of the human brain: Cerebral hemispheres
Tatu, L., Moulin, T., Bogousslavsky, J., & Duvernoy, H. (1998) · Neurology · doi:10.1212/wnl.50.6.1699 · Cited by 614
Bilateral Spreading Cerebral Hypoperfusion during Spontaneous Migraine Headache
Woods, R. P., Iacoboni, M., & Mazziotta, J. C. (1994) · New England Journal of Medicine · doi:10.1056/nejm199412223312505 · Cited by 607
The prevalence and characteristics of migraine in a population-based cohort: The GEM Study
Launer, L. J., Terwindt, G. M., & Ferrari, M. D. (1999) · Neurology · doi:10.1212/wnl.53.3.537 · Cited by 587
Self-citationDucros, A., Denier, C., Joutel, A., Cecillon, M., Lescoat, C., Vahedi, K., Darcel, F., Vicaut, E., Bousser, M.-G., & Tournier-Lasserve, E. (2001) · New England Journal of Medicine · doi:10.1056/nejm200107053450103 · Cited by 569
Timing and topography of cerebral blood flow, aura, and headache during migraine attacks
Olesen, J., Friberg, L., Olsen, T. S., Iversen, H. K., Lassen, N. A., Andersen, A. R., & Karle, A. (1990) · Annals of Neurology · doi:10.1002/ana.410280610 · Cited by 567
Arterial territories of human brain: Brainstem and cerebellum
Tatu, L., Moulin, T., Bogousslavsky, J., & Duvernoy, H. (1996) · Neurology · doi:10.1212/wnl.47.5.1125 · Cited by 465
Cited by
Meschia, J. F., Bushnell, C., Boden-Albala, B., Braun, L. T., Bravata, D. M., Chaturvedi, S., Creager, M. A., Eckel, R. H., Elkind, M. S. V., Fornage, M., et al. (2014) · Stroke · doi:10.1161/str.0000000000000046 · Cited by 2,650
De Cocker, L. J. L., van Veluw, S. J., Fowkes, M., Luijten, P. R., Mali, W. P. T. M., & Hendrikse, J. (2013) · Cerebrovascular Diseases · doi:10.1159/000353668 · Cited by 1,156
Prevalence and risk factors of cerebral microbleeds: The Rotterdam Scan Study
Vernooij, M. W., van der Lugt, A., Ikram, M. A., Wielopolski, P. A., Niessen, W. J., Hofman, A., Krestin, G. P., & Breteler, M. M. B. (2008) · Neurology · doi:10.1212/01.wnl.0000307750.41970.d9 · Cited by 793
Migraine pathophysiology: lessons from mouse models and human genetics
Ferrari, M. D., Klever, R. R., Terwindt, G. M., Ayata, C., & van den Maagdenberg, A. M. J. M. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(14)70220-0 · Cited by 387
Self-citationWhite Matter Microstructural Integrity and Cognitive Function in a General Elderly Population
Vernooij, M. W., Ikram, M. A., Vrooman, H. A., Wielopolski, P. A., Krestin, G. P., Hofman, A., Niessen, W. J., Van der Lugt, A., & Breteler, M. M. B. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.5 · Cited by 335
Metadata
- Authors
- Kruit, M. C., Launer, L. J., Ferrari, M. D., & van Buchem, M. A.
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-07-08
- Volume
- 128
- Issue
- 9
- Pages
- 2068-2077
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- OpenAlex
- W2095637210
- Cited by
- 366
- References
- 35
- FWCI
- 11.36
- Type
- journal article
- Language
- en
- Open access
- closed
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