Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology
Spangenberg, Elizabeth E., Lee, Rafael J., Najafi, Allison R., Rice, Rachel A., Elmore, Monica R. P., Blurton-Jones, Mathew, West, Brian L., Green, Kim N.·2016·Brain
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- Additional file 1 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathyMonica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
- Additional file 3 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathyMonica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
- Additional file 3 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 8 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 5 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 2 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 4 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 10 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 3 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 5 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathyMonica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
- Additional file 1 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 2 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 1 of Functional role of brain-engrafted macrophages against brain injuriesXi Feng, Elma S. Frias, Paladini, Maria S., David Chen, Zoe Boosalis, McKenna Becker, Sonali Gupta, Liu, Sharon, Gupta, Nalin, Rosi, Susanna · 2021 · Figshare
- Additional file 8 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 1 of Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH)Rebecca Heinz, Susan Brandenburg, Melina Nieminen-Kelhä, Irina Kremenetskaia, Philipp Boehm‐Sturm, Vajkoczy, Peter, Schneider, Ulf C. · 2021 · Figshare
- Additional file 5 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 6 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 5 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 4 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathyMonica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
- Additional file 17 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 1 of Low-dose PLX5622 treatment prevents neuroinflammatory and neurocognitive sequelae after sepsisNils Mein, Nikolai von Stackelberg, Jonathan Wickel, Geis, Christian, Chung, Ha-Yeun · 2023 · Figshare
- Additional file 5 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 7 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 3 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 16 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 9 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 18 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 1 of Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNSLindsay A. Hohsfield, Allison R. Najafi, Yasamine Ghorbanian, Neelakshi Soni, Edna E. Hingco, Kim, Sung Jin, Ayer Darling Jue, Swarup, Vivek, Mathew A. Inlay, Kim N. Green · 2020 · Figshare
- Additional file 4 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 1 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 1 of Targeting the NLRP3 inflammasome in cochlear macrophages protects against hearing loss in chronic suppurative otitis mediaViktoria Schiel, Ritwija Bhattacharya, Ankur Gupta, Kourosh Eftekharian, Anping Xia, Peter L. Santa Maria · 2024 · Figshare
- Additional file 12 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 2 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 1 of Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD miceArgyro Thalia Delizannis, Annelies Nonneman, Wangchen Tsering, An De Bondt, Ilse Van den Wyngaert, Bin Zhang, Emily S. Meymand, Modupe F. Olufemi, Pyry P. Koivula, Shaniya Maimaiti et al. · 2021 · Figshare
- Additional file 6 of Constitutively active microglial populations limit anorexia induced by the food contaminant deoxynivalenolStéphanie Gaigé, Rym Barbouche, Manon Barbot, Sarah Boularand, Michel Dallaporta, Anne Abysique, Jean‐Denis Troadec · 2022 · Figshare
- Additional file 6 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 7 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 6 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathyMonica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
- Additional file 10 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 2 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathyMonica Xiong, Chao Wang, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
- Additional file 2 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 9 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 14 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 3 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 10 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 6 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 9 of Repopulated microglia induce expression of Cxcl13 with differential changes in Tau phosphorylation but do not impact amyloid pathologyBerke Karaahmet, Le, Linh, Monique S. Mendes, Ania Katarzyna Majewska, M. Kerry O’Banion · 2022 · Figshare
- Additional file 4 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 7 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
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- Additional file 13 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 15 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 1 of Knock-in models related to Alzheimer’s disease: synaptic transmission, plaques and the role of microgliaDiana P. Benítez, Jiang, Shenyi, Jack I. Wood, Rui Wang, Chloe M. Hall, Carlijn Peerboom, Wong, Natalie, Katie M. Stringer, Karina S. Vitanova, Smith, Victoria C. et al. · 2021 · Figshare
- Additional file 4 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 8 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
- Additional file 6 of Herpes simplex virus 1 accelerates the progression of Alzheimer’s disease by modulating microglial phagocytosis and activating NLRP3 pathwayZhimeng Wang, Liu, Jing, Han, Jing, Zhang, Tianyi, Shangjin Li, Hou, Yanfei, Su, Huili, Fangping Han, Zhang, Conggang · 2024 · Figshare
- Additional file 11 of A Trem2R47H mouse model without cryptic splicing drives age- and disease-dependent tissue damage and synaptic loss in response to plaquesKristine M. Tran, Shimako Kawauchi, Enikö A. Kramár, Narges Rezaie, Heidi Yahan Liang, Jasmine Sakr, Ángela Gómez-Arboledas, Miguel A. Arreola, Celia Da Cunha, Jimmy Phan et al. · 2023 · Figshare
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