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Cited by 273

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Size Matters: Cerebral Volume Influences Sex Differences in Neuroanatomy

Open access
Leonard, C. M., Towler, S., Welcome, S., Halderman, L. K., Otto, R., Eckert, M. A., Chiarello, C.·2008·Cerebral Cortex

Abstract

Biological and behavioral differences between the sexes range from obvious to subtle or nonexistent. Neuroanatomical differences are particularly controversial, perhaps due to the implication that they might account for behavioral differences. In this sample of 200 men and women, large effect sizes (Cohen's d > 0.8) were found for sex differences in total cerebral gray and white matter, cerebellum, and gray matter proportion (women had a higher proportion of gray matter). The only one of these sex differences that survived adjustment for the effect of cerebral volume was gray matter proportion. Individual differences in cerebral volume accounted for 21% of the difference in gray matter proportion, while sex accounted for an additional 4%. The relative size of the corpus callosum was 5% larger in women, but this difference was completely explained by a negative relationship between relative callosal size and cerebral volume. In agreement with Jancke et al., individuals with higher cerebral volume tended to have smaller corpora callosa. There were few sex differences in the size of structures in Broca's and Wernicke's area. We conclude that individual differences in brain volume, in both men and women, account for apparent sex differences in relative size.

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Metadata

Authors
Leonard, C. M., Towler, S., Welcome, S., Halderman, L. K., Otto, R., Eckert, M. A., & Chiarello, C.
Venue
Cerebral Cortex
Published
2008-04-24
Volume
18
Issue
12
Pages
2920-2931
ISSN
  • 1047-3211 (ISSN-L)
  • 1460-2199
OpenAlex
W2133463714
Cited by
273
References
6
FWCI
16.43
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Size Matters: Cerebral Volume Influences Sex Differences in Neuroanatomy. https://app.cochat.ai/papers/10.1093/cercor/bhn052
The paper
Leonard, C. M., Towler, S., Welcome, S., Halderman, L. K., Otto, R., Eckert, M. A., & Chiarello, C. (2008). Size Matters: Cerebral Volume Influences Sex Differences in Neuroanatomy. Cerebral Cortex. https://doi.org/10.1093/cercor/bhn052

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