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Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (April 2020)

Open access
Bhimraj, Adarsh, Morgan, Rebecca L, Shumaker, Amy Hirsch, Lavergne, Valery, Baden, Lindsey, Cheng, Vincent Chi-Chung, Edwards, Kathryn M, Gandhi, Rajesh, Muller, William J, O’Horo, John C, Shoham, Shmuel, Murad, M Hassan, Mustafa, Reem A, Sultan, Shahnaz, Falck-Ytter, Yngve·2024·Clinical Infectious Diseases

Abstract

Background: There are many pharmacologic therapies that are being used or considered for treatment of coronavirus disease 2019 (COVID-19). There is a need for frequently updated practice guidelines on their use, based on critical evaluation of rapidly emerging literature. The objective was to develop evidence-based rapid guidelines intended to support patients, clinicians, and other healthcare professionals in their decisions about treatment and management of patients with COVID-19. Methods: The Infectious Diseases Society of America (IDSA) formed a multidisciplinary guideline panel of infectious disease clinicians, pharmacists, and methodologists with varied areas of expertise. Process followed a rapid recommendation checklist. The panel prioritized questions and outcomes. Then a systematic review of the peer-reviewed and gray literature was conducted. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to assess the certainty of evidence and make recommendations. Results: The IDSA guideline panel agreed on 7 treatment recommendations and provided narrative summaries of other treatments undergoing evaluations. Conclusions: The panel expressed the overarching goal that patients be recruited into ongoing trials, which would provide much-needed evidence on the efficacy and safety of various therapies for COVID-19, given that we could not make a determination whether the benefits outweigh harms for most treatments.

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Metadata

Authors
Bhimraj, A., Morgan, R. L., Shumaker, A. H., Lavergne, V., Baden, L., Cheng, V. C.-C., Edwards, K. M., Gandhi, R., Muller, W. J., O’Horo, J. C., Shoham, S., Murad, M. H., Mustafa, R. A., Sultan, S., & Falck-Ytter, Y.
Venue
Clinical Infectious Diseases
Published
2020-04-27
Volume
78
Issue
7
Pages
e83-e102
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W3019235900
Cited by
1,033
References
10
FWCI
28.19
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (April 2020). https://app.cochat.ai/papers/10.1093/cid/ciaa478
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Bhimraj, A., Morgan, R. L., Shumaker, A. H., Lavergne, V., Baden, L., Cheng, V. C.-C., Edwards, K. M., Gandhi, R., Muller, W. J., O’Horo, J. C., Shoham, S., Murad, M. H., Mustafa, R. A., Sultan, S., & Falck-Ytter, Y. (2024). Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (April 2020). Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa478

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.