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Cited by 255

The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.

The Global Challenge of Carbapenem-Resistant Enterobacteriaceae in Transplant Recipients and Patients With Hematologic Malignancies

Open access
Satlin, M. J., Jenkins, S. G., Walsh, T. J.·2014·Clinical Infectious Diseases

Abstract

Carbapenem-resistant Enterobacteriaceae (CRE) are emerging global pathogens. The spread of CRE to transplant recipients and patients with hematologic malignancies has ominous implications. These patients rely on timely, active antibacterial therapy to combat gram-negative infections; however, recommended empirical regimens are not active against CRE. Approximately 3%-10% of solid organ transplant (SOT) recipients in CRE-endemic areas develop CRE infection, and the infection site correlates with the transplanted organ. Mortality rates associated with CRE infections approach 40% in SOT recipients and 65% in patients with hematologic malignancies. Given that the current antimicrobial armamentarium to combat CRE is extremely limited, a multifaceted approach that includes antimicrobial stewardship and active surveillance is needed to prevent CRE infections in immunocompromised hosts. Improving outcomes of established infections will require the use of risk factor-based prediction tools and molecular assays to more rapidly administer CRE-active therapy and the development of new antimicrobial agents with activity against CRE.

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Metadata

Authors
Satlin, M. J., Jenkins, S. G., & Walsh, T. J.
Venue
Clinical Infectious Diseases
Published
2014-01-23
Volume
58
Issue
9
Pages
1274-1283
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2114237392
Cited by
255
References
60
FWCI
11.18
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Global Challenge of Carbapenem-Resistant Enterobacteriaceae in Transplant Recipients and Patients With Hematologic Malignancies. https://app.cochat.ai/papers/10.1093/cid/ciu052
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Satlin, M. J., Jenkins, S. G., & Walsh, T. J. (2014). The Global Challenge of Carbapenem-Resistant Enterobacteriaceae in Transplant Recipients and Patients With Hematologic Malignancies. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciu052

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.