The DOI matches its Crossref record; 145 of the 145 references it cites were found in a registry or an index.
The rapid spread of carbapenem-resistant Enterobacteriaceae
Open accessAbstract
Carbapenems, our one-time silver bullet for multidrug resistant bacterial infections, are now threatened by widespread dissemination of carbapenem-resistant Enterobacteriaceae (CRE). Successful expansion of Enterobacteriaceae clonal groups and frequent horizontal gene transfer of carbapenemase expressing plasmids are causing increasing carbapenem resistance. Recent advances in genetic and phenotypic detection facilitate global surveillance of CRE diversity and prevalence. In particular, whole genome sequencing enabled efficient tracking, annotation, and study of genetic elements colocalized with carbapenemase genes on chromosomes and on plasmids. Improved characterization helps detail the co-occurrence of other antibiotic resistance genes in CRE isolates and helps identify pan-drug resistance mechanisms. The novel β-lactamase inhibitor, avibactam, combined with ceftazidime or aztreonam, is a promising CRE treatment compared to current colistin or tigecycline regimens. To halt increasing CRE-associated morbidity and mortality, we must continue quality, cooperative monitoring and urgently investigate novel treatments.
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Cites
1 retracted
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RetractedPerformance standards for antimicrobial susceptibility testing
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Global Spread of Carbapenemase-producing Enterobacteriaceae
Nordmann, P., Naas, T., & Poirel, L. (2011) · Emerging Infectious Diseases · doi:10.3201/eid1710.110655 · Cited by 2,378
Three Decades of β-Lactamase Inhibitors
Drawz, S. M., & Bonomo, R. A. (2010) · Clinical Microbiology Reviews · doi:10.1128/cmr.00037-09 · Cited by 1,709
Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections
Surawicz, C. M., Brandt, L. J., Binion, D. G., Ananthakrishnan, A. N., Curry, S. R., Gilligan, P. H., McFarland, L. V., Mellow, M., & Zuckerbraun, B. S. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.4 · Cited by 1,645
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Plasmids and the spread of resistance
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Cited by
Sequencing-based methods and resources to study antimicrobial resistance
Boolchandani, M., D’Souza, A. W., & Dantas, G. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0108-4 · Cited by 522
Self-citationDistribution of antibiotic resistance genes in the environment
Zhuang, M., Achmon, Y., Cao, Y., Liang, X., Chen, L., Wang, H., Siame, B. A., & Leung, K. Y. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117402 · Cited by 422
Multiscale Evolutionary Dynamics of Host-Associated Microbiomes
Ferreiro, A., Crook, N., Gasparrini, A. J., & Dantas, G. (2018) · Cell · doi:10.1016/j.cell.2018.02.015 · Cited by 127
Self-citationTeixeira, P., Tacão, M., Pureza, L., Gonçalves, J., Silva, A., Cruz-Schneider, M. P., & Henriques, I. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.113913 · Cited by 67
Metadata
- Authors
- Potter, R. F., D’Souza, A. W., & Dantas, G.
- Venue
- Drug Resistance Updates
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 29
- Pages
- 30-46
- ISSN
- 1368-7646 (ISSN-L)
- OpenAlex
- W2522806486
- Cited by
- 403
- References
- 145
- FWCI
- 11.77
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
